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  1. M

    Optimizing thyroid -- Resting Pulse? How to gauge for athlete?

    I just got some thyroid labs. I know normal ranges are not to be relied upon, but the range shows 9.2-24.1 so I'm not sure if single digits should really be the goal. By that logic, unless it's 9, you'd need to be below range to be in single digits. My latest labs were 12.5
  2. M

    Optimizing thyroid -- Resting Pulse? How to gauge for athlete?

    Hey LakeGuy81, you hijacked my thread! No worries, seriously. But still might be better to create your own thread to track your progress. I don't think Testosterone will effect resting heart rate. 2.65 TSH could be sub-clinical hypothyroid. I don't know about hashimotos and the antibodies...
  3. M

    Optimizing thyroid -- Resting Pulse? How to gauge for athlete?

    I'm almost 50 now and have been training - running, weight lifting for 25 years. I'm fit, probably 12% BF. I don't run long distances. I do a 20 minute trail run once per week and a few hill sprints at max effort on another day. I remember when I was in my 30s that my resting pulse would be in...
  4. M

    Too much B12?

    My HCT/Hemoglobin has varied much more than that just based on the day, how hydrated I am. I don't think you can ascribe the change to B12 levels... at least not without more data points.
  5. M

    Night sweats anxious and using anastrazole. Dosing guidance

    I got hot flashes when my E2 was low. As others said, spend the $50 and get tested :-)
  6. M

    Irritability and anxiety on Testosterone

    Skimmed the thread. Elevated H/H makes me irritable/anxious. The nurses pulling my blood told me it's common for people to feel relaxed after getting the blood pulled. You can get a double-red procedure where two pints are removed, centrifuged in a machine, then plasma and saline are added back...
  7. M

    Defy is selling Ibutamoren (MK-677) - anybody try it yet?

    I know this it a little OT, but am curious on your IGF-1 before and after arginine/citrulline? Also how much of these aminos you are taking?
  8. M

    Can Taurine Help Prevent Testicular Atrophy? Animal Data

    I read it's better to use surface area when estimating a dose across species. A simple practice guide for dose conversion between animals and human ResearchGate
  9. M

    Helping a man at risk of suicide

    I had a friend commit suicide in 2017 and feel/have thought the same way. I think if he had called me or I had called him how that day may have turned out differently. I empathize with you. It seems like we focus a lot on our physical health - muscle, BF%, lipid numbers, longevity, etc. It...
  10. M

    Elevated Hematocrit 61

    Make sure you are hydrated (and hydrated consistently) when getting tested. These values are sensitive to dehydration.
  11. M

    TRT without the use of Aromatase Inhibitors

    I think the Rouzier stuff has been taken somewhat out of context. The video is very long and I listened to about the second half of it. He has lots of studies which is appreciated. In what I listened to, the main points were: Studies showing disease correlated with high E2 levels were showing...
  12. M

    Liquid Arimidex - what liquid to use?

    I feel good on 0.1 mg EOD. I take 100 mg on Sunday and Wednesday = 200 mg/week I have tested E2 sensitive many times and adjusted based on those tests. Mark
  13. M

    Liquid Arimidex - what liquid to use?

    Vince, thanks, that was successful. The tablet dissolved nicely. I was able to get the tablet into a 1ml syringe and a total volume of 1ml including the Vodka and the tablet. I dispensed my 0.1mg dose and thought all was good. Today I look at the syringe and the tablet stuff (anatrazole and...
  14. M

    Liquid Arimidex - what liquid to use?

    I take a tiny amount of anastrazole -- about 0.1mg EOD. I have been cutting up the pills and measuring with a scale. My scale has become flaky and I'm thinking it would be more accurate to dissolve 1mg in 1ml of water and take it that way instead. Yes, I know I could get it compounded into...
  15. M

    Can not sleep on sermorelin help!

