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There is nothing linear in this game. By that, I mean what works for one person in regard to estradiol comtrol may well be utterly ineffective for another patient on the very same protocol. A more pertinent question is what is your doctor trying to do?


I suggest the goal here is to jack your testosterone to the sky, so that you will certainly "feel great" initially, slap an AI into the mix to combat the almost certain spike in estradiol and hope for the best. A cookie-cutter protocol. Not all men need to have levels at 1,000, to say nothing of 1,400, in order to feel their best. A protocol has to be individualized...and estradiol control, remember that e2 is a necessary hormone for men, is one of the most individualized values in the entire mix.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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