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  1. S

    Sex Differences in Association of Physical Activity With All-Cause and Cardiovascular Mortality

    https://www.sciencedirect.com/science/article/pii/S0735109723083134 During 4,911,178 person-years of follow-up, there were 39,935 all-cause deaths including 11,670 cardiovascular deaths. Regular leisure-time physical activity compared with inactivity was associated with 24% (HR: 0.76; 95% CI...
  2. G

    Average Injection Beginner TRT Dose

    For men, it seems the best the place to start is around 100mg weekly spread into a couple doses, but what if the best place for a woman to start? My wife was on cream for a couple months but it didn't move her numbers much (dose unknown but way too expensive) and now on 20mg every 2 weeks. Does...
  3. Melissa

    Breakthrough bleeding since April

    I need advice. My case is not straightforward. I am not expecting black and white answers but I would greatly appreciate any educated thoughts and suggestions. I have been trying to figure this out since April 2021. Background: 8 plus years postmenopausal intact female. Started HRT in December...
  4. S

    Does anyone know any women on HRT through Defy Medical ?

    I know that this could probably go in the Women HRT subforum, but that barely gets any traffic so I hope that this is okay. Do any of you guys have wives or girlfriends that go through Defy for HRT? If so, what are there experiences with Defy? I'm just hoping that they'll have the same...
  5. J

    Benefits and Risks of Testosterone Therapy in Women

    From The Lancet Journal of Diabetes and Endocrinology: Our meta-analysis showed that, compared with placebo or a comparator (eg, oestrogen, with or without progestogen), testosterone significantly increased sexual function, including satisfactory sexual event frequency, sexual desire pleasure...
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    Benefits of Testosterone for Post-menopausal Women

    A recent meta-analysis looked at the benefits and risks of testosterone therapy for postmenopausal women and concluded it was a safe and effective way to increase libido. The summary is available online, here is the conclusion : Testosterone is effective for postmenopausal women with low sexual...
  7. S

    Optimal PROGESTERONE for women on HRT ?

    Hi. My mother started hrt recently (T injections 2x5mg/week. Estradiol patch 3.8mg (replace it every 7 days) and oral progesterone 100mg every day) She is 56 in menopause Her labs on this protocol are T>> 116ng/dl 2 days after injection e2>> 30 pg/ml...
  8. H

    (not for me?) Hombre's TRT Log: 34yo, low E2, norm SHBG and LH [Defy]

    Height: 6ft (Lifetime underweight, never on any psych meds) Motivation (libido mainly): tried cialis Nov 2017 after a year long break and it wasn't working the same, sudden weak erections during porn use Feb 2018 (after 6 years of minimal porn use, nofap with relapses for 6 years), 10%...
  9. A

    Female blood work

    The following labs are for a 37 year old female. The tests shown were taken in my follicular phase. I started T therapy 2 weeks ago but I cannot figure out why the high level of progesterone wasn't discussed. We discussed low T, possible low thyroid (I have paperwork to have blood drawn for that...
  10. Vince

    Why some women orgasm easier than others (#blessed)

    Apparently there is a clitoris sweet spot — aka a perfect distance between where the clitoris sits in conjunction to the opening of the urethra — that allows for maximum orgasm potential. “It is suggested that 2.5 cm from clitoris to urethral meatus is the demarcation in predicting whether or...
  11. A

    High testosterone but low other hormones in women

    So my lady got labs finally, from discounted labs she had high natural total testosterone 54, 2.7 free T, but relatively low progesterone at 0.2, and 105 estradiol. This was 5 days after her period. What's strange is despite the high T she has low libido for 26 years old, (never is horny sex...
  12. Nelson Vergel

    FDA approves first treatment for sexual desire disorder

    The U.S. Food and Drug Administration today approved Addyi (flibanserin) to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. Prior to Addyi’s approval, there were no FDA-approved treatments for sexual desire disorders in men or women. “Today’s approval...
  13. Nelson Vergel

    Scream Cream to Increase Sex Drive and Orgasms in Women

    More info here:http://www.empowerrxpharmacy.com/libido-enhancement.html
  14. Nelson Vergel

    Soda consumption increase risk of hip fractures in postmenopausal women

    Source: Am J Clin Nutr Soda consumption and risk of hip fractures in postmenopausal women in the Nurses' Health Study; Fung T, Arasaratnam M, Grodstein F, Katz J, Rosner B, Willett W, Feskanich D; American Journal of Clinical Nutrition (Aug 2014) BACKGROUND The frequency of soda...
  15. Nelson Vergel

    Testosterone Nasal Gel Improves Orgasms in Women

    Trimel Pharmaceuticals Announces Positive Phase II Results for Tefina™ May 28, 2014 Women treated with Tefina™ 0.6 mg reported a statistically significant increase in orgasms versus placebo TORONTO (May 28, 2014) – Trimel Pharmaceuticals Corporation (TSX: TRL) announced today top-line results...
  16. Nelson Vergel

    The FDA Wants More Information about Flibanserin, the female Viagra

    " drugmaker working to develop a pill to boost sexual desire in women says regulators are demanding more studies on the experimental drug. Sprout Pharmaceuticals said Tuesday that the Food and Drug Administration wants to see more data on how the company's drug, flibanserin, interacts with...
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