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Proviron has antagonist effects at the estrogen receptor itself, similar to Masteron. I don’t take it anymore because my DHT levels are high from test alone. An effective dosage is 25 mg daily. It’s definitely worth trying it out. It does work very well at blocking many of the effects of estrogen. When I’ve taken too much Proviron, ~50 mg per day, it felt like I crashed my estrogen with too much Anastrozole.