    This would be a subject for another thread. Biweekly dosing is going to have a big roller coaster for both T and E. A smaller dose more often seems to be the current thinking...
  16. M

    GH, IGF-1, Cancer - studies/data?

    Hi, I try to take in all of the data and make my own decisions. I've been thinking about adding a GH peptide and know about the benefits, but I have read that higher IGF-1 is cancer promoting, that we should strive for a lower IGF-1. I remember this being promoted by proponents of...
  17. M

    How to get legit peptides ?

    This reddit is "banned." Is there a new link or better info?
  18. M

    testosterone cause curly hair????

    I have had hair get more curly. I'd prefer for it not to be. If you find a solution that doesn't involve side-effects, please let me know :-)
  19. M

    What's the beef with anastrazole?

    KevinC - I got hot flashes when my E2 was too low...
  20. M

    T3, T4 and SHBG

    I read that thyroid meds can increase SHBG. Questions: 1. I have not found definitive info if it is the T4 in the meds or the T3 or both that cause this effect? 2. Is there any info on dose-response of Thryoid on SHBG? I'm being treated for hypogonadism (Cypionate 200mg/weekly +...
  21. M

    Biotin Interferes with Lab Assays

    Dr. Saya, if you had a list of supplements that you see elevating liver enzymes, it would be a useful thing to post. Thanks you, Mark
  22. M

    National Therapeutic Phlebotomy Program

    Some people can't donate for various reasons. The therapeutic phlebotomy is really the same as donating except the blood is discarded. There is also a "double-red" therapeutic procedure which uses a special machine to remove a pint of blood, centrifuges it and returns the plasma to you, then...
  23. M

    National Therapeutic Phlebotomy Program

    I might be misunderstanding, but... It would be nice if there wasn't a minimum 52 HCT, other than perhaps a minimum for safety. My reasoning is that if you're trying to maintain your HCT in a narrow band, say 45-48, you'd want to get a therapeutic when you're at 48-ish. Yes, doing it at 52...
  24. M

    Can someone be low T with natural levels in the low 600's?

    IMO - I think it would be better to try to fix someone with a TT of 600 without replacement first. Parts of your system are working OK. Maybe dealing with lifestyle and/or thyroid would fix SHGB and even bring up TT a little more. Replacement is a long-term commitment and requires some...
  25. M

    How to Prevent Non-Alcoholic Fatty Liver Disease

    Here is another study on NAFLD and dietary interventions using Serine and others. http://msb.embopress.org/content/13/3/916
  26. M

    IGF-1 levels low - how to boost?

    Gene, My DHEA-S is bottom of range and my IGF-1 is 110. I ordered up some Fountain of Life Micron5 DHEA Ultra Micronized DHEA 25 mg 180 sr tablets made by McPherson. I'm on T-Cyp 200 mg/week only, no arimidex, no HCG. How long did it take for your IGF-1 to increase after starting the DHEA...
  27. M

    Liver Detox Protocol

    This link is broken. Do you have another? Thanks! Mark
  28. M

    Hct coming down

    55 is still high. Also, you may feel good now, but with more time as your T level drops further, you may not feel good because of low T symptoms. 3.5 weeks you're at 1/3 or 1/4th of your peak which still might be 400-500. What a tradeoff brother... I was high 40's before TRT and try to keep...
  29. M

    How to Increase Good Cholesterol (HDL)

    When I took that, it pushed my liver enzymes (ALT/AST) much higher, so something to keep an eye on..
  30. M

    Testosterone too high after 8 weeks on 200 mg Cypionate / Week!

    I'm not sure I have heard of any examples where a 20% drop in T dose has cured elevatedHGB/HCT or E2 that is about double what people seem to consider ideal. An experienced doc (i.e. someone like Dr. Saya) would be able to advise whether a dose drop is worth trying. If the OP's doc is not at...
  31. M

    B12 with trt

    Are you using Labcorp Serum B12 or a specialty test from somewhere? What is a good level?
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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