Anabolic Resistance: Why It Is Harder To Add Muscle Mass As We Age and How To Fight It

Nelson Vergel

Founder, ExcelMale.com
We lose muscle mass and strength as we age. This is known as sarcopenia.

Muscle loss could begin in our 30s. Genetics and lifestyle play a major factor and there is a lot of inherited individual variability
There are several reasons why we become weaker: Our nervous system becomes more inefficient, our muscle quality decreases, our anabolic hormone secretion decreases, our bodies develop chronic inflammation and anabolic resistance.

How to prevent age-related muscle loss: eat more protein – at least 1.2g/kg BW up to 2g+/kg (counter-indication: careful if you have damaged kidneys), strength training with high intensities and volumes, active lifestyle outside the gym, supplement various nutrients like vitamin E, D, and omega-3s (if you are deficient).
There are also riskier solutions, but for those you have to see your doctor.
Anabolic Resistance: Why it is Harder to Add Muscle Mass as We Age and How to Fight It • Sci-Fit

The post Anabolic Resistance: Why It Is Harder To Add Muscle Mass As We Age and How To Fight It appeared first on Testosterone Wisdom.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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