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  1. G

    Just had 1st CT Angiogram Scan done. Anyone experienced care to comment in simple layman terms?

    I'm sorry if you've already mentioned any of the following, but K2, potassium, Vitamin C and low dose aspirin seem like good additions. Moderating stress is also key. Something to raise or prolong nitric oxide is likely a good idea. Sunshine when you can get it has many benefits. If y9our lp(a)...
  2. G

    Should I continue trt or not?

    The decision tree here leads to one thing under all outcomes and that is to get on an anti-cancer protocol. That means things like keeping insulin and blood sugar low, no seed oils, HIIT activity, eliminate visceral fat, periodic fasting, anti-cancer supplements like curcumin, etc. Dr. Nasha...
  3. G

    REALLY Struggling With Weight Loss: What Labs to Run?

    I agree with this, but with the caveat that you don't want to put yourself into a state of overtraining. I would slightly cut back on something else and, to start, add one BRIEF workout per week of either sled-pushing or sprints on a slightly uphill slope. Total workout time should be no more...
  4. G

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    Note that some compounds that increase "muscle size" are basically adding a lot of water retention (e.g. dianabol). There is a mechanism involving calcium IIRC that increases muscle contractile force without increasing the size or number of muscle cells. This used to be the goal of many anabolic...
  5. G

    REALLY Struggling With Weight Loss: What Labs to Run?

    My first thought was cortisol, but it looks like you've tested that. You might want to check your insulin levels and make sure fasting insulin is under 6 or so. You might also want to work with a holistic doc and test for chronic infections like mold exposure. I know people who have had very...
  6. G

    Long Term Clomid use experience

    Also, you might check out the book Adrenal Dominance which talks a lot about anxiety IIRC. I believe the author recommends a low dose of progesterone. Progesterone can be problematic in its own right for some men, however it may be worth looking into to combat anxiety.
  7. G

    Long Term Clomid use experience

    Two things...you might try some Lithium and see if that helps with your anxiety. Dr. Sandra Kaufmann thinks IIRC that 20-30mg per day is a reasonable dose, but you would obviously want to start low and adjust up to that only if needed. Also, when I was on clomid only, I could only tolerate a...
  8. G

    Has Anyone Tried Rad-140?

    The problem with this and similar compounds is they tend to be very temporary. There are fairly few things with enough of an experience base to be run fairly long-term even at lowish doses. Nandrolone is one for those who tolerate it. For RAD, LGD etc. there is a temporary boost, but for what...
  9. G

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    In addition, Oxandrolone is one of the few anabolics to be considered Female-friendly, so it is unlikely to have the effect you're looking for, although it seems like there are exceptions to everything so it is worth a try, but if it helps you, I would not think it is because it is related to DHT.
  10. G

    Nandrolone (Deca) Base TRT Trial

    It's not clear why you would change anything if you are in a good place overall. 400mg per week is a hefty dose already.
  11. G

    What are typical nandrolone plus TRT protocols?

    People dealing with mood issues may want to try supplementing lithium, at least until the N is out of your system. Lithium has other benefits as well.
  12. G

    Potential beneficial impacts of tadalafil on CVD

    Good to see a discussion of a very potent promoter of CV health with no mention of cholesterol. Nitric Oxide is a big deal. Also, as Dr Kendrick discusses in his book on heart health (The Clot Thickens), statins (weakly) promote Nitric oxide, so their barely detectable benefit may be due to that...
  13. G

    What are typical nandrolone plus TRT protocols?

    The times I've tried ND I seemed to get a very subtle version of what USMC describes, however NPP doesn't seem to have any mood negatives.
  14. G

    PT 141 not being made by Empower!

    While not a compounding pharmacy, I have used Peptide Sciences with excellent results. PT-141 and MT-2 (which acts similarly, but with excessive (IMO) tanning affect) seem to be two of the most reliably legit compounds.
  15. G

    Kidney Concerns

    I've had some kidney concerns and in general I view the kidneys as a very under-appreciated risk. A few thoughts: - Get a cystatin C test. From everything I've researched, it is one of the best, if not the best, overall test of kidney function. Many of the other tests are very subject to...
  16. G

    Lower back pain

    I've had lower back issues off and on all my life and one of the first things to try is to lie on you back with a rolled up towel under your lower back (similar to a device called a lumbar extender). Even if this doesn't help, it is simple to try and if you feel muscles relaxing when you do...
  17. G

