t therapy

* Finally, Bernie noted unresolved controversies in the field, including the optimal duration of fertility-preserving therapies, long-term outcomes of hybrid regimens combining testosterone with hCG, and best practices for sperm recovery after prolonged testosterone exposure. She emphasized the...

Hitting the nail on the head here! * The panel unpacks why “normal ranges” don’t fit every individual, highlighting genetic differences in androgen receptor sensitivity (CAG repeats) and the need to tailor treatment to symptoms and biology rather than numbers alone. 4:20-6:07 * so we have...

Listen closely here! 11:55-12:13 * you only need testosterone levels up for about 4-6 hrs in the day to produce an effect which works through the androgen receptor, the androgen receptor is present in every cell in the body so its not just a sex hormone it is a health hormone Another...

As usual dropping some gems here!

The first thing Abraham Morgentaler learned about testosterone is that it’s a brain hormone. It was in a lab at Harvard, while an undergraduate in the late 1970s, where he had this realization: A castrated male lizard put in a cage with a female would not perform its mating ritual and would be...

All those dime a dozen run of the mill T-clinics! High dosed T off the hop with an AI thrown in to boot LMFAO! * He explains that medications such as anastrozole, hCG, clomiphene, and enclomiphene—tools used thoughtfully in academic urology for specific indications—are now often bundled...

Figure 1. Comparative overview of therapeutic approaches for male hypogonadism and metabolic dysfunction. The figure summarizes the key advantages and disadvantages of three main management modalities: GLP-1 receptor agonists (GLP-1 RAs), lifestyle modification (diet and exercise), and...

https://www.natesto.com/ Save on NATESTO® With Eligible, commercially insured patients may pay as little as $25 per month*, per claim maximums apply. THE NATESTO® SAVINGS PROGRAM IS NOT HEALTH INSURANCE. *Manufacturer Terms: The Natesto Savings Program is not health insurance. Program...

https://onlinelibrary.wiley.com/doi/10.1002/tre.70016 Abstract Testosterone replacement therapy has evolved significantly in recent years, driven by high-quality clinical evidence and expanded treatment options. The 2023 TRAVERSE trial provided definitive cardiovascular safety data, leading...

[42:22] — When rising testosterone doesn’t fix symptoms [43:24] — Free testosterone vs. total testosterone In this episode, Dr. Jesse Mills, Director of the UCLA Men’s Clinic, joins Mike Haney to explain what’s driving that shift and what today’s data-driven approach to men’s health looks...

* Elevated haematocrit is common with TTh, typically occurring within 3–12 mo. Levels up to 54% appear safe, but higher values may increase CV risk [15]. * Treatment adjustments are required for haematocrit >54% (requiring withdrawal and phlebotomy in high-risk cases) Fig. 1 –...

https://www.urologytimes.com/view/jesse-mills-md-outlines-the-pitfalls-of-bundled-trt-treatments Mills describes TRT not merely as a prescription but as an ongoing therapeutic relationship aimed at comprehensive, long-term wellness. In this video, Jesse N. Mills, MD, director of the Men's...

Cases submitted by attendees in advance will be presented by the moderator and discussed by the panel. Following the cases, time was reserved for “Ask the Professor” session. The panel reviewed and discussed submitted cases, providing expert insights on: • Complex diagnostic scenarios •...

In this episode, Dr. Alex Tatem sits down with world-renowned men’s health expert Dr. Mohit Khera to break down the real science behind testosterone — why men’s levels keep dropping, how to correctly diagnose Low T, the role of free vs total testosterone, the safety of TRT, and what the TRAVERSE...

https://mediasite.osu.edu/Mediasite/Play/0b9e03c2e9c84b5d8d22039ac667f4c41d Roger Harty, MD Endocrinology, Diabetes & Metabolism Clinical Assistant Professor of Internal Medicine DELATESTRYL® Testosterone Enanthate Injection, USP 200 mg/mL Take Home Points

* Pearlman and Khera dive into the next phase of medicine, where lifestyle modification becomes the true front line of prevention—before prescriptions or procedures. Khera calls it “Medicine 3.0”: preventing low testosterone, diabetes, heart disease, and sexual dysfunction through proactive...

In this episode, Dr. Brandon and Dr. Morgentaler talk about the groundbreaking moments that defined Dr. Morgentaler’s career—from challenging long-held medical dogmas about testosterone and prostate cancer to reflecting on courage, science, and the evolving state of modern medicine. Chapters...

One of the big boys in the field! Dr. Anawalt! Pay attention to the Q&A (43:20-56:30) especially when it comes to testing free testosterone! 43:20-46:27 - How do we assess for free testosterone? * There's a direct antibody assay (IA) that measures free testosterone it is notoriously...

* TRT may be appropriate for men with persistent symptoms and repeatedly low morning testosterone levels. The clinic counsels on realistic goals: improved sexual function, energy, strength, and sleep quality, while monitoring for potential risks such as erythrocytosis, blood pressure or lipid...

Hot off the press! 25th Annual Fall Scientific Meeting of SMSNA! Grapevine, Texas! Great presentation! 1:29:40-1:43:30 Conclusions

Clomid is old news! hCG + FSH is where it's at for restoring/maintaining fertility on or off exogenous T! 500IU 3x/week will restore normal ITT. Protocol is compounded purified preparations of hCG/FSH (3000 IU hCG + 75 IU of FSH) injected subcutaneously 3X/week (M/W/F). Lipshultz reboot...

* Recovery of the HPG axis and normal spermatogenesis after cessation of exogenous testosterone use is variable and linked to multiple factors, including length of use, dosage, and formulation [5,12,13]. Recovery from short-term use, less than one year, is typically possible without the aid of...

Welcome to Fertility and Other F Words, where Drs. Amy and Larry tackle fertility, sexual health, and everything in between—no topic too taboo, no question off limits. Dr. Amy Pearlman is a urologist and sexual medicine specialist dedicated to helping men and women optimize their sexual...

* Treating physicians should aim to prescribe the minimal required dosing to improve serum T and hypogonadal symptoms. * Clinical experience supports raising tT into the upper third of the normal range for patients who do not respond symptomatically at lower levels.64 * A patient’s...

[42:00] Fertility, LH/FSH suppression, and pilot study data =========== Testosterone levels have dropped by nearly 50% over the past 40 years, creating ripple effects in metabolism, mood, fertility, and longevity. In this episode, you’ll learn why hormones are declining across both men and...

* Acne and other cutaneous reactions vary by delivery method and patient susceptibility, emphasizing the need for clinician awareness, patient counseling, and better adverse event reporting. https://academic.oup.com/jsm/article/22/Supplement_4/qdaf320.197/8375218 Testosterone Replacement...

* Use of hCG+TRT suppressed LH and FSH (p<0.05), whereas CC+TRT was associated with reduction in FSH only (p=0.02). However, at 6 months, CC monotherapy was associated with significant increases in LH and FSH (p<0.001). As expected, all three treatments were associated with substantial increases...

* “[The label change] does not give a clean slate to [health care professionals] who are giving testosterone treatment to people who do not have low testosterone,” Dhindsa said. “[Some clinics] are overtreating men, and then they [need] a phlebotomy to deal with the effects of excessive...