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  1. FunkOdyssey

    American men are hungry for injectable T: A legion of new health clinics are serving it up

    I will take him seriously on this when he posts his labs and they are not also found to be "absurdly high". I am reminded of the closeted gay congressman that publicly rails against homosexuality until they are caught in a men's room sex act.
  2. FunkOdyssey

    starting injections soon a little nervous

    I mean subcutaneous injections work well for 60-70% of men who try them: As I stated earlier, you would begin with IM if you wanted to maximize your odds of success right out of the gate.
  3. FunkOdyssey

    starting injections soon a little nervous

    Good luck. This works well in maybe 60-70% of men.
  4. FunkOdyssey

    starting injections soon a little nervous

    If you want to maximally reduce the possibility that some aspect of your injection site and method interfere with your results, I would suggest IM injections into delts or ventroglutes with these specific 5/8" insulin syringes: Easy Touch U-100 Insulin Syringe with Needle, 27G 1cc 5/8-Inch...
  5. FunkOdyssey

    Blood panel, how's mine look?

    How did this feel? I would think this, with some daily hCG added to bump the numbers up a little and fill in some gaps, ought to be a decent protocol for you. Look at you! Very impressive sir - not much room for improvement here. Still, give the 5/8" needles a shot (hah) if you ever return...
  6. FunkOdyssey

    Indirect way of monitoring E2 without blood test?

    You don't care about E2 numbers but are trying very hard to keep your E2 at a specific number. Got it. No, I've never seen it used for this purpose before. Metformin is a cutting edge adjunct in the TRT space. Let us know what happens if you try it.
  7. FunkOdyssey

    Blood panel, how's mine look?

    I would suggest the second statement follows from the first. Excessive E2 has anti-dopaminergic effects via at least three distinct mechanisms: disinhibited prolactin release (prolactin reduces DA synthesis and firing), downregulation of D1 and D2 receptors, and a serotonin/GABA crosstalk...
  8. FunkOdyssey

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    Looks like the lack of DHT raws caught up with alphagels, and they don't have the integrity to stop selling it.
  9. FunkOdyssey

    Feeling pretty sick following this mornings shots ...

    I concur with the others: I would restart with T alone, no hCG, no AI. The prominence of the doctors you consulted with, and your weight, are immaterial with regard to how you should approach this to optimize your chances of success and health outcomes. The difficulty of dialing in rises in...
  10. FunkOdyssey

    Indirect way of monitoring E2 without blood test?

    Also, please watch this video (my goal is for the entire TRT-using population to watch this video):
  11. FunkOdyssey

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    It's probably fine for many purposes as a TRT adjunct. My friend is only able to use .25 ml of the alphagels product every other day because it's so potent, and testing suggests that is only ~10% DHT.
  12. FunkOdyssey

    Indirect way of monitoring E2 without blood test?

    Your only hope of dialing in anastrozole is frequent bloodwork, and even that can be misleading, as the blood levels of E2 don't necessarily correspond to the effects of aromatase inhibition in tissues. Without the bloodwork though, your already low chance of success is reduced to pretty much...
  13. FunkOdyssey

    Indirect way of monitoring E2 without blood test?

    At-home test: https://www.maximustribe.com/lab-tests
  14. FunkOdyssey

    Building a TRT protocol around hCG

    I'm doing it - taking 150 iu daily right now, and if I have to drop something lower, it will be the testosterone. That's a far cry from running hCG alone or test suspension though, either of which will produce a 24 hr testosterone AUC that is somewhere close to my natty test AUC. Please don't...
  15. FunkOdyssey

    Testosterone Therapy in Pre- and Post-Menopausal Women: Deep Dive

    The decay rate of her follicles is the determinant of ovarian failure and it doesn't seem to matter whether you are stimulating them and releasing them or not. Their lifespan seems relatively fixed and finite either way (and is only about half of the woman's lifespan, strangely). I just read 4...
  16. FunkOdyssey

    Please check out my testosterone test results!!

