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https://www.amazon.com/Perfect-Fitness-Multi-Gym-Doorway-Portable/dp/B008DNAJYI?ref_=ast_sto_dp&th=1 I've been using this for six or seven years. No complaints. I don't trust the door trim to hold it though. Got a 1"x3/4" piece of white PVC trim board. Cut the length of the of the top door trim...

Lexapro can possibly effect cortisol testing. Am I correct in guessing that it hasn't helped with the lethargy? OpenEvidence: Escitalopram can affect cortisol blood tests. Multiple randomized controlled trials and clinical studies have demonstrated that escitalopram, a selective serotonin...

Am I understanding this correctly? 8am cortisol was 10 ug/dl, then at noon it was still 10 ug/dl? What time do you normally wake up? If you normally wake up around 4am then it may be normal. Noon cortisol should be somewhere around 1/2 the morning cortisol level. A flat cortisol curve can be...

This is from OpenEvidence: Glucocorticoids—including oral, intravenous, inhaled, topical, intra-articular, and intranasal formulations—are the medications most commonly associated with disruption of the normal daily cortisol rhythm. Chronic or supraphysiologic dosing suppresses the...

https://pmc.ncbi.nlm.nih.gov/articles/PMC5563520/

My 2 cents, I agree that sounds low. Are you taking any glucocorticoids like Hydrocortisone, Prednisone, Triamcinolone? Azole antifungals? Opiates? I'd test cortisol at 8am along with ACTH. Anything under 10 ug/dl at 8am, especially with low or low normal DHEAS, then I'd pursue adrenal...

Forgot to mention, This is meant for ME/CFS, but I think it's a really good comprehensive fatigue workup in general. https://mecfscliniciancoalition.org/wp-content/uploads/2021/05/MECFS-Clinician-Coalition-Testing-Recs-V1.pdf Also, to you original question, If it were me, I'd would give it 3...

Post exertional malaise is usually what distinguishes ME/CFS from other types of fatigue. PEM can be exacerbated by physical, mental, and/or emotional exertion. Basically, if you work out too hard or do too much (physically or mentally) do you crash for a week? This is a good review...

Thanks for the reply. Interesting, I just checked my discountedlabs.com order from September of last year. This is the test I ordered copied and pasted from the invoice: Testosterone, Total ( LC/MS), Free T (Equilibrium Dialysis), Bioavailable T, and SHBG The results showed the 46-224pg/ml...

Just curious if anyone knew why they changed the reference range? The reference range used to be 46-224pg/ml for free testosterone by equilibrium dialysis. In 2025 it changed to 35-155pg/ml. That's roughly 1.4% of the total testosterone reference range (250-1100ng/dl). 1.4% of 250 is 35. 1.4% of...

From the Mayo Clinic link in post#15 "we recommend that interested health care professionals view the ME/CFS Treatment Recommendations document published by the US ME/CFS Clinician Coalition." LDN listed under the pain section...

Low-dose Naltrexone Improves post–COVID-19 condition Symptoms Dr. Younger is the director of the Neuro-inflammation, Pain and Fatigue Laboratory and is also a member of the UAB PAIN Collective...

Diagnosis and Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome https://www.mayoclinicproceedings.org/article/S0025-6196(23)00402-0/fulltext LDN is listed several times in the table of management options

Have you ordered from them recently? I just called, 855-427-4682, and was quoted $390 for a cash price, also said they don't accept goodrx or anything like that. https://www.optum.com/en/customer-support/pharmacy-support/specialty-pharmacy-customer-service.html

Is this the same Optum you order from? https://www.optum.com/en/customer-support/pharmacy-support.html 855-427-4682 I just called to transfer my Rx from Walgreens and was told Pregnyl 10,000IU was $390, she said they didn't offer a generic and gave me a # for Organon patient assistance to see if...

If they increased after the cypionate and milk thistle: Reputably sourced cypionate? When did you start the milk thistle and is it a tested product? AST:ALT ratio is <1 in both tests https://en.wikipedia.org/wiki/AST/ALT_ratio What's the ALT lab range? Typically around <45 is considered...

I think we agree on more than we disagree: poor diet, environmental factors, social media, etc. are all factors in depression. Antidepressants aren't perfect but I wouldn't trash them on a whole. Meds helped give me the ability to address diet, exercise, sleep hygiene, etc. that I didn't have...

It's definitely a concern, and for sure it's frustrating for all parties involved. If you're passionate about the prescribing of antidepressants, I suggest calling your senator and house representative because I believe it will literally require an act of congress. From what I understand: 1)...

Reminded me of 2 times that I experienced something similar: 1) Are you taking generic Adderall XR? I ask because I noticed fatigue, anxiety, and a bunch of weird stuff when my pharmacy changed brands of generic Adderall XR due to a supply shortage. I didn't think there was a difference in...

Is it seasonal by any chance? I'm not a psychiatrist, but from my own MDD experience I'd recommend a PHQ-9 first. See if you're barking up the right tree. For depression meds, some people respond really well to serotonin meds like SSRI's (also the studies on serotonin agonists like psilocybin...

https://www.aafp.org/pubs/afp/issues/2024/0600/testosterone-replacement-therapy-male-hypogonadism.html I emailed the author of the 2024 American Family Physician guidelines. I also CC'd the AAFP, the Endocrine Society, and the author of the 2017 AFP guidelines. He responded that he received my...

As far as this stuff goes, we live in a really cool time. The price of Whole Genome Sequencing WGS is becoming more affordable. I came across this list for anyone that's interested. Average price I've found for 30X WGS is around $400-$500. https://arep.med.harvard.edu/gmc/genome_services.html...