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  1. K

    How long does it take for HCG to kick in, or am I being impatient?

    Hello. Newbie here, based in the UK. Excuse long post. I’ve been on TRT for a decade now, for secondary hypogonadism, with many ups and downs. That darn pituitary gland! I’ll cover my full story another day, in case it helps others, but only in the past two years have I had treatment that has...
  2. madman

    Single axillary incision endoscopic surgery and liposuction for gynecomastia

    Single axillary incision endoscopic surgery and liposuction for gynecomastia (2023) Mustafa Tukenmez, MD, Selman Emiroglu, MD, Erol Kozanoglu, MD, Bora Edim Akalin, MD, Baran Mollavelioglu, MD, Neslihan Cabioglu, MD, Mahmut Muslumanoglu, MD Abstract Gynecomastia is a common type of breast...
  3. C

    Dangers of Raloxifene / gyno

    Hi. I have been on TRT for some years now. Feeling great. My girl is days away from having our first child, looking forward to it. For those wondering, I was on 115 mg testosterone enanthate (split 2* week mondays am and thursdays pm) and 500iu hcg EOD from january to july. We first got...
  4. madman

    Management of Gynecomastia

    Contemporary Management of Gynecomastia (2022) Dennis J. Hurwitz, BS, MD, Armando A. Davila, BS, MD INTRODUCTION/HISTORY/DEFINITIONS/ BACKGROUND Gynecomastia is a common benign enlargement of the breast occurring in more than one-third of males.1 Although the deformity can be fleeting, for...
  5. madman

    Gynecomastia resection plus high-definition liposculpture

    Gynecomastia Treatment through Open Resection and Pectoral High-Definition Liposculpture (2021) Alfredo E. Hoyos, M.D. Mauricio E. Perez, M.D. Rodrigo Domínguez-Millán, M.D Background: Male chest definition surgery and patients complaining of breast tissue overgrowth have been increasing in...
  6. madman

    Drug-induced gynecomastia

    Summary Objective: To review the evidence concerning treatment-related gynecomastia in patients taking spironolactone, antiandrogens, 5 alpha-reductase inhibitors, lipid-lowering, and psychotropic drugs. Material and methods: A search of Medline and EMBASE was performed up to 30 June 2021. We...
  7. madman

    Invited Discussion on: Gynecomastia and Chest Masculinization

    With this article [1] the authors fill a gap in the scientific landscape regarding gynecomastias and their treatment. In medicine, it is always desirable to have a complete and rigorous classification of each pathology, which should possibly be correlated precisely with the most effective...
  8. madman

    Imaging in gynecomastia

    Abstract Background. Gynecomastia (GM) is the benign proliferation of glandular tissue of the male breast. It is a common condition, which may occur physiologically and shows three age peaks during a male’s lifespan: infancy, puberty, and senescence. An underlying pathology may be revealed in...
  9. madman

    Gynecomastia and Chest Masculinization

    Abstract Background Gynecomastia is a common finding in males. Clinical aspect varies widely in world populations showing peculiar hallmarks according to different body shapes reflecting personal expectations; therefore, a surgical plan must be tailored on an individual basis to all types of...
  10. madman

    Gynecomastia: Ultrasound-Confirmed Classification Pertainent to Surgical Correction

    Abstract Background Gynecomastia is the most common form of breast alteration in men, due to the proliferation of the gland ducts and stromal components, including fat. In addition to the most obvious indications (weight loss, pharmacotherapy, and drug suspension), surgical treatment is needed...
  11. madman

    Minimally invasive treatment of gynecomastia by ultrasound-guided vacuum-assisted excision

    Introduction: Gynecomastia (GM) is a benign proliferation of glandular breast tissue in men. Some cases need surgical intervention. Traditional open surgery by the semicircular inferior periareolar incision is the most common surgical approach. In order to obtain better esthetic results, some...
  12. keithc2485

    Breast pain started from HCG. Question?

    Hey guys so it's been about nine weeks since I've added HCG to my trt regiment. I take a hundred mg of testosterone step unit weekly and have added 800 IU of HCG a week. No AI has been added yet because my levels were normal as of my last panel of blood. I don't next week for new blood work...
  13. Nelson Vergel

    Gynecomastia: Causes, Types, and Treatments.

    What is Gynecomastia and How to Diagnose it Gynecomastia is a benign enlargement of the male breast resulting from a growth of the glandular tissue of the breast, known as male breast tissue. It is defined clinically by the presence of a rubbery or firm mass extending concentrically from the...
  14. G

    Gynecomastia and T dosage

    Even though I inject just 25mg EOD, I have a gyno (moderate) and I had been leaner before TRT. Does it mean that I still need to inject less? Does gyno=excess T dosage? p.s. sensitive E2 test is not available here
  15. M

    Worried about Nebido and gyno

    Hello, new member and new to trt here. I've had basically no T production of my own after a brain surgery a few months ago, so my doc started me on my first shot 10 days ago, and while some things are slightly better already such as sleeping at night and some signs of a libido, im...
  16. V

    Chest fat or Gynecomastia? Can Test correct it?

