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    Low SHBG Success Story - Almost 4 Years of TRT

    I know there are many low SHBG posts and most are negative for the most part. I wanted to share some things that I have learned through some experimentation over the last 4 years seeking more libido that have helped me dial some things in to my current protocol: 19mg T-Proprionate ED .25mg AI...
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    Trimix/Bimix - Corpus Spongiosum and Glans Issue

    I've used Trimix and Bimix off and on for the last year. I see so many posts about the raging 18 year old erection that many get and I want to see if I am the only person with this particular issue. I get a very full corpus cavernosum and nothing in the way of a fill in my corpous spongiosum...
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    Low SHBG - Lower Total T and Feeling Great

    Any other low SHBG guys feel better with a lower Total T? My current numbers are: Total T: 428 ng/dl (240-950dl) Free T: 14.1 ng/dl (4.65-18.1) SHBG: 18 DHT: 653 pg/ml (112-955) E2: 27 pg/ml (10-40) I used to always be on the higher end of Total T and Free T was through the roof from higher...
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    Low SHBG but normal SHBG Pre TRT

    Hi all, I know there are countless low SHBG posts but I felt the need to start another. Are most of us normal SHBG before TRT? Does that matter in any way? I am thinking of drastically cutting back my dosage as my free T is consistently high. I have had Total T almost to 1000 with a similar...
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    Daily Injections - Sinking Total T?

    I am a lower SHBG guy and have resorted to daily injections. My last lab showed a major dip in Total T and I am now at 510 ng/dl. My weekly dose has not changed but is broken out into daily injections. My protocol is: 23mg Test-c ED 1 click of 20mg/ml Test Cream on scrotum for DHT .5mg AI ED...
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    Low SHBG and Free Estrogen Impacts?

    Yes I know..yet another low SHBG post. I have been googling and searching this forum and can't find anyone referencing lowish SHBG and the relationship to free estrogen. My Dr. says I am a hyper-metabolizer, hyper-excretor and hyper-converter to estrogen. Seems like a bad trifecta! My Pre-T...
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    Anyone inject Phenylephrine HCL for priapism?

    Hi All - Has anyone injected Phenylephrine as referenced in Nelson's post ? I have some arriving on Friday from Empower and want to know dosage and needle size that anyone would recommend. I am hoping to not need it but if I do I am hoping that I can use my same 30 gauge insulin pins that I use...
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    TRIMIX Dosage Forum

    So I've tried Trimix 5 times with varied results. This is the standard 30-10-1 mix from Empower. Attempt 1: 5 units (.05ml) decent erection lasting around a half hour. Attempt 2: 8 units (.08ml) resulting in an ER trip and an erection around 8 hours. 120mg Sudafed did nothing. Urologist in ER...
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    4 Months In - No Improvements - Major E2 Issues - Switching to Defy

    I am 4 months in with TRT and have yet to feel/experience any benefits. Please, please look at these labs and let me know your thoughts. And let me know if you have any questions. I am moving to Defy and have my first consult with Dr. Saya in early January. My doctor now is recommending I...
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    Struggling EOD Protocol - Low TRT Levels?

    I have been struggling to get better and am on week 9 of TRT. I started with 70mg E3.5D and 200IU HCG EOD for 6 weeks and ran into major E2 spikes. I am currently looking into switching to Dr. Saya at Defy as I am hoping to dial into something that works. Please see my progression below, I am...
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    Introduce an AI or Dosage Adjustment?

    I posted a few weeks back about having no benefits of TRT after a few weeks in with a protocol of 70mg E3.5D and 200IU of HCG EOD (HCG only started for the last 2 weeks..and I had no effects of 4 weeks TRT without it). I am now in my 7th week, still with no effects. My libido and erections are...
  12. R

    5 Weeks Into TRT and Feeling No Effects? Need libido ASAP. Please help

    Hello - Many month lurker and first time poster. I discovered I had low T in early June of this year after mainly symptoms of almost no libido, brain fog, ED, no gains from working out. I am 35, fairly fit at 6'2" 198lbs and previously did cardio 5 days a week and have since quit that and have...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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