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  1. Nelson Vergel

    The FDA is seeking your comments on black box warning for women's hormone therapy

    Review of the FDA meeting: What Really Happened at the FDA Menopause Panel - Excel Male TRT Forum
  2. Nelson Vergel

    The FDA is seeking your comments on black box warning for women's hormone therapy

    https://www.excelmale.com/threads/ashley-winter-md-calls-for-label-update-on-low-dose-vaginal-estrogen.32793/
  3. Nelson Vergel

    The FDA is seeking your comments on black box warning for women's hormone therapy

    The FDA is seeking comments on black box warning for women's hormone therapy The FDA is currently seeking public comments regarding the black box warning on women’s hormone therapy products for menopause. Here’s what you need to know: Background: Since the early 2000s, all estrogen-containing...
  4. Nelson Vergel

    Seeking Advice on Best Peptide for Muscle Growth

    When it comes to peptides for muscle growth, there are several options that research has shown to be effective, though it’s important to note that peptide use should always be discussed with a healthcare provider. The most commonly researched peptides for muscle growth include: Growth Hormone...
  5. Nelson Vergel

    Testosterone Cypionate - Carrier Oil Used By Different Companies

    Deep dive here: Comprehensive Analysis of Testosterone Carrier Oils: Formulations, Clinical Implications, and Emerging Developments - Excel Male TRT Forum
  6. Nelson Vergel

    Caffeine and its metabolites- Comparison

    More on caffeine : Molecular targets of caffeine in the central nervous system - Excel Male TRT Forum
  7. Nelson Vergel

    Caffeine and its metabolites- Comparison

    Here’s a comparison of Caffeine, Paraxanthine, and Theophylline, focusing on their structure, effects, metabolism, and common uses: Comparison Table: Caffeine vs Paraxanthine vs Theophylline Feature Caffeine Paraxanthine Theophylline Chemical Name 1,3,7-trimethylxanthine...
  8. Nelson Vergel

    Why we need muscle

    Further reading: Building and maintaining muscle for longevity - Excel Male TRT Forum
  9. Nelson Vergel

    Pros & Cons of 10 Surgery Types for Enlarged Prostate (BPH) - Which is Best for you!?

    More on treatments: How to Choose the Best BPH Treatment: UroLift, Rezūm, Aquablation & Expert Advice from Dr. Utsav Bansal - Excel Male TRT Forum
  10. Nelson Vergel

    Have had what was diagnosed chronic prostatitis for 15 years but turns out I now have severe LUTS and BPH at 44. Has anyone had success in treatment?

    You may want to read this: Pros & Cons of 10 Surgery Types for Enlarged Prostate (BPH) - Which is Best for you!? - Excel Male TRT Forum
  11. Nelson Vergel

    What Really Happened at the FDA Menopause Panel

    1. Why was the recent FDA hearing on menopause held, and what was its primary focus? The FDA held a long-overdue hearing on menopause due to a campaign by "Let's Talk Menopause" under the hashtag #unboxingmenopause. The primary focus was to address the black box warning on vaginal estrogen...
  12. Nelson Vergel

    What Really Happened at the FDA Menopause Panel

    Briefing Document: The FDA Menopause Panel and the Fight for Accurate Women's Health Information Source: Excerpts from "What Really Happened at the FDA Menopause Panel - Fempower Health | A Women's Health Podcast" by Georgie Kovac. Date of FDA Hearing: July 17th (Year not specified, but context...
  13. Nelson Vergel

    How to Lower High Hematocrit Caused by Testosterone Replacement Therapy (TRT)

    Very informative : Testosterone Therapy and Erythrocytosis - the most common dose-limiting effect of testosterone therapy - Excel Male TRT Forum
  14. Nelson Vergel

    Can Certain Blood Pressure Medications Decrease Hematocrit?

    Researchers conducted a controlled trial with 63 healthy adults (average age ~42, roughly half women). Each person did two test sessions—once taking valsartan (a medication that blocks angiotensin II type 1 receptors, called AT₁) and once taking a placebo (calcium carbonate), in random order...
  15. Nelson Vergel

    EXTENDED-RELEASE FORMULATIONS OF HUMAN CHORIONIC GONADOTROPIN (HCG)

    Here’s what I could piece together from publicly‑available sources: YearPublic milestoneDevelopment‑phase implication 2020International patent WO 2020/071912 published describing hCG‑loaded SynBiosys® microspheres and reporting only in‑vitro / animal data. Google PatentsPre‑clinical...
  16. Nelson Vergel

