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The nebido protocol. For oral TU the data is then probably based on once daily protocol, resulting in less accumulated fT over the day and enough time to clear E2.

Why the difference between TU and TE/TC? What dose and injection intervall? When topical is mentioned it probably means Androgel. Not the same as twice daily high percentage Testo cream. Etcetera You provided a much clearer correlation, i.e. accumulated free T. Oral TU is outstanding. Why...

It's about Erythrocytosis. Maybe treat based on symptoms vs treat based on numbers. I recall an earlier study which linked E2 to Erythrocytosis, and it employed AI to manage it when E2 was high on modest TT levels.

The following article was cited: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c02039 Finasteride, a 5-alpha reductase (5α-R) inhibitor, is a widely used drug for treating androgen-dependent conditions. However, its use is associated with sexual, psychological, and physical complaints...

What about dessert?

They should not misinform and mislead people.

Can you take about 4 weeks vacation or long-term cut your work hours in half? Can you take 2 months pause of fin? I guess your idea is that TRT gives that boost that would balance out your work stress. Maybe it would help (short term). Only opinions here, nobody can know for sure what's the...

Did you try magnesium supplements?

Yes. Your body will adjust. Maybe later you can tolerate more T and maybe it would give more benefits then.

Have recently added Q10 (mitochondria energy) and Rhodiola Rosea (dopamine).

Did anybody try dopamine nootropics? They usually have a short halftime, thus supposedly no interference with sleep. Rhodiola rosea, modafinil?

HGH makes me tired. Some use it before bedtime for better sleep.

Funny And probably no placebo effect with horses I took it 3 times per day. I think it reduced inflammation.

It helped me with knee pain.

What supplements have helped you?

https://www.cambridge.org/core/journals/psychological-medicine/article/comparative-efficacy-and-tolerability-of-nutraceuticals-for-depressive-disorder-a-systematic-review-and-network-metaanalysis/5799A126D0B5677764562824C452D545 Abstract Background Nutraceuticals have been taken as an...

Imo your hct was still good. I do not recommend you do blood donation to reduce your hct. Did you have any symptoms possibly related to hct?

IMO you have a very good absorption with SC injections. Imo your shbg looked better with 80mg. Could do 3x/w SC to achieve a higher trough level. That would get you closer to your magic number... You should include hct in your labs!

https://pmc.ncbi.nlm.nih.gov/articles/PMC6676071/ Figure 1

So true. Had here discussions about androgel T level dropping to the end of the day. One member here kept on posting studies that show that levels are stable. Finally evidence accumulated and serum tests showed differently. It wasn't only me... That 10-20% 'outliers' often get 'averaged out' in...

Estrogen does increase prolactin and elevated estrogen can move balance towards less dopamine. @LookingForAnswers

Could be bit higher or bit lower. If you want to know for sure you would need to take blood several times the day to get an estimate of the daily variation. It might differ slightly from day to day. It really doesn't matter. I'm afraid the question was initially asked with malign intend stemming...

I noticed the timing too and thought about it. In my experience the SQ gives a delayed and flattened response. No idea when there would be a minor peak during the 24h window. Maybe we can agree that next time he measures before the injection. I really don't expect any relevant difference. Don't...

It's SQ and daily. Would be nice to have a 24h graph of T level in general but that's not the purpose here.

You are right about your prolactin being only slightly above range. Also opinions vary about T optimization. Imo the information about your nutrition might be crucial. I recommend you try cyclic keto including 1-2 days per week where you eat 'normal' reloading on carbs. Did you get a test for...

Good starting dose and good starting level achieved, good absorption with SQ. You could wait few more weeks and let things settle, you might start feeling better on that dose/level. Imo an increase of about 10mg per week would be a good choice.

No, never got the RT3 from my GP. I meant your mental symptoms. It felt like the benefits of the morning 6ug T3 phased out or I got used to it. Maybe I will try again. Partial cold shower in the morning after my normal shower has had positive effects. Eating a small breakfast instead of only...

If that's the goal, I would need about 250mg TU per week. One SQ injection at glute region. No problem. Oral or topical requires even much more T and money. That's not the point here, right? I thought only the sudden lower E2 is the problem. Now that I understand your intention, it makes sense...

Could just inject more SQ if it's not enough. I don't think that SQ is generally wrong or inferior.

It's strange that your e2 is suddenly at the low end. IMO it's not necessary to inject ed when injecting SQ. I would go with eod SQ. What's going on with your wbcc and bilirubin?

I felt like elevated e2 had these effects on me. I know, not the whole E2 discussion again. Just wanted to mention it to you. Adding a bit T3 in the morning helped for a while. I think the whole hype that TSH should be below 2.0 is nonsense.