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  1. Seagal

    DHT: How High is Too High

    I find it strange that your lab report range would be ok with zero progesterone https://blog.healthmatters.io/2018/08/17/progesterone-in-men-definitionreference-ranges/ Seems like yours are optimal. In my lab report they calculated the ratio of progesterone to estradiol. Meaning hormone...
  2. Seagal

    DHT: How High is Too High

    Watch the video.
  3. Seagal

    DHT: How High is Too High

  4. Seagal

    DHT: How High is Too High

    I think truly impervious to serum DHT is muscle tissue. Not so for DHT derivates.
  5. Seagal

    DHT: How High is Too High

    Was thinking the same regarding progesterone: what is the proper level along with TRT. There is a correlation with age (up) and DHT (up) and progesterone & T (down). And I believe that serum DHT can reduce estrogenic activity, which is also relevant for skin hair follicles.
  6. Seagal

    DHT: How High is Too High

    I think to remember that if men were given DHT that it yielded reduced T levels. The question is what happens if that natural feedback loop is not working because of exogenous T.
  7. Seagal

    DHT: How High is Too High

    I'm not sure if there is a study that looked at elevated DHT in relation to T and hair loss. I can imagine that serum DHT can add up to the DHT produced within tissues. The experiments with DHT gel somehow show that serum DHT has an effect. That's similar to the claims about estrogen being a...
  8. Seagal

    Here for the science

    What did you publish? On what aspects are interested professionally. What is your background?
  9. Seagal

    Depression and carnitine (ALCAR)

    I should have never switched from ALCAR to tartrate CAR.
  10. Seagal

    Depression and carnitine (ALCAR)

    Here good red meat it's freaking expensive....
  11. Seagal

    Depression and carnitine (ALCAR)

    https://pmc.ncbi.nlm.nih.gov/articles/PMC8514700/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8964433/ "Several studies show that the level of acylcarnitines (ACs) changes significantly in patients with depression compared with healthy controls while the supplementation of acetyl-L-carnitine is...
    • Seagal
    • Thread
    • acetyl-l-carnitine (alc) carnitine depression
    • Replies: 3
    • Forum: Mental Health
  12. Seagal

    My blood test results on enclomiphene

    Did you take the blood test in the morning?
  13. Seagal

    TRT Numbers

    I only got 2 pumps prescribed. My TT was around 300 24h post application. Based on the age stratified TT levels, here they say everything is fine. .... We had here posts, where they measured after 24h and there was a big drop in levels, contrary to the studies. That's why I suggested to apply in...
  14. Seagal

    TRT Numbers

    This time apply the gel before your appointment in the morning. You could also ask to test your DHT, it might be just fine contrary to what others claim. It's not proven that one needs high end or above T levels for successful TRT.
  15. Seagal

    Strength, muscle mass, bone length, tendon insertion point

  16. Seagal

    Beard growth/face changes and TRT protocol - just me?

    Maybe the relevant difference is the level of estrogens. You probably didn't test it on both protocols?
  17. Seagal

    THC - indica for sleep?

    https://thecompleteherbalguide.com/entries/anxiety-stress/herbalguide-natural-sedatives/ One can get a tincture like tinctura sedativa. Also herbal drugs can have side effects, the effects are often milder than pharmaceutical drugs. If you cannot get good sleep, imo, it's better to use a...
  18. Seagal

    WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT

    How to manage hematocrit
  19. Seagal

    WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT

    @madman or @Nelson Vergel can you access the full article and maybe share some details? I cannot believe the statements in the abstract, e.g. I would think that any man would see an increase of hematocrit with TRT.
  20. Seagal

    Aromasin

    Probably best to act only if you have high E2 symptoms, especially if you cannot get the "sensitive" E2 test. @Nelson Vergel provides all the accurate testings. Unfortunately I cannot make use of his great service because I'm in Europe like you.
  21. Seagal

    Aromasin

    That sounds reasonable. Your TT is high, then your TE can be high too. Didn't your Dr recommend dropping the AI?
  22. Seagal

    TRT in men in their Nineties

    That's great! What @Cataceous wrote makes sense, it's reasonable. My gut says, if it's working smoothly, don't try to fix it. On the other hand, blood markers don't show the full picture. ... Then again, you are 93 yrs. For how long have you been on TRT?
  23. Seagal

    Advice About Hematocrit and TRT Dose

    One can inject e.g. 125mg of TU per week which results theoretically in the same hormone fluctuation as ED TC injections. Yes
  24. Seagal

    Aromasin

    Did you try without HCG? Not everybody needs it. Imo you could adjust your doses to achieve free T within normal range. E2 should then come down too and you could discontinue the AI. It's trial and error.
  25. Seagal

    Advice About Hematocrit and TRT Dose

    You didn't have these issue with nebido? I think to recall your initial posts here. Wonder if you would just have done fine with once per week injections of nebido.
  26. Seagal

    Advice About Hematocrit and TRT Dose

    Was your blood pressure increased?
  27. Seagal

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    Update on my 5mg Oxandrolone daily. For me the gym benefits lasted maybe 3-5 weeks. This diminishing returns seem normal for AAS cycles, however, I hoped with the small dose and the daily fluctuations the effects would remain. I was wondering if the same happened to you guys who do use TP...
  28. Seagal

    Anavar (Oxandrolone) Blood Levels Increased by Caffeine

    Immunoassay test?
  29. Seagal

    Anavar (Oxandrolone) Blood Levels Increased by Caffeine

    Thank you for the explanation of immunoassays. Didn't know that. Means I will pause taking Oxandrolone in order to obtain a reliable measurement.
  30. Seagal

    Anavar (Oxandrolone) Blood Levels Increased by Caffeine

    Yes, 125mg TU per week. It's a health blood check, not a sports doping test.
  31. Seagal

    Anavar (Oxandrolone) Blood Levels Increased by Caffeine

    @Nelson Vergel I'm currently taking oxandrolone and going to have a serum T test soon. Will oxandrolone skew the standard European testosterone test?
Buy Lab Tests Online
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic

Beyond Testosterone Podcast

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