receptors

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LOW SHBG CURE

Gentlemen, there is a cure for Low SHBG FINALLY. And, It is tangible unlike the "keto diet and fasting". There is a newly approved drug that could easily more than double our SHBG and for many of us would mean a new life and TRT working. The drug is called Rezdiffra (Resmetirom) manufactured by...
- kashman112
- Thread
- Jun 13, 2024
- estradiol receptors shbg trt
- Replies: 10
- Forum: Testosterone Basics & Questions
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Effect of genetics on male secondary sex characteristics vs Low T

Hi all, Wondering how much genetics plays a role in secondary sex characteristics vs total testosterone levels. I read a paper (attached) which shows that professional athletes have testosterone levels around 500-600ng/dl, which is around my levels but i have very poor secondary sex...
- Welshlad87
- Thread
- Jun 5, 2023
- genetics genetics vs. low t low testoserone receptors shbg trt
- Replies: 3
- Forum: Testosterone Basics & Questions
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Does nandrolone activate progesterone receptors?

I’ve heard and read that nandrolone acts on the progesterone receptor. I’m wondering if this activation replaces taking exogenous progesterone at all, even if nandrolone won’t increase progesterone in the serum.
- Gman86
- Thread
- Aug 29, 2021
- activate nandralone progesterone receptors
- Replies: 22
- Forum: Clinical Use of Anabolics and Hormones
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Will TRT effectiveness decrease over the years?

Hi guys sorry if this has been answered before, search didn't bring up anything meaningful. As I'm about to start TRT hopefully soon, and as I'm only 35 years old, what I'm a bit worried about is that TRT might help my symptoms now - but if there would be some sort of decreasing effectiveness...
- krm
- Thread
- Aug 25, 2018
- decreasing effectiveness numb receptors
- Replies: 11
- Forum: Testosterone Basics & Questions

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038