Advanced Prostate Cancer Treatments & Side Effects

madman

Super Moderator


Chapters

1:13 Dr. Heath's opening remarks
4:20 Prostate cancer statistics
7:49 Clinical states model
9:22 Risk stratification and staging workup
11:26 FDA approved agents
13:55 Androgen pathway
15:33 Androgen deprivation side effects
18:09 Overall survival benefit with intensification
20:16 Treatment selection factors
23:00 Clinical considerations
23:43 Disease burden and disease presentation
24:25 Clinical trial updates
25:30 Real-world treatment intensification patterns
26:10 Global data
26:44 Chemotherapy side effects
27:40 Chemotherapy fitness
29:03 Chemotherapy in castrate-resistant disease
29:38 Prostate cancer clinical trial updates
33:10 DNA damage repair pathways
33:40 PARP inhibitors
35:15 PARP inhibitor side effects
36:20 Genetic testing results
37:56 Microsatellite instability-high cancer
38:53 Immunotherapy in prostate cancer
39:28 Sipuleucel-T
41:30 Radium-223
42:26 Radium study and data
43:22 PSMA
49:45 Novel targets in clinical trials
50:16 Dr. Moyad and Dr. Heath Q&A
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

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