pregnenolone low

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Why does 100mg oral pregnenolone spike my libido beyond belief?

Hey guys, I’ve been on TRT for 7 years. I am on 200mg of test cyp EW split in 2 shots (Monday and Thursday). No HCG, no AI. Last bloods were 8 weeks ago. TT was 1100, E2 sensitive 40. I forgot what my SHBG was but I was right in the middle. I feel good here. Recently, I’ve been experimenting...
- Medicwithachub
- Thread
- Oct 10, 2022
- pregnenolone dhea pregnenolone low pregnenolone progesterone questions on trt
- Replies: 52
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
Pregnenolone and Progesterone for Men: Pharmacokinetics and Studies

"Pregnenolone can be administered orally, subcutaneously, intravenously, intranasally, and topically/transdermally. Oral pregnenolone has high metabolism and low bioavailability.28 It is lipophilic and readily crosses the blood brain barrier. There is very limited data on the pharmacokinetics...
- Nelson Vergel
- Thread
- Jun 5, 2021
- pregnenolone pregnenolone low
- Replies: 110
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
HELP PLEASE. Why is my pregnenolone so low, test is low, but DHEA and Free test through the roof.

CAN SOMEONE HELP ME MAKE SENSE OUT OF THIS Why is my pregnenolone so low, test is low, but DHEA and Free test through the roof. I'm not doing any steroids or TRT I workout 5 days a week 45 200 pnds LAB TEST RESULTS : SHBG 35 TESTOSTERONE SERUM 435 FREE TESTOSTERONE 54.4 HIGH DHEA...
- Severiano Fernandez
- Thread
- Aug 28, 2017
- Replies: 12
- Forum: Blood Test Discussion

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038