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Nutrition and Supplements
ALA and thyroid hormone
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<blockquote data-quote="Kaus Klinski" data-source="post: 156111" data-attributes="member: 39200"><p>Hi guys,</p><p></p><p>I think this topic is worth it to open up a new thread.</p><p></p><p>I decided to add some ALA to my post workout shake (about 250 mgs) to enhance glucose uptake/insulin sensitivity a little. </p><p></p><p>But now I found information that ALA may interfere with thyroid medication (levothyroxine) and I'm on T4. More specifically, ALA may interfere with the conversion of T4 to T3, but this issue is only mentioned with T4 substitution, i.e. levothyroxine intake.</p><p></p><p>Do you guys think there is any concern with low dose ALA supplementation once a day (250 mgs post workout) when I time the intake of the levothyroxine appropriately (many hours prior)? ALA has a very short half life of approximately 30 minutes.</p><p></p><p>I don't really see how this could be of concern anyway, because if ALA would somehow interfere with the conversion of T4 to T3, would'nt everybody on ALA have that problem? Why would it only concern substituted levothyroxine and not the endogenously synthesized T4? I don't get it, but it's mentioned on a lot of medical websites that ALA may have that effect.</p><p></p><p>However, here is a link to a study I found:</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pubmed/1815532" target="_blank">Effect of alpha-lipoic acid on the peripheral conversion of thyroxine to triiodothyronine and on serum lipid-, protein- and glucose levels. - PubMed - NCBI</a></p><p></p><p>Any opinions?</p><p></p><p>regards</p><p>Kaus Klinski</p></blockquote><p></p>
[QUOTE="Kaus Klinski, post: 156111, member: 39200"] Hi guys, I think this topic is worth it to open up a new thread. I decided to add some ALA to my post workout shake (about 250 mgs) to enhance glucose uptake/insulin sensitivity a little. But now I found information that ALA may interfere with thyroid medication (levothyroxine) and I'm on T4. More specifically, ALA may interfere with the conversion of T4 to T3, but this issue is only mentioned with T4 substitution, i.e. levothyroxine intake. Do you guys think there is any concern with low dose ALA supplementation once a day (250 mgs post workout) when I time the intake of the levothyroxine appropriately (many hours prior)? ALA has a very short half life of approximately 30 minutes. I don't really see how this could be of concern anyway, because if ALA would somehow interfere with the conversion of T4 to T3, would'nt everybody on ALA have that problem? Why would it only concern substituted levothyroxine and not the endogenously synthesized T4? I don't get it, but it's mentioned on a lot of medical websites that ALA may have that effect. However, here is a link to a study I found: [URL="https://www.ncbi.nlm.nih.gov/pubmed/1815532"]Effect of alpha-lipoic acid on the peripheral conversion of thyroxine to triiodothyronine and on serum lipid-, protein- and glucose levels. - PubMed - NCBI[/URL] Any opinions? regards Kaus Klinski [/QUOTE]
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ALA and thyroid hormone
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