ptsd

  1. madman

    The Surprising Effects of Psychedelics on 'Normal' Adults: Psilocybin 1 mg vs 25 mg dose

    Discover how a single high dose of psychedelic medicine impacts the neurological framework of individuals without pre-existing clinical conditions. This video breaks down a recent clinical trial evaluating psilocybin effects on healthy adults to understand its acute and long-term impact on the...
  2. Nelson Vergel

    The Psychedelic Medicine Pipeline 2026

    The psychedelic drug development landscape has reached an inflection point in early 2026, with Compass Pathways achieving the first positive Phase 3 psilocybin trial results in June 2025, while Lykos Therapeutics' MDMA rejection has reshaped industry expectations for regulatory rigor. Six...
  3. Nelson Vergel

    Ibogaine: Promise and Practicalities for Transforming Addiction Treatment

    Ibogaine is rapidly garnering attention as a potentially revolutionary treatment for addiction and related mental health disorders—a beacon of hope in landscapes often characterized by despair and systemic inadequacy. In a recent Fluence webinar, leading experts Dr. Bruno Rasmussen (Brazilian...
  4. madman

    We Need to Be More Open to Psychedelic and Alternative Treatments

    * Psychedelics are not panaceas, but they offer mechanisms of action distinct from conventional treatments. Substances such as MDMA, psilocybin, ibogaine, ketamine, and 5-MeO-DMT are demonstrating the capacity to disrupt entrenched neurobiological patterns associated with trauma, addiction, and...
  5. madman

    The promise of psychedelics

    Psychedelics have helped me and many others that I know through real dark times of addiction and depression. My own breakthrough with psychedelics provided the breaking down of my belief systems and reawakened an overwhelmingly empowering sense of my own ability to change. I’m super excited...
  6. madman

    The role of neurosteroids in post-traumatic stress disorder and alcohol use disorder

    Abstract Rates of alcohol use disorder (AUD) are increasing in men and women and there are high rates of concurrent posttraumatic stress disorder (PTSD) and AUD. AUD and PTSD synergistically increase symptomatology and negatively affect treatment outcomes; however, there are very limited...
  7. Nelson Vergel

    PTSD and Dementia Risk: A Potential Target for Early Intervention

    In a study consisting of more than 180,000 male veterans aged 55 and older, those diagnosed with PTSD had nearly 2-fold the risk of developing dementia syndromes such as Alzheimer disease, frontotemporal dementia, Lewy Body dementia, vascular dementia, and senile dementia compared to those...
  8. J

    Mefloquine toxicity

    I am looking for anyone who has suffered from Mefloquine toxicity. This is an antimalarial drug that was handed out willy-nilly by several different nations' militaries. I'm also looking for anyone who has filed for US VA disability for Mefloquine toxicity. I did talk with one guy who was...
  9. Nelson Vergel

    Israel Approves Compassionate Use of MDMA-Assisted Psychotherapy for PTSD

    On February 3, 2019, the Israeli Ministry of Health announced the approval of compassionate use for MDMA-assisted psychotherapy for posttraumatic stress disorder (PTSD), which will allow 50 patients to receive the therapy within a treatment protocol. Patients with PTSD will be eligible to...
  10. Nelson Vergel

    Psychedelic drugs could treat depression, and other mental illnesses

    "It seems that psychedelics do more than simply alter perception. According to the latest research from my colleagues and me, they change the structures of neurons themselves. My research group has been studying the effects of psychedelics on neuronal structure and function, and we found that...
  11. R

    Traumatic Stress widely overlook in health evaluations

    We see many threads here of members dealing with what may be symptoms of stress rather than side effects of their medication. Stress that is symptomatic and on going is TSD, related to PTSD. Quality of life is diminished, interpersonal relations suffer. In our highly competitive fast paced...
  12. Nelson Vergel

    Microdosing of Psilocybin Mushrooms

    I am hearing more buzz around research using psilocybin to treat PTSD and other mental health issues. Has anyone tried microdosing? A friend with PTSD asked me and I just started reading about it. Here is a good guide: THE ESSENTIAL GUIDE TO MICRODOSING PSILOCYBIN MUSHROOMS This thread is...
  13. Nelson Vergel

    Are your PTSD symptoms really a hormone imbalance?

    There are hundreds of thousands of people diagnosed with Post Traumatic Stress Disorder (PTSD) that are being treated with psychiatric medication and are not getting any better. They are dealing with insomnia, depression, anxiety, fatigue, decreased sex drive and substance abuse. Many of these...
  14. Nelson Vergel

    From Club To Clinic: How MDMA Could Help Some Cope With Trauma

    MDMA, often known as Ecstasy or Molly, has for decades been used as a party drug — consumed in clubs, fuel for all-night raves. But lately, the substance is also being used in very different settings, for a very different purpose: to treat post-traumatic stress disorder. The Food and Drug...
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