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I have been on topicals, pellets, and injections. Of the three, injections were the least effective. My libido dropped like a stone and never recovered, even going to twice a week injections. It made zero sense to me to inject daily when I could just use a topical. I am a low SHBG diabetic...

Is that from EmpowerRx?

I have been thinking about switching to compounded testosterone cream. However, unlike injectable testosterone cypionate and topical/gels generic and brand name, compounded testosterone is probably not covered in my prescription coverage. Does have anyone have an approximate price for 30ml of...

Testostorone manufacturers do have recalls. Cipla had a recall in 2019. Dr Reddy's, Cipla arm recall drugs in US market

My girlfriend is an RN. She injects me IM into my glutes, alternating sides.

The brand is Cipla, which I believe is an Indian generic manufacturer. Anyway, my doctor decided to adjust my dosage and retest. I was on a higher dosage and doing well blood test-wise, but I was having issues with my blood pressure that turned out to be unrelated to testosterone, so I scaled...

My hemocrit was in the low 40s when my TT was okay. It is pushing 50 now.

No doubt! I was shocked when I saw my posted lab results. I may have received a bad batch of testosterone.

Actually, that is the problem. My testosterone never reaches 1500 two days after injection, not remotely close. I was 249ng/dl two days after injection. It is like I injected a placebo instead of testosterone cypionate. That is what is confounding. My total testosterone used to be reliably in...

That does not sound good for me. I was put anastrazole in the middle of last year, so your analysis sounds right. However, to be honest, I am never going to inject daily. I would rather go back to using topical. I did not have the hemocrit problem on topical and my testosterone level was...

I have been on injections since 2019. I inject 100mg of testosterone once a week. I have seen a steady decline my testosterone level over that last year. My most recent blood test was taken two days after my injection and my total testosterone was only 249 ng/dl. My total testosterone was in...

I switched from Androgel to generic Axiron before switching to pellets and then injections. I switched to generic Axiron because it is applied under the arms like deodorant. That is about as safe as one is going to get with a topical. If I had my choice, I would have stuck with pellets, but...

One thing I know about diet is that works is unique to the individual, especially when a person is dealing with a metabolic disorder. I am a type 2 diabetic who went on a whole-foods, plant-based diet against the advice of my endo. The ADA diet absolutely did not work for me. My endo was...

I suffered a massive rotator cuff tear eleven years ago. I experienced full thickness tears through the supraspinatus, infraspinatus, and subscapularis tendons and a 50% tear through the teres minor tendon. The labrum in glenoid cavity was also torn. The first orthopedic surgeon who operated...

That article is interesting. The reason why I originally discontinued TRT was because I underwent coronary artery bypass graft (CABG) surgery. A year after the surgery, I was still experiencing problems with ED medication being effective, so I asked to be put back on TRT, even though my free T...

My blood pressure (BP) has continuously risen since going back on TRT in the fall of 2017. I was on topical solution until Spring of 2019 when I went through a round of pellets before going on testosterone cypionate injections. My resting BP is now in the 170/100 range, and it can go to over...

That is clearly not a universal maxim. I experienced E2 problems with topical solution, but not pellets or injections (I went through a round of pellets before my urologist switched me over to injections because he was not seeing the numbers he wanted to see at the end of three months). I am...

Like I said, I could do it. I used to inject a diabetes drug when I was camping. It was a pain in the backside. I was never as happy as when I finally learned what worked for me diet and lifestyle-wise and was able to reduce my hbA1C to a point where I could just use metformin. As long as...

For me, it is about convenience. Even though many injectables do not need to be refrigerated, they are not conducive to certain lifestyles. For example, I like to fly fish. One of the areas I fly fish requires me to camp primatively. I would hate to have to inject myself while camping...

One thing that I would like to add is that my urologist's practice is not a closed system like Nelson discussed. The only thing that his practice handles is ordering the Testopel pellets. I purchase the compounded pellets directly from the pharmacy and all of my blood work is performed by LabCorp.

Trust me, I was worried about infections, extrusion, and scarring. I even voiced my concern to my urologist even though I requested to be put on pellet therapy. He did not push me to use pellet therapy. I paid the compounding pharmacy who made the pellets that were not covered by insurance...

I did not want to have to deal with syringes and a Sharps container. I was on injectable diabetes medication for a while. I hated having to deal with needles and injectable medication. Pellets are no fuss, no muss. I love not having to apply testosterone topically or inject it, especially...

That is interesting. I went on a combination of Testopel pellets and compounded pellets six weeks ago (my insurance company only covers six Testopel pellets). I reviewed my five-week test results with my urologist today. My total testosterone was 617, which is over 200 points higher than it...

I have been on CPAP therapy for 15 years. I have been through many masks in that time. My mask of choice is the ResMed AirFit P10 nasal pillow mask. The P10 is light years ahead of my first mask. I barely feel it on my face. Plus, the P10 diffuses the air leaving the mask, which means that...

Obstructive sleep apnea (OSA) is one of several comorbidities I have to manage. I use CPAP therapy. I used to be much heavier with a higher pressure (14 cmH2O before, now between 9 and 10 cmH20, depending on level of congestion) . I have not noticed a huge increase in OSA symptoms since going...

There are a lot of guys who do injections that have experienced a rollercoaster ride. Every person is different; therefore, every protocol is different. I am not doing daily injections, period, end of story. I would rather suffer low-T symptoms. I am no stranger to daily injections. I was on...

She does not want to be in the business of managing TRT protocols. Her specialties are thyroid and diabetes. She is primarily my diabetes doctor. TRT came in response to me hot flashing in her office one day several years ago. TRT was about alleviating low-T symptoms, not optimizing how I...

I decided to turn TRT treatment over to a local, well-respected urologist who specializes in male sexual health from my endocrinologist. He looked at my labs and said that my endocrinologist was doing the bare minimum she needed to do with respect to treatment and that my valley was too low (I...

A fasting glucose of 5.1 mmol/l is non-diabetic, but it is not ideal. Ideally, you want it to be under 5.0 mmol/l, which translates to 90 mg/dl (our glucometers display mg/dl reading in the U.S.). Most people without insulin resistance have a fasting blood glucose level lower than 90 mg/dl. I...

Low SHBG goes hand-in-hand with insulin resistance. I am a type 2 diabetic. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680959/pdf/ec-02-18.pdf

All I can say is that having low SHBG makes TRT tricky. My SHBG is in the twenties, and I have pretty much given up for the time being. Things are great during the honeymoon phase, but the side effects make managing replacement challenging after one has transistioned through that phase. There...