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  1. B

    New hypothesis: Free E2 rant, E2:SHBG ratios, why does no one bother

    So this relates to all forums, Reddit, various YouTube videos from doctors, pretty much every internet information source. As of the past few years all the rage and focus is on FT. So much so that certain tests are referred to with derogatory names. “Piss poor”. That’s how important FT is to...
  2. Nelson Vergel

    A novel spreadsheet method for calculating the free testosterone, free DHT, and free estradiol.

    Abstract In humans, testosterone (T), dihydrotestosterone (DHT), estradiol (E2), estrone (E1) and cortisol (C) bind to the serum proteins sex hormone-binding globulin (SHBG), albumin (Alb) and corticosteroid-binding globulin (CBG). Equilibrium dialysis is considered to be the "gold standard" for...
  3. S

    Spreadsheet for Calculating Free T & E2

    There's been a lot discussion recently in Excelmale on wanting to test for Free E2 and the relatively high cost of this test. There are online calculators which calculate an estimate of Free T based on Total T, SHBG and Albumin. However there doesn't appear to be an online calculator for...
  4. G

    Should Men on Testosterone Test Their Free Estradiol ?

    We really only care about free T levels, and don’t really even need the total level. So why is E2 different? Shouldn’t we only care about the free E2 level?
  5. C

    e2 vs free e2

    On another thread i posted, Vince Carter mentioned about also testing free e2. I've never heard about testing that so I'm really curious and trying to educate myself about it. Can one have normal levels of sensitive e2 yet have high free e2? If so, how would one address that problem?
  6. Nelson Vergel

    Should we monitor free estradiol ?

    Free Estradiol, Percent Reference Ranges (%) Age Range Adult Males 1.7 - 5.4 Adult Females 1.6 - 3.6 Free Estradiol, Serum Reference Ranges (pg/mL) Age Range Adult Males 0.2 - 1.5 Adult...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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