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  1. O

    REALLY Struggling With Weight Loss: What Labs to Run?

    Just as a sidebar, I had a check-up with my primary care doc yesterday for unrelated reasons - his thinking in looking at all of my labs, charts, etc from the past decade or so is that a GLP-1 is probably the move, especially given the fact that I haven't regained any weight from the last time I...
  2. O

    REALLY Struggling With Weight Loss: What Labs to Run?

    Thanks for the insights, y'all. I have taken @Guided_by_Voices' suggestion and booked an appointment with a well-regarded and highly-recommended holistic/functional medicine doctor in town who specializes in weight loss and hormone issues. I'd just like to make sure there isn't an underlying...
  3. O

    REALLY Struggling With Weight Loss: What Labs to Run?

    Hi y'all, for a bit more of my background (optional) I have a thread here about being on HCG Monotherapy for many, many years: Long-Term HCG Monotherapy Results and that'll go into some specific blood work. But here's the situation. I have kept 100lbs off for over a decade and cannot get the...
  4. O

    Long-Term HCG Monotherapy Results

    Howdy! Most recent bloods showed my Total T at 589ng/dL, which is a little bit low but it was at 11am and I did not sleep well at all the night before. E2 has also increased to 45pg/mL, which is higher than we'd like. We've put me back on a half mg of anastrozle per week and are going to...
  5. O

    Long-Term HCG Monotherapy Results

    Cheers, thanks! I've got blood work coming up in the next week or so and I'll try to remember to post my results. Anecdotally I still feel completely fine - I can still perform in the bedroom and I'm gaining muscle in the gym, no real issues there. One weird issue is my body fat distribution...
  6. O

    Kisspeptin-10 Instead of HCG?

    Huh, I am completely unfamiliar with this. Down the rabbit hole I go, I guess?
  7. O

    Is HCG still available?

    oh yeah, I factored a month of shipping time into my decision, but it's now been six weeks and they're still in Germany. Completely unjustifiable system we have here. Why did the new cheap generic increase in price 1000% overnight? Because fuck you, that's why!
  8. O

    Kisspeptin-10 Instead of HCG?

    Yes, secondary, thanks. And yeah, the only two things I can find about doing this are one guy who switched his HCG out for Kiss10 while already on test, but he posted on Reddit and hasn't responded to my threads or DMs, and one guy on T-Nation in 2022 who was taking 100mcg an hour and at that...
  9. O

    Is HCG still available?

    Yeah, I've got six vials coming, just didn't think German customs would hold on to 'em for 3 weeks on their way to the States.
  10. O

    Kisspeptin-10 Instead of HCG?

    Howdy y'all, As I've posted about in the past, I've been taking HCG Monotherapy for low T for about seven years now with good results - my last bloodwork had my total T at 707ng/dL with no change to my total weekly dosage since I started in 2017 (just tweaks to my dosing protocol)...
  11. O

    Is HCG still available?

    Bumping this out of frustration. The Fresenius Kabi generic has bumped up to $475 for a single 10mL vial, so I'm back to ReliableRX just because I can't afford that right now and I've found UGL HCG to be wildly unreliable in quality and potency. Is Reliable still the move? My order just finally...
  12. O

    Long-Term HCG Monotherapy Results

    Improving, but there’s a lot of other stuff going on there - as a formerly obese person my metabolism is quite slow, up until recently I worked a very sedentary job, and I take other medications that can impact body composition. I’ve actually got better insurance now and have already booked...
  13. O

    Long-Term HCG Monotherapy Results

    True! I meant it is higher than it historically has been for me and outside of the “normal” reference ranges for this lab, but you’re right, that context is important.
  14. O

    Long-Term HCG Monotherapy Results

    Six month update. I made no changes to my protocol other than dosing 300iu daily as described above for the reasons outlined in the studies above. I mentioned I felt great and the numbers bear that out: Total T 707 e2 39 (a little high but proportionately fine and I’m having no side effects...
  15. O

    Is HCG still available?

