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  1. Vince

    VO2 Max: The Gold Standard

    AI Overview While both VO2 max and strength are strong indicators of longevity, VO2 max is considered the most robust predictor. However, strength, alongside muscle mass, plays a significant role in overall health and lifespan. VO2 Max: The Gold Standard Definition: VO2 max, or maximal...
  2. Vince

    Dosages

    Exactly we are all different and need different levels. You should read Florence's book I think you would find it very interesting and educational.
  3. Vince

    Dosages

    Calm down
  4. Vince

    Dosages

    https://www.excelmale.com/threads/why-do-some-men-need-supraphysiological-doses-of-testosterone-to-achieve-normal-levels.32512/post-298802
  5. Vince

    Dosages

    I say would say a good starting dose would be 50 mg of T and 500 IU of HCG combined in the same syringe. My understanding is that's @Nelson Vergel protocol. Here's mine. I just had Labs done yesterday will post when available...
  6. Vince

    Dosages

    No. What I mostly see is younger men need lower doses. The reason behind it is when you were at your peak. What was your T level at. Most younger men had lower levels when they were at their peak. Older men had higher levels when they were at their peak, so now the older men need higher levels...
  7. Vince

    Testosterone dropped after a few months on the same dose

    Your first labs were done after 8 weeks. Not long enough. You need to wait at least 12 weeks. So your 2nd Labs I would consider more accurate. Every time you do Labs they will vary. Injecting is not 100% accurate and of course vial strength will vary. I feel my best at higher levels so I see...
  8. Vince

    Reassessing the evidence of a survival advantage in Type 2 diabetes treated with metformin

    https://www.sciencealert.com/common-diabetes-drug-linked-to-exceptional-longevity-in-women
  9. Vince

    Clomid for Testicular Shrinkage ?

    I now inject 500 IU of HCG every third day. I combine T and HCG in the same syringe, like Nelson. It's not true about desensitization.
  10. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    That's exactly what Florence Comite talks about in her book and practice. https://en.m.wikipedia.org/wiki/Florence_Comite
  11. Vince

    Does arthritic elbow mean I can't lift weights?

    This is what worked for me. Of course it may not work for you. I had tennis elbow about 3 years ago, it was very painful. I had to resort to pull-ups and chin-ups really stretch out my elbow. It did work for me. Now I'm completely pain-free.
  12. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    AI Overview Based on the provided search results, the UGT2B17 gene plays a significant role in testosterone metabolism and clearance, specifically through glucuronidation, a process that makes testosterone easier to excrete. Individuals with a deletion in the UGT2B17 gene show reduced...
  13. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    CYP17A1: This gene plays a role in the synthesis of testosterone.
  14. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    https://www.excelmale.com/forum/showthread.php?1403-Are-you-a-fast-metabolizer-of-medicines&highlight=Fast+metabolizer
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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