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Many people in the anti-aging world have heard of the experiments done by the team of Mike and Irina Conboy which involved putting the blood from young mice into old mice and vice versa. In summary it showed that the old mice showed signs of getting younger and the young mice showed signs of...

The linked video has IMO a lot of great points that everyone who follows the developments in this area should be aware of. It's very relevant for the IMO over-rated concept of calorie restriction and the anti-Growth Hormone arguments, and lots of other topics as well:

I just finished reading the book The Salt Fix, and it addresses many topics which have come up in various threads here so I am posting some highlights, along with a few other items not covered in the book. The book has been out about ten years and I have heard many podcasts with the author, but...

Here at Excelmale there are frequent posts discussing the pros and cons of statins, and one in particular several weeks ago where a position paper was cited where the assumption was that statins are not only a viable option but should be the first line of defense against heart disease. As I have...

FDA approves new treatment for hypoactive sexual desire disorder in premenopausal women PT-141 AKA Bremelanotide AKA Vyleesi approved. This should open up a whole new focus on the melanocortin system and allow for crowdsourcing the best dosing/timing. It seems something good is happening in...

Every few months or so, a post seems to come along saying something along the lines of “should I do PRP or Stem Cells or Nandrolone or anti-inflammatory injections or [insert something exotic here] for joint issues”. While all of these and others likely have their place, they are often either...

High-dose Niacin was generally considered very beneficial before about 2010 but then fell into a bit of disfavor without much credible change in the science. I have been watching the evidence for a long time and it seems incomplete but generally positive. I have tried niacin on and off without...