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  1. C

    A different dosing strategy with bremelanotide (PT-141) yields dramatically better results

    TL;DR: It may be possible to improve results with bremelanotide by taking multiple daily micro-doses. Like many, I have experimented with bremelanotide at the recommended doses, which range from a few hundred micrograms up to a couple milligrams in one subcutaneous injection. And also like...
  2. S

    Why so little info on Bremelanotide (PT-141-Vyleesi)?

    There is an astonishing lack of talk on here about a drug which attempts to address something that we talk about all the time and have zero tools to fix - libido. Now that we have multiple phase three studies to review on Pubmed and an FDA approved product perhaps we need to start gathering...
  3. G

    PT-141 officially FDA approved (for women)

    FDA approves new treatment for hypoactive sexual desire disorder in premenopausal women PT-141 AKA Bremelanotide AKA Vyleesi approved. This should open up a whole new focus on the melanocortin system and allow for crowdsourcing the best dosing/timing. It seems something good is happening in...
  4. Nelson Vergel

    Bremelanotide (Vyleesi) for Female Sexual Disorder

    Rekynda (bremelanotide), an investigational product, is thought to possess a novel mechanism of action, activating endogenous melanocortin pathways involved in sexual desire and response. The two Phase 3 studies for HSDD in pre-menopausal women consisted of double-blind placebo-controlled...
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