    CJC-1295 vs Ipamorelin vs Tesamorelin vs hGH

    I have tried all of these except HGH to try to resolve some nagging joint issues. My next step will likely be HGH and another con I would add is the apparent variation between different HGH sources. All the other things on the list can be tried at fairly low cost from reliable sources, however...
  18. G

    Growing Role of Lp(a) in Cardiovascular Risk Assessment

    Unfortunately, none of the studies I have seen assessing the risk of Lp(a) have assessed people with high levels who have truly heart-healthy practices such as low fasting insulin, healthy nitric oxide levels, avoidance of seed oils, low inflammation, sensible sun exposure, heart-healthy...
  19. G

    Excess niacin causes blood vessel inflammation and cardiovascular disease

    AFAIK, niacin is one of the few things that lower Lp(a). It is important to take a methyl donor with it however.
  20. G

    My CAC calcium score is high- Should I take vitamin K?

    While Vitamin K2 is a must IMO, (I use both forms) there are lots of other things to take as well such as Vitamin C. Read the book The Clot Thickens by Dr. Malcolm Kendrick. There are also things to avoid such as long-term use of Ibuprofen or Naproxen. Things which promote Nitric Oxide are also...
  21. G

    Test enanthate dosage??

    First, it's going to take a few weeks for your natural production to cease, so you will be in a a state of high fluctuation until you reach a new steady state. 160 per week still sounds very high to me. Some people do very well on a dosage like that but others do best on much lower dosages like...
  22. G

    Leaky gut

    DR. Gundry's book Gut Check covers this topic I believe. I haven't read it but I have heard him interviewed on the topic. Curing his own leaky gut apparently resolved his enlarged prostate. There is a test for it (Zonulin and/or LPS maybe?) but I have forgotten exactly what it is. The cure...
  23. G

    Tirzepatide vs Semaglutide: Pros and Cons

    This has puzzled me too since (among other things) these drugs apparently slow down intestinal motility, however I understood slow food passage to be associated with (and likely causative of) colon cancer.
  24. G

    Time to lean bulk?

    IMO, you should absolutely be training to gain muscle and for all-around athleticism. Low muscle mass is not good, and you don't know whether the other aspects of your protocol are sustainable until you have the workload you need to maintain long-term. 8% is somewhat arbitrary and likely not...
  25. G

    DSIP Spray

    I have not used it but have heard that it takes many hours for it to have an effect, so taking it in the morning often works better, but you will have to experiment and see.
  26. G

    I'm in my early 40s and my calcium score came back 200 with most of it in the LAD. How did this happen?

    Kudos to you for actually reading and educating yourself. That book essentially becomes a tool against which almost all actions can be validated against. It's also worth noting that statins are well-known to not reduce plaque and apparently hasten the calcification of soft plaques, which the...
  27. G

    I'm in my early 40s and my calcium score came back 200 with most of it in the LAD. How did this happen?

    Two additional thoughts... Dr. Gundry mentioned in one of his books/podcasts that there are actually long-lived, healthy people who smoke, however they also live in areas where their diet is very high in Vitamin C. The mechanism is apparently that smoking causes very high oxidative stress which...
  28. G

    I'm in my early 40s and my calcium score came back 200 with most of it in the LAD. How did this happen?

    I agree that 500mg of androgens per week is likely a net negative (although how much an active lifestyle counters this is worthy of discussion.) However, singling out that one thing does not seem valid in comparison to other potential contributors. Further, it's not really relevant now and could...
  29. G

    I'm in my early 40s and my calcium score came back 200 with most of it in the LAD. How did this happen?

    Then read the book!!!! There is no substitute for becoming literate on the details. CVD is a combination of 1) damage to the glycocalyx and endothelium, 2) excess blood clotting to repair the damage, and 3) inadequate removal/reabsorption of the repair (plaques). If lowering LDL reduced these...
  30. G

    I'm in my early 40s and my calcium score came back 200 with most of it in the LAD. How did this happen?

    I would strongly suggest reading the book "The Clot Thickens" by Dr. Malcolm Kendrick. I'm going to post a formal book review here before too long but after reading it you will be vastly more fluent in the process of heart disease, (and LDL is a very minor player.) From what you've said, smoking...
  31. G

    My PT141 Arrived Today - Is 20 Units Considered Too Much?

    If you know the amount of liquid in the vial and the total mg of PT-141 then you can calculate it. So for example, if the vial has 10mg of PT-141 and you added 5 ml of water, then that would be 2mg for a full syringe, so 1/10 of a syringe would be 200 MCG.
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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