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Defy Medical TRT clinic doctor
  1. D

    Impact of TRT and Supraphysiological Testosterone Doses on Biological Aging

    I find it makes me look 5 years younger. Face looks more fresh, eyes sharper, and I like to do physical work for hours... Wondering if this will change in three years, or if I stop taking it, if I will look and feel older than if I never started it. @Nelson Vergel So the AI excerpt talks...
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    Brain health with trt, missed sleep

    ah ok. I use testosterone propionate and hcg. so is testosterone propionate actually anabolic steroid or not? yeah, bell shaped too little and too much... does anybody have the full study? can't access it over sci hub https://www.sciencedirect.com/science/article/abs/pii/S0306452224003063 how...
  3. D

    Anyone got a solid recipe for making scrotal testosterone cream (using testosterone base)?

    Hey, does anyone have a simple recipe for making scrotal testosterone cream? I’ve got testosterone base on hand and want to turn it into a cream, ideally something not too crazy, with easy-to-get ingredients and not too many steps. Maybe someone here has already done that and can recommend...
  4. D

    Impact of TRT and Supraphysiological Testosterone Doses on Biological Aging

    I've seen that some people measure their rate of aging using tools like genetic or epigenetic clocks (e.g., DNA methylation age). I'm wondering how different testosterone dosages, from standard TRT levels up to supraphysiological doses, might affect the speed of aging as measured by these...
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    Brain health with trt, missed sleep

    How did you notice worse cognitive function? Would you say this applies to everyone, and that people might be engaging in self-deception if they claim otherwise? I was diagnosed with ADHD and switched from stimulant medication to TRT. I’ve noticed that testosterone propionate feels like an...
  6. D

    Brain health with trt, missed sleep

    what is your reasoning behind this?
  7. D

    TRT and health tracking (e.g. sleep) with smart ring (oura)

    Are here people who use smart rings to track the effects of trt on sleep, hrv etc...? Or does anybody know if there groups, forums etc? Got oura ring and I am eager now to improve my sleep. Also courious what other things such a ring would be helpful for. I (m37, 25mg t prop, 150 IU hcg) tried...
  8. D

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    did you try it? how does it feel?
  9. D

    Brain health with trt, missed sleep

    I (m, 37) take 20mg testosterone proprionate IM and 150 IU Hcg IM. I noticed while travelling, that when I missed a night of sleep then the next day I didnt sleep much more. And I just can go on and still look the same and not much tired or something. I read about studies that showed that...
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    On TRT: How to check the state of cardiovascular system & how to find heart specialist

    do you know what dosage of k2? - do you know on what dosage of testosterone the doc is himself? - so you dont take any statin at all? - how would the statin worsen the metabolic health? (I might be able to switch out the 5mg rosuvastatine + 5mg ezetimibe with bempedoic acid 180mg + 5mg...
  11. D

    On TRT: How to check the state of cardiovascular system & how to find heart specialist

    Currently I (37m) am taking 20mg testosterone propionate and 150 IU hcg per day. doing that since a couple of months. I asked the doc if he can check my carotis intima and so on to see if there is soft plaque etc.... He said I need to go to cardiologist. Question is now how to find a good...
  12. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    ended up using the dht topical. Actually I liked the effect. gave me some buzz. had plenty of energy. actually a bit addictive. when using propionate before felt stressfull sometimes and emotionally a bit blocked. but not sure if it was because i was working all day when at home and using...
  13. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Ah yeah in your thread I also found viagra for cardiovascular health. Interesting. Can you recommend? This lowers blood pressure?
  14. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Natty I had around 550ng total t. So does 150 i.u. hcg not restore full testicular production with 550ng? What amount of fat would you suggest? Struggling to get Vitamin D to 50. Taking 10k i.u. daily since winter and before that 1k daily for two years or so. While supplementing 1k I was at...
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    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    today I compounded a scrotal cream myself — hydrogel with alcohol, around 100 mg/mL testosterone base. I applied about 1.5 mL this evening, so roughly 150 mg. But honestly, I have no clue how to interpret the effects. With propionate (20 mg/day), I had tons of energy all day — sometimes even...
  16. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Thanks for the in-depth explanation. Sounds like a very interesting book. I like the idea of a framework. I’ll definitely have a look. I'm curious: what are you doing for cardiovascular health? What changes did you implement after reading the book? On a different note: I not only ran out of...
  17. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Here are the full blood values in better image resolution. Link to images I asked ChatGPT to analyze the blood values based on the book "The Clot thickens". Actually not sure what sources ChatGPT used for this. :D Quick take Vascular protection looks good overall: LDL-C 46 mg/dL, TG 50 mg/dL...
  18. D

