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"Dermatologic use is topical and ultralow: 0.1–2.5 μM, reapplied daily in lab studies. No human in-vivo wrinkle trials have yet published optimal gram-per-day figures" Interesting. I am currently searching for a quality MB topical, but I may just add some MB to my GHK topical cream.

Regardless, your best bet is to begin a protocol to boost your metabolism and a diet that works for you to achieve a calorie deficit. I respond well to Keto, but there are other options.

Do any of your other family members have the same physiology? You may just have a genetic predisposition to accumulate fat in your thighs and legs. I have this tendency as well. I can tell when I am gaining weight as my pants get tight in the thighs. The belly fat comes later as it progresses...

https://www.foxnews.com/health/cancer-could-detected-three-years-before-diagnosis-experimental-blood-test Researchers at Johns Hopkins University say they have uncovered an advanced method for detecting cancer. A new study, published in the journal Cancer Discovery and partly funded by the...

So, at 25mg a week you have 10 months of product. At 50mg per week you have 5 months of product. At 210.00, that's not a bad deal.

Interesting. 210.00 isn't a bad price if it works as stated. I'm curious as to the half life, would it be safe to assume it would be the same as TE? It's a 10ml vial at 100mg/ml so you have quite a few doses there. What is the recommended dosage? Here is the link to buy...

I much prefer PhloJel Ultra, but it has to be shipped from Canada and since it is technically a medical product it has to go through customs. If you order it, order a lot. The DMSO works just as well, but it doesn't have the same consistency. I just made a new batch with the DMSO.

I use this product. Works great and smells good...

Sun exposure will definitely increase the effect, but it will make you darker even without the sun. It can also cause moles. Use it sparingly. It makes me horny as Hell too.

I was about to say almost all of those same things. To question the need for fiber in your diet is pretty silly. It has more to do with digestion than nutrition. Fiber cleans out your intestines and colon and aids in other digestive functions. Those who are anti carnivore use the argument that...

“Genetically prone “ That’s a major factor. https://www.pfsfoundation.org/news/search-for-sources-of-major-pfs-symptoms-pinpoints-186-brain-genes/

Please post it.

https://www.ncbi.nlm.nih.gov/books/NBK557536/ Biochemistry, Lactate Dehydrogenase Aisha Farhana; Sarah L. Lappin. Author Information and Affiliations Last Update: May 1, 2023. Go to: Introduction Lactate dehydrogenase (LDH) is an important enzyme of the anaerobic metabolic pathway. It belongs...

Structures and mechanism of human mitochondrial pyruvate carrier Jiaming Liang, Junhui Shi, Ailong Song, Meihua Lu, Kairan Zhang, Meng Xu, Gaoxingyu Huang, Peilong Lu, Xudong Wu & Dan Ma Nature (2025)Cite this article 5230 Accesses 16 Altmetric Metricsdetails We are providing an...

https://www.prnewswire.com/news-releases/pelage-presents-late-breaking-data-at-aad-2024-meeting-demonstrating-pp405-activates-human-hair-follicle-stem-cells-ex-vivo-and-in-phase-1-clinical-study-302084610.html PP405 is a potent topical mitochondrial pyruvate carrier (MPC) inhibitor that acts on...

https://www.peptidesciences.com/catalogsearch/result/?q=hgh

The potential to add this to the already effective Minoxidil / Finasteride topical sounds like a possible winner. I use a blend of this with 15% Minoxidil and 1% Finasteride. I have had very good results.

This looks promising! https://www.universitycube.net/news/ucla-pp405-hair-restoration-breakthrough-therapy-03-26-2025--5d95ec49-5896-4d43-b0dc-04ac8e806687 UCLA Scientists Unveil PP405 Molecule, Promising Breakthrough in Hair Restoration Therapy 200 views Key Takeaways 3/26/2025 Aa Medicine A...

What he^ said, plus 500 IU's is a fairly big dose, get your labs done before and after about 6-8 weeks to see where your levels have shifted. Watch for symptoms of elevated E2. That will be a major change all at once with the HCG and changing your TRT protocol. I will tell you this, and I...

Yes, there is a chance it will reverse some of the atrophy. It may also help with your libido issues. I am also 68 and am an advocate for HCG for those on TRT. The loss of luteinizing hormone from the HPTA being shut down has other consequences than just testicular atrophy. There are LH...

Reliable is reliable ;) I have used them for years.

Ahhh... I have absolutely no experience with any oral forms.

Sorry buddy, I'm not understanding. Big fluctuations would be more in line with Propionate. Did I misunderstand you?

I assumed that, it does get old after a while. I go through cycles of multiple daily injections with peptides. It's nice to take a break from being a pincushion from time to time. With that said, I am about to start a 10 day Epithalon course next week. This along with daily peptides. I keep...

Very true. Cypionate is slow and predictable and keeps levels fairly consistent with regular dosing. Propionate peaks faster and isn't as predictable. Those changes will have an effect on many things, libido, mood, neurotransmitters etc... Propionate hits me at about the 5-hour mark and it...

I have to ask, if you are dialed in and things are good, what is your reasoning for wanting to change?

I believe it is in this thread, read back around the beginning. If not, PM me.

Please correct me if I am wrong, but to my knowledge athletes aren't tested for stanolone, but rather stanozolol. Testing for stanolone would be the equivelant of testing for testosterone. https://www.usada.org/spirit-of-sport/what-is-stanozolol/

Likely variable depending on dosage and frequency. Metformin is taken daily in most instances and doesn't clear the system. I'll do a search on that topic later when I have some time.

"I would argue that this demographic is more likely to have chronically elevated mTOR for various reasons and, for anti-aging purposes, is more likely to benefit from reduced mTOR." I believe you may have misread my thoughts on this as I agree with that. I am questioning the balance.

I don't think the biweekly protocol could, or should cause any problems with protein synthesis as there is sufficient time for the drug to clear and for mTOR1 to be reactivated. I am seeing protocols of weekly doses up to 10mg being prescribed by some clinics and that is what seems excessive to...