    Pregnyl has been out of stock/backordered at all of my local pharmacies for the last few months. I posted about this yesterday, but Rite Aid finally got me a generic HCG made by Fresenius Kabi, $199 for two 10mL vials, and my body seems to respond to it as well as as I've responded to Pregnyl...
  16. O

    HCG recommendations? Pregnyl vs Fresenius Kabi USA LLC generic

    Howdy! Sharing a post I made in another thread. I still need blood work done to verify, but anecdotally I feel as good on the FK generic as I did on pregnyl, which is better than I’ve felt on any other generic.
  17. O

    All HCG is NOT the same. Your balls care. Part 2

    Thanks, I’ll post in there too!
  18. O

    All HCG is NOT the same. Your balls care. Part 2

    I recently switched pharmacies due to cost - for whatever reason, my local Rite Aid is able to get Pregnyl at a significantly cheaper price than Costco, about $107 a vial after a GoodRX coupon (it's up to $267 at Costco as of the time of this writing!). However, nobody has been able to get...
  19. O

    Something for focus and clear brain fog if not a candidate for TRT

    "Brain fog" is a very nebulous set of symptoms - what is it, specifically, that you are noticing?
  20. O

    Long-Term HCG Monotherapy Results

    This is all without consulting all the notes I took at the time of diagnosis so details may be wrong or spotty, but my recollection is that I am primary. I believe that my LH and FSH were always "normal" but on the low end of normal - not in a way that suggested anything wrong with the...
  21. O

    What tests to do after 6 weeks of HCG monotherapy?

    I don't want to speak out of turn here, but in my non-professional opinion, you are doing too many things too quickly. You are 54 years old, on blood thinners, overweight, and don't exercise regularly. You got one blood test done, and two days later you ask for advice regarding it. @Systemlord ...
  22. O

    Long-Term HCG Monotherapy Results

    Alright, doctor is on board with my plan - I found a few more studies regarding the benefits of smaller, more regular doses, too, so that's also encouraging. We are going to re-test in a month. Also 2500iu twice a week was a typo on their end, thank goodness. If my current change to the dosing...
  23. O

    Long-Term HCG Monotherapy Results

    Anecdotal could-be-placebo results after four days of 300iu a day: holding surprisingly little water after a big holiday meal, libido through the roof.
  24. O

    All HCG is NOT the same. Your balls care. Part 2

    Yeah, I've bought the Sifasi and ZyHCG from them and it was "eh." - they nominally have Pregnyl, but I've never seen it actually in stock.
  25. O

    Long-Term HCG Monotherapy Results

    Totally, yeah. Also, I swore I wrote more in the above post. So, basically, I'm at 2,000iu right now, injected as 1,000iu twice a week. The doctor wants me to go up to 2,500iu twice a week (5000iu weekly). This is a non-starter for the simple fact that a 10000iu vial has just doubled in price...
  26. O

    Long-Term HCG Monotherapy Results

    Doctor says no tamoxifen, he doesn't use it. He wants me to drastically increase my HCG dose and drop anastrozole. I have proposed something different, because they cannot keep my dumb ass off of PubMed. This study found that daily, small doses of HCG not only prevent your leydig cells from...
  27. O

    Long-Term HCG Monotherapy Results

    Hi there! Thanks for hopping in. I’ll address these in order: re 1 and 2, if I understand you correctly, zinc and other things I may be taking may be inhibiting aromatization, explaining the low e2. This is possible but as the e2 has been low-ish about once a year since I started getting blood...
  28. O

    Long-Term HCG Monotherapy Results

    Eyyy, there’s a familiar name! And yeah, I mean, I certainly don’t feel as good as I did at 550 but I also don’t feel as bad as I did at, uh, 97. It’s very fuzzy, like I can’t articulate the specifics I just feel like I’m not feeling as good as I could be. But that could be unrelated to my...
  29. O

    Long-Term HCG Monotherapy Results

    I appreciate the perspective! I recently started taking a supplement containing boron, which can lower SHBG, so I may drop that as well. My apologies for not mentioning that in the original post. In the interest of completeness, the only other supplements I take are a stim-free preworkout, fish...
  30. O

    Long-Term HCG Monotherapy Results

    Alright, I've got an idea. I have read a few studies suggesting that tamoxifen citrate (Nolvadex) may have a synergistic effect in increasing testosterone in the case of long-term HCG monotherapy as it can block desensitization of the leydig cells (example: Tamoxifen suppresses...
  31. O

    Long-Term HCG Monotherapy Results

    Hi folks, Longtime lurker, first time poster. I see some familiar names here, though I tend to use different names on different forums. I am 34 years old. I've been on HCG Monotherapy for almost seven years now, starting in January of 2017. I was on clomid from 2014-2017, but we could never...
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