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    Creatinine & eGFR

    As I feared would happen, my creatinine and eGFR levels are getting worse while on even low doses of testosterone. 02/12/2021 pre-TRT Creatinine 1.10 ML/MIN/1.73, 0.80-1.40 eGFR African American 93 ML/MIN/1.73, >60 eGFR non-African Amer 81 ML/MIN/1.73, >60 11/06/2021 pre-TRT Creatinine 1.36...
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    Worsening Symptoms, "Dead Penis"

    Instead of taking Defy's dosing advice, I tried going "low and slow" for six weeks, but my libido and sensitivity completely dried up after a couple of weeks. Defy had recommended 100 mg T cypionate/week, divided into three doses, but I went with 10 mg/daily. They have also recently added hCG...
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    How To Use Defy/Empower Nasal Gel Pen

    I received my first nasal gel pen in the mail from Defy today, but it came with no instructions on how to actually use the pen. The only moving part is the rotating clicker at the bottom. I rotated it fully (several clicks), but nothing came out the dispenser. There is no pump or any other...
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    Acceptable Air Bubble?

    No matter how I try, I am always left with a tiny air bubble. I ever so slightly overfill beyond my intended dose to make up for it. Should I be aiming to have zero air bubble in the syringe? I've included a pic of the air bubble in my 10mg daily shot.
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    Should I Be Worried About My Blood Pressure On TRT?

    I'm hypertensive with blood pressure usually measuring about 130/90, but my PCP hasn't put me on any medication. I started TRT a week ago with low dosing. Wondering how cautiously I should proceed here.
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    When To Test For Peak Or Trough

    How many hours after I inject cypionate would I test the highest? How many hours before the injection would I test the lowest? Is it as simple as just before the next injection? I am on an EOD schedule.
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    Starting HRT, Mainly for Libido

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    New Guy Looking For His Libido

    Hi, I joined here because I found so much info here on how DHT helps libido. I was on injections. I gained 20 lbs of muscle on low dose cyp, but no libido. Just added transdermal to scrotum to up DHT as of yesterday and waiting for results. Already having sex dreams and night wood, but no...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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