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Oh, nothing personal! Was wondering, if all men on trt would take hcg, how many pregnant women would we need to harvest for hcg per year. The whole pee aspect makes me feel uncomfortable. Luckily we have India I'm hoping for an esterified version of lh

Happy hunting my friend

According to DeepSeek you need about one pregnant woman per year to harvest your hcg. 80L of trimester urine for 52k IU ### The Standard Yield - **1 liter (L) of first-trimester pregnant urine** → Yields **≈1 mg of purified hCG** after industrial processing. - Since **1 mg hCG ≈ 650 IU**, this...

If I knew what my normal healthy level was before it crushed to about 150, that would be the reference value of my natural physiological T level. Unfortunately most of us do not have this datum. What can we do? We use the population normal distribution as reference. I would use the population...

Yes, it works for you. Perfect. I'm not judging, how could I based on the scarce scientific data. Table 2 baseline T levels: mean +- SE. There is variation between individual baseline levels. There is no need trying to justify your dose. At least not from my perspective. It's not about the...

My comment was about the (mis)interpretation of the study. Sticking to science and not making up things and jumping to conclusions that are not supported by the data. Everyone is obviously allowed to share his opinion and encouraged to share his experience. Everyone is free to experiment and...

Exactly that. If anyone cares, look at the baseline peak levels. Table 2 and table 7 for hemoglobin and hdl. This work did not aim to find the TRT dose for the study population. Read the discussion, limitations etc.

https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.16612 Abstract Aims Nearly 42% of adults in the United States have obesity, a significant risk factor for many cardiometabolic diseases and cancers. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are promising...

I give up! AI succeeded humans in reasoning... I apologize for being rude. It's just so frustrating.

"My priorities are I want to keep the ability to perform in the bedroom, at the gym and not go through life having zero energy, brain fog, 2nd guessing and able to make a decision on anything." = TRT But that's not what you want: "Compared to where I was. 500ng/dl is amazing. But I don’t have...

Especially if one aims to prioritizes brain/mental health.

https://journals.physiology.org/doi/full/10.1152/japplphysiol.00276.2025

This comment was financially supported by The FunkOdyssey Makeover Clinic

I should have written that this comment is not related to your discussion (more to Vince's post and in general there is often a bias towards physique). I was amazed how long you both discussed in a civilized manner. Bravo Yes, I think to know that there is dose relation to symptom relief...

Yes, a personalized approach. If we look at the normal distribution and taking TRT literally, I agree with @Cataceous though. The aim of TRT isn't 'supraphysiological' muscle growth.

Interesting

I disliked the misinformation and outcasting and making feel people guilty if they considered not taking a COVID vaccination.

Any reason YOU (18yrs) would need to take any of these drugs?

Would then only change one variable, i.e. reduction of the dose from 60 to 50.

Did you feel any different with twice per week injections?

", I still have the phenomenon a feeling sort of bad the day after the injection and always feeling the best to wear the end of the week. " Yes, it makes sense to me to split and to reduce your dose. And you could try testosterone undecanoate. Once per week injections give very stable levels.

https://www.midwesterndoctor.com/p/we-now-have-proof-the-covid-vaccines

Being now on TRT, you could try losing bodyfat without additional drugs. TRT should make it easier keeping muscles while dieting.

Great, could you please send me a kit :) Here minimum 85€ for 5mg

"Increased joint pain in prone sites of tendinopathy (shoulders, elbows)." Did your strength and workload increase (faster) since adding TRT?

"The biggest benefits I’ve seen are I have lost about 12 pounds, but the weight loss has plateaued over the last month. I’ve also seen really good body composition changes for it only being two months, as I am lifting weights 3 to 4 days a week." "My libido has not been very good, and I am...

I think that if one applies the cream twice daily, keeping levels stable that it will raise hct almost as high as with injections when the accumulated T dose is comparable.

What was your TT or fT on this 42mg TC per week? Hope the cream works for you wrt not raising hct (too much).

I would consider anything above the age related reference range supra physiological. If my age-related max TT is 750, and I have a constant level of 750, that's also supraphys

Bone microstructure matters https://pubmed.ncbi.nlm.nih.gov/19783591/ https://open.oregonstate.education/aandp/chapter/6-3-bone-structure/

It can be a medication in high doses for bipolar. Here in this context it's about supplementing single digit mg (about 1mg). We have various small amounts in our water etc. So far lithium is not regarded essential but there is academic discussion about it and whether a small amount is...