Busssaw "Polycythaemia, or erythrocytosis, means having a high concentration of red blood cells in your blood." NHS
True Polycythaemia and Erythrocytosis are used as interchangablly by many as in both red blood cell concentration is high but they are not the same . Polycytaemia Vera is...
I developed erythrocytosis and was intersted in the mechanism of this syndrom in relation to TRT.
The medical research in that area claim that testosterone inhibit hepcidin which control the iron metabolism.
Hepcidin invove in controling absorption of iron, as such too much iron pump in. This...
I thought Testosterone induces production of red blood cells via eryhropoitine production . But low levels of it with moderate testosteroe levels near 20nmole/L at peak make me to wonder about the mechanism of vaction. Through about 6 years of treatment hematocrit went up from about 40 to 54.7%.
Nelson Vergel , did you had a chance to read the article and find out what is the mechanism by which Testosterone cause the Erythrocytosis?
In my case I reached this stage though erythropoitien is low , JAK2 mutations none detected and T protocol T-enanthrate 0.25-0.3 ml/w eg 82-75 mg/W.
let me guess , I doubt that a clear cut conclusion will emerge soon as usually treatment is given as one "size fit all" with no proper adjustment for each case . Those elderly can be just drop dead with abrupt restoration of T level without first reaching the stage of clearing the buildup of...
drug - drug interaction and sleep
Nelson Vergel, I find your post as an opportunity to share my personal experiences with drug interactions that also shade light on sleep interruption among other issues. Most MD lack the education and training and time to help in that mater. I found that the...
Nelson, joining torrential with thanks for following and reporting.
In the past I used the SC method but due to large reactions developed initiating at the spots of injections I stopped using the SC method. (The study report a reaction defined as ecchymosis but I am not sure is the same)...
This is a Q of the Chicken and the egg. People with autoimmune diseases, as a fact are found on average to be with lower testosterone and other parameters. Low T is the cause or the result of is not a solved issue. other fact is that the gut is also protected /controlled by hormones...
some more aspects about the recommendation vote
"FDA Advisory Panel Urges Restrictions on Testosterone Use"
http://www.medscape.com/viewarticle/831897?src=wnl_edit_tpal
Limiting Testosterone
Hi guys. I think the issue is not well understood how FDA regulate drugs.
There are two main problems that worry the regulators on the issue of the enormous up use of testosterone and some data claiming bad outcome on patient.
Making claims by the pharma industry which...
Thank you MCBeastX . I join Nelson statement welcoming you and salute you for your fight! Nelson suggestion to help, make me feel sure that you will get proper medical attention when you will be back home.
I just want to point out that openness like yours, like Nelson's and others forming...
MCBeastX , Thanks a lot again for sharing . I am very sorry about all the trouble you went through.
Your story pretty much is the "same" story as of mine and others guys telling their story all around the globe. Though, details are different. Unfortunately, open mind MD to look at the big...
MCBeastX , thanks for sharing! of course you will be better at any treatment than without it. It would be nice if you can elaborate on how did you feel and managed while at high and at the time of low just before next injection. How were you monitored during that period by your doctor for the...
Thank you for the help and for being there for so many guys from different countries . I just learned that you also had a cancer issue among other issues . I am now 11 years in the business of CML and local prostate cancer. alive and kicking. I am a chemist in my education. I lived in the US...
Thanks Nelson, I have seen the comparison . The Q is whether the method is suitable for the purpose as you alwayes insiste on the sensetive method xxxxx. At this end of the globe the labs do not understand to which method you refer ( may be LC-MS/MS). This is a RIA method.As for your sugestion...
Dear Nelson,
My health provider finly agreed to provid me the information on the estradiol E2 test he uses :
"The ADVIA Centaur Enhanced Estradiol Assay".
The method is used for female and male . in the past he used also another kit called E2 low chiled.
can you coment on that test suitability...
That money is just small estimate. First they have to succeed in their phase 3 clinical trials. Get their marketing license and then think about marketing expenses. 10M $ is under estimate for an operation to convince MD start prescribing us the new drug.
General Information
Company
TesoRx Pharma LLC
Description
Oral pro-liposomal formulation of unmodified testosterone
Molecular Target
Mechanism of Action
Therapeutic Modality
Latest Stage of Development
Phase II
Standard Indication
Hypogonadism
Indication Details
Treat...
JUST TO REMEMBER, DRUGS ARE NO SWEETS THEY HAVE ALSO OTHER SIDE EFFECTS .
http://www.promescent.com/dapoxetine-and-priligy-peInter-Vaginal Latency Time
For men with an average baseline IELT of 0.9 minutes, the average IELT improved to 3.1 minutes for a 30mg dose and 3.6 minutes for a 60 mg...
dunemedic , sorry that I can't help, I am located at the other side of the globe. Recall that at the facebook forum Jasen Bruse was mentioned as a person that can help , look for the post of Joel Vail posted July 24 at 7:09pm · Tucson, AZ, United States
dunemedic- you have the right to be involved in your treatment but it the physition right to prescribe or not. So you know that you can vote with your feet. Go find a different MD you are comfortable with and find whether you realy need the extra medications. You do not need MD who just...
what do you mean? I try to understand what is the vehicle composition they are using in their final phase 3 . e.g Oil preservative etc (inactives) testosterone enanthate is the active) . AT http://clinicaltrials.gov/show/NCT01887418 phase 1 and 2 they desined the trail with two compositions of...
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