shutdown

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Infrequent dosing to avoid shutdown…

This might seem stupid, but here me out…. Long story short: I have treatment/lifestyle/therapy resistant depression, mental fatigue, anxiety. You name it, I’ve tried it. Believe me. Both medical and underground. Doctors are at a loss. But one day I decided to try testosterone and….. bam. Total...
- Darkmode
- Thread
- Jun 4, 2024
- #tgel anhedonia anxiety depression dosing timing gel dosage mental focus mental health microdosing microdosing testosterone shut down shutdown theory
- Replies: 26
- Forum: Testosterone Basics & Questions
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Could there be any way to eke some usefulness out of remaining cypionate without shutting down?

I know the answer is NO, but feel free to humor me. Has anyone tried this, or does anyone have a hypothesis of how it might be able to be done? I'm off trt and producing. I have an open vial with 8mlx200mg left. Could there be a sweetspot where I might get some benefit taking a certain amount...
- Deleted member 42882
- Thread
- Jan 6, 2023
- cypionate shutdown
- Replies: 8
- Forum: Testosterone Basics & Questions
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Enclomiphene in lieu of TRT: Realistic option or is it even available?

I have reviewed the various posts here regarding employing enclomiphene as a "soft" alternative to going full-blown TRT. I am exploring beginning TRT and in light of my "normal" total T of 415 and marginally low free T of 6.1, I just am really hesitant to force shutdown when my nuts are making...
- Lumalux
- Thread
- Jun 15, 2022
- alternative to trt enclomiphene shutdown
- Replies: 16
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
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Low e2, high shbg; would a low dose T still shut me down?

I'm around 700 natural T due to high shbg-60ish, and e2 is low 16-19. Would a low dose of T cyp keep me from shutting down my natural T? My thinking is that the extra T would push down shbg, then e2 might slowly increase to mid 20s without a shutdown. I have been experimenting with T and had a...
- Vvs1
- Thread
- Sep 10, 2019
- shbg shutdown
- Replies: 11
- Forum: Testosterone Basics & Questions

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038