    Hello again, sorry for posting so much but I have a lot concerning me atm. To preface, ever since I was a teenager and puberty started to take its toll on me, I have had extra tissue on my chest that has caused me much embarrassment and discomfort in my social life (I hate beaches/pools) and in...
  17. Nelson Vergel

    Gynecomastia: A Multicenter Study

    Highest prevalence of gynecomastia was observed between 21 and 30 years (n = 74; 31.2%). The most common presenting complaints were aesthetic concerns (62.8%) and breast pain (51.2%). 25.3% of the subjects had a history of pubertal gynecomastia. 56.5% had bilateral gynecomastia. 39.9% were...
  18. Nelson Vergel

    Statin Medications and the Risk of Gynecomastia

    Abstract Objective Case reports have suggested an increased risk of gynecomastia with HMG‐CoA reductase inhibitors (i.e. statins). A recent meta‐analysis also found that statins decrease circulating testosterone levels in men. We investigated whether statin use was associated with an increased...
  19. I

    Question about gynecomastia

    Hi. Let's assume that i was taking too much testosterone and it was converted into estriadol and i've developed some gyno. Now, will gynecomastia continue after i cut testosterone to normal range and estriadol came back to normal levels? Will breast tissue still grow after that or will it stay...
  20. C

    E2 at 51, to anastrozole or not to anastrozole

    I’ve been on TRT for over 1 year now and things are really going is looking much better from this side it just took a while. A million thanks for the people on this site and if you are beginning TRT give it time. I have been injecting every other day 0.25 ml testosterone cypionate...
  21. W

    Gynecomastia and Estradiol levels

    At what levels does high estradiol cause Gynecomastia?
  22. Nelson Vergel

    Estradiol in Men: Interview with Urology Professor Dr Ranjith Ramasamy

    Nelson Vergel, founder of and and author of Testosterone: A Man's Guide, interviews Dr Ranjith Ramasamy. Dr Ramasamy is the Director of Male Reproductive Medicine and Surgery as well as an Assistant professor in Department of Urology at the University of Miami...
  23. Nelson Vergel

    Proscar Can Increase Risk of Gynecomastia and Breast Cancer

    I have been saying for a while that estradiol is not the only factor involved in gynecomastia. Low DHT or a blocked DHT receptor can also be a risk factor. Also, remember that finasteride has also been linked to sexual dysfunction. If you have BPH, you are better off with an alpha inhibitor or...
  24. O

    Just done a blood test, need your opinion.

    Symptoms: Fatigue (sometimes severe), overweight, Gynecomastia, loss of memory and concentration, depression, acne, Age: 36 Male Height 5 11 , weight 222 , activity level:extremely low, very stressful life :( ..i take nexuim, addarel, fish oil, vitamins, calcium, magnesium, melatonin, OTC...
  25. F

    Exhaustion / Poor Sleep with High E2 and Gyno

    Current State: Hi, I am new here, a 30 year-old male with gyno (surgically removed) struggling with severe mental exhaustion / reduced brain cognition. No matter how much I sleep, I almost never wake up feeling rested. I wake up feeling like I haven't slept at all, or like I haven't slept in 2...
  26. Nelson Vergel

    Gynecomastia Surgery : Interview with Dr Joseph Cruise

    From Jay Campbell: I am very excited to present this interview I did with Dr Joseph Cruise. First a little backstory about gynecomastia. Gynecomastia, also known as ‘gyno’ is the over development of the male breast. Gynecomastia is a medical affliction estimated to affect more than 60% of men...
  27. H

    Lab results gyno symptoms

    After 10 weeks of 70mg testoterone cypionate 2x a week, 400iu hcg 2x a week and 0.25mg anastrozole 2x a week my lab results are: Total Testosterone 1331 ng/dl Free Testosterone 35.6 pg/ml Estradio sensitive 37.5 pg/ml So both T and estradiol a bit too high. Before starting this protocol i was...
  28. Nelson Vergel

    Not Higher Estradiol but Lower FSH , Sexual Function and Free T3 in Men with Gynecomastia

    They did not test IGF-1, one of the main factors involved in gynecomastia. Sexual function and hormone profile in young adult men with idiopathic gynecomastia: Comparison with healthy controls. Sir E, et al. Breast Dis. 2016. Abstract OBJECTIVES: To compare sexual function and hormone...
  29. Nelson Vergel

    Gynecomastia and Hormones

    Gynecomastia, commonly described as the enlargement of the male breast tissue, is clinically characterized by the presence of a mass extending concentrically from the nipple (e.g., bilateral or rarely unilateral). Gynecomastia is the most common breast alteration in males [1], occurring...
  30. Nelson Vergel

    DHT Gel Effectively Treats Gynecomastia in HIV + Men

    Successful Percutaneous Dihydrotestosterone Treatment of Gynecomastia Occurring during Highly Active Antiretroviral Therapy: Four Cases and a Review of the Literature Abstract Fourteen cases of gynecomastia occurring during highly active antiretroviral therapy (HAART) have been reported in...
  31. R

    The endocrinologist's guide to managing self-treating patients

    Male Central Hypogonadism Secondary to Exogenous Androgens Clin Endocrinol. 2015;82(5):624-632. In this paper a group of clinicians acknowledges that practitioners are encountering an increasing number of patients seeking help with recovery from self-administered anabolic steroids. [...
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