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Shbg inflates Estradiol labs?

Hi all, During my consultation with Dr Calkin from Defy, he mentioned SHBG artificially inflates Estradiol. I’ve never read this is any of the high SHGB posts I’ve seen on here. My sensitive Estradiol lab reading was 28.9 (8.0-35 pg/ml). Dr Calkin said in reality it’s probably around 15. He...
- BCD19800
- Thread
- Dec 17, 2018
- shbg and estradiol receptor
- Replies: 9
- Forum: Blood Test Discussion
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SubQ - Really that much better?

Hi all, I read some articles that references Dr Crisler regarding Subq injections. From what I read, seemes like Dr Crisler suggests SubQ is 20% more effective than IM as far as absorption and may lower estrogen conversion. Any personal experiences in relation to those benefits?
- BCD19800
- Thread
- Dec 17, 2018
- subq injections
- Replies: 1
- Forum: Testosterone Basics & Questions
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Which Research Publicatons to Bring?

Hi all, I’m in the process of scheduling a consultation with Defy but also wanted to visit a Urologist in-person for a consultation to discuss TRT and some post vasectomy pain. I have an upcoming appointment with Dr. Melograna from MidAtlantic Urology. Other members have posted about him on...
- BCD19800
- Thread
- Dec 8, 2018
- bioavailable testosterone shbg
- Replies: 0
- Forum: Testosterone Basics & Questions
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Starting protocol for high SHBG

Good afternoon, After doing more research and reviewing the responses to my other thread, I’ve decided to schedule an appointment with Defy to get a consultation and potentially start a TRT protocol to treat my low free testosterone. I looked back at my lab history over the past 2 years and I...
- BCD19800
- Thread
- Nov 29, 2018
- defy shbg
- Replies: 5
- Forum: Testosterone Basics & Questions
B
High SHBG

Hi all, I’ve been treating hypothyroidism over the last 2.5 years and finally after multiple medications and doses i’ve found what works well for me. I take a combination of unithyroid and cytomel along with some iodine. Unfortunately, since I started my treatment, my SHBG has been...
- BCD19800
- Thread
- Nov 26, 2018
- low free testosterone shbg testosterone
- Replies: 62
- Forum: Testosterone Basics & Questions

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038