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Defy Medical TRT clinic doctor
  1. W

    TRT Peaks and troughs or steady levels. Which is correct?

    As @BadassBlues pointed out, the ebb and flow is what creates balance. For example, quite a few of us here have experimented with blends of medium and fast acting esters to create a spike in the morning with a trough at night instead of a constant state of CNS arousal 24 hours a day. I...
  2. W

    T Propionate protocol

    Funk can you explain how the testing works with this Janoshik? Are individuals sending him samples to test? Or is he doing it on behalf of suppliers?
  3. W

    New blood work after 12 weeks on 50mg/2x week

    Sounds like you are doing well with minimal side effects. One piece of advice - don't chase numbers that look ideal on paper. While ranges can certainly help guide you, we all respond a bit differently as you will see on this forum. Some guys feel great at 900 TT / 20 FT while others feel like...
  4. W

    New blood work after 12 weeks on 50mg/2x week

    Great numbers on paper, but how do you feel? Are you getting symptom relief for hypogonadism? Any side effects?
  5. W

    Impact of TRT and Supraphysiological Testosterone Doses on Biological Aging

    I have read quite a few anecdotes over the years about guys feeling like TRT makes them look aged. From personal experience, I think its the water bloating that does it, especially in the face with telltale circles under the eyes. On the classic cypionate dose of 100mg per week (E3.5 days)...
  6. W

    Dialed in on Testosterone Propionate, How to Switch to Cypionate

    I recall that you are the Natesto connoisseur ! It seems like a combination of the "bottoming out" plus the E2 tail from the earlier peak (E2 follows T - one of the first rules I learned here!)
  7. W

    My protocol managing hct and libido

    I had tried E3D before and now trying daily. To be honest, its not going well. I just feel like garbage on the stuff, even Pregnyl.
  8. W

    My protocol managing hct and libido

    Good to see update from you MJ. Some of your previous posts about protocol change still resonate with me because the only times I've gotten flashes of libido on TRT were from dose changes (or when stopping TRT). The one recent exception was libido from low dose no tester T, in this case...
  9. W

    7.5mgs daily labs

    You started the smart way. When/if the time comes, its easy to titrate up versus down.
  10. W

    Updated Labs - Help Please

    Good luck Craig. That T blend might be the oddest one I've seen yet!
  11. W

    Updated Labs - Help Please

    I would suggest getting new vial of testosterone or better yet a different brand. Either you are not delivering the T correctly as Funk mentioned or there is something wrong with the T
  12. W

    Updated Labs - Help Please

    TT 706 ng/dL with highish SHBG 44.8 nmol/L on 20mg TC daily seems way too low. Something off there...
  13. W

    New to TRT. Received first labs. Concerned and need help.

    Its a great discussion to have because Phil and Cat represent two different schools of thought. That's what makes this forum so invaluable versus the steroid culture chat groups. Agreed it would be better if posted in standalone thread. But damn I wish could have seen their discussion early...
  14. W

    New to TRT. Received first labs. Concerned and need help.

    He lost me when he started talking about titrating up from 120 mg :D which he acknowledges will already put most men at top of range or even well above it. Its like saying one martini makes you feel good so why not two?
  15. W

    New to TRT. Received first labs. Concerned and need help.

    While there may be other causes, these symptoms are very common for older men (the mid-50 doldrums!). It sucks but its the unfortunate reality of getting older. If you find the solution, let me know.
  16. W

    Pain after subq injections

    For subq, most use much thinner gauge needle of 30 or 31 with short length of 5/16. Injection in belly fat https://www.excelmale.com/threads/daily-subqers-5-stars-for-bd-ultra-fine-insulin-syringe-31g-3-10cc-5-16.24643/
  17. W

    Giving up on TRT after 5 years

    Respect for the rant and for being honest with yourself. I too have questioned many times whether TRT is worth it and have quit on several occasions only to return for some reason. I think a big part of it is general dissatisfaction with life after 50. For me, TRT has been neither the cure nor...
  18. W

    TRT Dose question

    Cialas/viagra targets ED - i.e., the mechanical aspect. Whereas lack of libido refers to no interest in sex - i.e., the mental piece. You can have one without the other.
  19. W

    TRT Dose question

    It is confusing because most of AAS articles appear to refer to TNE as oil base (sometimes just referred to as "Base) whereas Suspension refers to water. Either way there is no ester, but the two can be different in terms of absorption rate and PIP.
  20. W

    TRT Dose question

    Same exact experience here. At top of range, I have sub-zero libido if that is possible (at least pre-TRT I have occasional flashes). I have mid-high SHBG of 40-45 I continue to be jealous of guys who experience raging libido at supraphysiologic levels. If only...
  21. W

    TRT Dose question

    I am a daily low dose subq guy and have found that anything over 6mg TE daily will result in early AM awakenings which leaves me feeling shitty rest of the day. I am currently adding 2mg TNE to my daily base of 6mg TE to provide a morning spike. The fast acting TNE is out of the body by...
  22. W

    TRT Dose question

    Are you having trouble sleeping both peak and trough day? IM or subq?
  23. W

    TRT Dose question

    Good news that you are feeling better. Are you still experiencing crappiness day after injection? Are you going to stick with 1x per week shallow IM?
  24. W

    HCG induced aromatase down regulation?

    HCG causing drop in E2 - you and @FunkOdyssey need to switch places :cool: (see thread below). Joking aside, I've never seen anyone on this forum experience lower E2 from HCG. I am a low E2 guy about to add HCG (Pregnyl) to my low dose regiment. I will let you know if something similar occurs...
  25. W

    Building a TRT protocol around hCG

    So are you officially done with the HCG? Or will you adjust and try again?
  26. W

    Building a TRT protocol around hCG

    Appreciate the results @FunkOdyssey . That is quite a jump in E2. Why would the bolus from larger, presumably less frequent dose improve the disrupted neurosteroids verus daily?
  27. W

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Most definitely. I keep a TRT journal and have had quite a few entries about glorious days following TP increase. Then leveling out to point of emotional blunting. Its a tricky balance. One suggestion - don't track day-by-day. Too many variables at play.
  28. W

    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    So in theory that would bump you bump to TT 800? I see a new product in development! Speaking of fast acting T, a little goes a long way. When adding TNE (oil based) to my daily TE protocol, I have noticed that 2mg TNE seems to my sweet spot for a morning spike, subjectively speaking. I...
  29. W

    Building a TRT protocol around hCG

    So overall nothing positive. Bummer. Let us know your test results and if you try the 75 iu daily after your trip.
  30. W

    Building a TRT protocol around hCG

    Damn that is disappointing. I was inspired by this post to order some Pregnyl from Defy. Any comments on other areas such as sleep, mental cognition, energy levels, athletic performance?
  31. W

    First set of Follow Up Labs since Starting TRT. Looking for Feedback

    Congrats you've just prescribed 1.7x the levels of a healthy young male! That dose would put me at around 1200 TT In the end, its a helluva lot easier to titrate up then down. But who are we kidding with this debate - the elephant in the room is that clinics are always going to over-prescribe...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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