    EXTENDED-RELEASE FORMULATIONS OF HUMAN CHORIONIC GONADOTROPIN (HCG)

    @madman do you know when they it will be tested for an IND?
  17. Nelson Vergel

    TRT and stacking for weight loss

    I would definitely read this and listen to the podcast https://www.excelmale.com/threads/optimizing-fat-loss-and-muscle-preservation-tirzepatide-oxandrolone-trt-protein-exercise.32741/
  18. Nelson Vergel

    Walking 7,000 Steps Per Day Helps Keep Depression Away

    Although 10,000 steps per day, an unofficial target for decades without a clear evidence base, was associated with substantially lower risks for all-cause mortality, cardiovascular disease incidence, cancer mortality, dementia, and depressive symptoms than 7,000 steps per day, the incremental...
  19. Nelson Vergel

    Has or is anyone here experiencing PVCs (premature ventricular contractions)?

    I did. Got them fixed with ablation.
  20. Nelson Vergel

    What is the Optimum TRT Dose for Muscle Growth? : Nelson Vergel Reviews the Data

    FAQs on Testosterone Dosing and Effects What was the purpose and methodology of the 2001 study on testosterone dosing? The study, led by Dr. Bhasin and published in the American Journal of Physiology, aimed to determine the effects of different testosterone doses on young, healthy men...
  21. Nelson Vergel

    What is the Optimum TRT Dose for Muscle Growth? : Nelson Vergel Reviews the Data

    Briefing Document: Testosterone Dose-Response Relationships in Healthy Young Men Source: Bhasin, S., Woodhouse, L., Casaburi, R., et al. (2001). "Testosterone dose-response relationships in healthy young men." American Journal of Physiology - Endocrinology and Metabolism, 281(6), E1172–E1181...
  22. Nelson Vergel

    What is the Optimum TRT Dose for Muscle Growth? : Nelson Vergel Reviews the Data

    Landmark Study Reveals How Different Testosterone Doses Affect Muscle, Fat, and Health Markers in Young Men A deep dive into one of the most influential studies on testosterone dosing reveals key takeaways for anyone interested in hormone optimization—a topic of persistent debate in men's...
  23. Nelson Vergel

    Muscle gains on TRT vs overdosing

    125 mg per week is actually the magic dose. Read this: What is the Ideal Testosterone Dosage for Muscle Gain ? - Excel Male TRT Forum
  24. Nelson Vergel

    Pros & Cons of 10 Surgery Types for Enlarged Prostate (BPH) - Which is Best for you!?

    More details : Advances in Surgical Therapies for BPH - Excel Male TRT Forum
  25. Nelson Vergel

    The Link Between Muscle Quality and Erectile Dysfunction

    Briefing Document: The Link Between Muscle Quality and Erectile Dysfunction Date: July 21, 2025 Source: "Exploring the link between muscle quality and erectile dysfunction: assessing the impact of mass and strength" (Sexual Medicine Reviews, 2025) I. Executive Summary This briefing document...
  26. Nelson Vergel

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    I would stay on enclomiphene and use 500 IU hCG twice or three times per week, and drop everything else. Too many variables in your experiment!
  27. Nelson Vergel

    Pros & Cons of 10 Surgery Types for Enlarged Prostate (BPH) - Which is Best for you!?

    https://www.excelmale.com/threads/enlarged-prostate-learn-the-latest-in-minimally-invasive-options.27620/
  28. Nelson Vergel

    Pros & Cons of 10 Surgery Types for Enlarged Prostate (BPH) - Which is Best for you!?

    https://www.excelmale.com/threads/making-sense-of-bph-which-treatment-for-which-patient.30453/
  29. Nelson Vergel

    Understanding Testosterone Replacement Therapy and Managing Side Effects

    Short summary podcast:
  30. Nelson Vergel

    Understanding Testosterone Replacement Therapy and Managing Side Effects

    https://www.excelmale.com/threads/management-of-adverse-effects-in-trt.31833/
  31. Nelson Vergel

    Understanding Testosterone Replacement Therapy and Managing Side Effects

    What is Testosterone Replacement Therapy (TRT) and who is eligible for it? Testosterone Replacement Therapy (TRT) is a treatment for men with low testosterone levels. In the United States, insurance typically covers TRT for men with testosterone levels of 350 nanograms per deciliter (ng/dL) or...
Buy Lab Tests Online
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic

Beyond Testosterone Podcast

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