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    Who is using or has tried DHT enanthate? Can you share your dose and results, and whether you noticed any difference compared to unesterified (base) DHT? Also, how would you describe the effect of DHT for someone who’s never taken it?
  19. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Another quick update: my propionate ran out today, there might be a tiny amount left, but not even 20 mg. My supplier hasn’t delivered yet. What I have on hand is native testosterone (so I could make a topical) and testosterone cypionate. I’m debating whether to start the cypionate now or try...
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    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Yeah, I still need to read The Clot Thickens. I got the blood values from 01.08, but pregnenolone is missing—they didn’t run it. HDL and LDL aren’t moving. Hematocrit is now 47%; previously it was around 41% (no medication) to 44% (on enclomiphene). I’m not sure if ChatGPT calculated free...
  21. D

    Building a TRT protocol around hCG

    Any specific tests/metrics which you noticed are sensitive to changes?
  22. D

    Building a TRT protocol around hCG

    How would you go about doing cognitive testing? The only tool I really know is the free tool Brain Workshop (Brain Workshop - a Dual N-Back game) — I used it maybe a decade ago. It was quite fun back then, especially during the time when people believed that training on dual n-back could...
  23. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    ah yeah :D cortex normalizing insane amounts of prop :D so as I understood, estrogen has protective capabilities. With enclomiphene (and basically also without any SERMs) I had an LDL of 50, HDL of 36, total cholesterol 100. (5 mg ezetimibe + 5 mg rosuvastatin). Lp(a) is slightly elevated at...
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    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    That is very good to know! Shocking numbers? Any idea how much 150 IU hCG could actually put on top? Are there health risks involved with these peaks in my 20 mg + 150 IU daily combo? The Cortex Labs guy starts some clients at 20 mg prop (without hCG) and ramps up to 50–60 mg per day in some...
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    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Hey, do they replace it indefinitely? Couldn’t really find any clear info about that. Yeah, I’ll get one. Still figuring out if the RingConn 2 might be better—no subscription required, and someone mentioned the sleep tracking is more accurate (whatever that means exactly). Ah okay, so this...
  26. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Thx for the answers. just realized that the average lifespan of the batteries in these rings is 16 to 20 months—and the batteries are non-replaceable. Considering they cost $450, I’m a bit less inclined to buy now. Plus its a subscription model for the app. :D How helpful do you find the Oura...
  27. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Since a couple of days I got rid of all the Alcar and Alpha-GPC stuff from my system. Also no more Phenibut and Dexamphetamine since then. The Propionate seems like a better replacement. Energy levels feel way more consistent now. Current protocol: 20 mg Test Prop (sesame oil) IM daily 150 IU...
  28. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    How do you track it? Do you follow a specific structure?
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    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    I've been running now: First 1.5 weeks since 16th July: 15 mg Testosterone Propionate (subcutaneous) daily 150 IU HCG daily Experience: First day was great, then effects leveled off. Noticeable trough feeling in the morning. 25th July: Increased dose to 20 mg Testosterone Propionate...
  30. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Also, I noticed it takes me a while to get going in the morning — maybe 2 to 4 hours after pinning. I guess in the morning it's when T is at its lowest. I also read about the values from BillyJ03z Is there more data from other people available? I did read you can make a blend of prop and...
  31. D

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    yeah had to stop the DHEA and pregnenolone and now its much better. they just made me feel dumbed down, unmotivated etc.... is there a difference between ED and EOD/E3D? how much can a dose like 150 IU raise testosterone and E2 or is this very individual? Is there something like LH toxicity...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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