    That's all pretty normal. What you're missing that is really important here is SHBG, so you could calculate your free testosterone. You'll want to repeat the total T, and this time I would add SHBG, estradiol (ultrasensitive) and LH. Free T is basically all that matters for hypogonadal...
  17. FunkOdyssey

    Building a TRT protocol around hCG

    That probably would work pretty well, but I'm not prepared to give up the physique advantages of actual TRT just yet. Maybe down the road if nothing else works.
  18. FunkOdyssey

    Testosterone Therapy in Pre- and Post-Menopausal Women: Deep Dive

    Possibly for someone younger. I wouldn't think it would be too effective as you approach ovarian failure (and not at all effective afterwards).
  19. FunkOdyssey

    Testosterone Therapy in Pre- and Post-Menopausal Women: Deep Dive

    Crucial point here. Giving my perimenopausal wife TRT only without estradiol did not work out well long-term. It gave her a strange mix of libido at times, combined with pain/discomfort during intercourse due to lack of estradiol.
  20. FunkOdyssey

    Building a TRT protocol around hCG

    Wow! Let me get this straight: you added 250 iu EOD to a protocol that otherwise would produce 10-20 pg/mL e2, and your E2 is now 86 pg/mL? If so, that's the craziest hCG e2 spike I've ever heard of. And yeah, that could certainly explain the loss of libido and moodiness. What effect did it...
  21. FunkOdyssey

    Switched from Testosterone troche to SQ shots, feel horrible now.

    Same here
  22. FunkOdyssey

    Building a TRT protocol around hCG

    So far, there have been some windows of improved libido, that have varied between a few hours to most of a day. I have no idea. It seems like most of the people who benefit from hCG use it continuously, although I've heard at least one anecdote where it only worked when cycled. I know what...
  23. FunkOdyssey

    Building a TRT protocol around hCG

    DHEA can raise it somewhat. The most reliable method is to supplement E2 directly though, crazy as it sounds. Your clinic will almost certainly help if you want to go that route, or you can procure it yourself from sources that cater to the trans market: Home - DIYHRT.Market I like injections...
  24. FunkOdyssey

    Building a TRT protocol around hCG

    Just to be clear, I'm not advocating for abnormally high estradiol levels. When I was talking about honesty around trade-offs, I meant being clear-eyed about the likely damage of inhibiting aromatase. Some people have the idea that if you modestly and carefully inhibit aromatase, just the...
  25. FunkOdyssey

    Switched from Testosterone troche to SQ shots, feel horrible now.

    Friends don't let friends start with subq. https://www.amazon.com/dp/B0CXF7V7BV 5/8" into the delt, ventroglute or quad. Lower dose isn't a bad idea either if your initial reaction is so unpleasant.
  26. FunkOdyssey

    Building a TRT protocol around hCG

    That's totally fair, as long as we are being honest about the tradeoffs we're making.
  27. FunkOdyssey

    Building a TRT protocol around hCG

    Please give this one a watch, and then tell me, in what scenario outside of possibly ER+ breast cancer are you going to improve anyone's health (man or woman) by inhibiting aromatase (even a little bit)?
  28. FunkOdyssey

    Building a TRT protocol around hCG

    Yes, that sounds plausible that it could, but inhibiting aromatase will not optimize for libido or health if these are important goals.
  29. FunkOdyssey

    Building a TRT protocol around hCG

    I don't understand how anastrozole brain penetration is relevant to our discussion, which has not been focused at all on anastrozole. What point were you trying to make? This approach to TRT protocol design is meant to optimize sexual function, not anabolism / body composition. Much higher...
  30. FunkOdyssey

    Building a TRT protocol around hCG

    In my case, and with my current SHBG of high 30's (as critical for context when interpreting E2 as it is for T), I think that translates to an e2 of less than 40. You don't actually need any labwork to determine that though. You would simply start with hCG at a target dose, start with...
  31. FunkOdyssey

    Help with blood test results and erectile dysfunction

    Berberine is very similar to metformin in its metabolic effects. I think it's reasonable to start with berberine and see how you do with that. I would probably experiment with metformin also at some point to compare effects and tolerability if you'll be using one of these long-term. With...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic

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