A Deep Dive into Focal Therapies for Prostate Cancer

madman

Super Moderator


In this episode, Dr. Geo Espinosa sits down with Dr. Arvin George, a renowned urologic surgeon from Johns Hopkins specializing in prostate cancer, to delve into the world of focal therapy. They discuss what focal therapy is, its side effects, and various energy types used in treating prostate cancer. Dr. George explains the advancements in imaging, the importance of patient empowerment, and compares different therapeutic modalities like HIFU, cryoablation, TULSA, and more. This comprehensive conversation aims to inform patients about their options, helping them make empowered decisions regarding their prostate health.




Chapters

00:00 A Deep Dive into Focal Therapies for Prostate Cancer: Expert Discussion with Dr. Arvin George
05:17 History and Evolution of Focal Therapy
07:49 Insurance Coverage and Reimbursement
13:57 Overview of Focal Ablative Treatments
18:58 Logistics and Patient Experience
20:11 Choosing the Right Energy for Treatment
28:04 Patient Preferences in Prostate Cancer Treatment
30:24 The Role of PSMA PET Scans in Prostate Cancer
32:36 Choosing the Right Focal Ablative Treatment
43:43 Side Effects of Focal Ablative Therapies
47:53 Managing Recurrence After Focal Ablation
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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