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  1. R

    Low SHBG and Free Estrogen Impacts?

    Yes I know..yet another low SHBG post. I have been googling and searching this forum and can't find anyone referencing lowish SHBG and the relationship to free estrogen. My Dr. says I am a hyper-metabolizer, hyper-excretor and hyper-converter to estrogen. Seems like a bad trifecta! My Pre-T...
  2. R

    Trimix Antidote-Treatment for Priaprism: PHENYLEPHRINE HCL INJECTION

    Has anyone self administered with Phelylephrine as mentioned here? I haven't found any threads where someone says that they have. The question I have is needle size - I am hoping that I could use my 30 gauge 1ml insulin syringe to inject into my erect penis with 1ml every 5 mins? 120mg of...
  3. R

    Anyone inject Phenylephrine HCL for priapism?

    Sorry, I should've clarified that the main thing I am interested in is what size needles to use. I have found medical information that says Des will use an 18-20 guage needle but I was sure hoping I could use a smaller needle if possible.
  4. R

    Anyone inject Phenylephrine HCL for priapism?

    Hi All - Has anyone injected Phenylephrine as referenced in Nelson's post ? I have some arriving on Friday from Empower and want to know dosage and needle size that anyone would recommend. I am hoping to not need it but if I do I am hoping that I can use my same 30 gauge insulin pins that I use...
  5. R

    TRIMIX Dosage Forum

    4 tablets (120mg) of real Sudafed from behind the pharmacy counter, running, squatting, cold and hot showers, gripping it...You name it!
  6. R

    TRIMIX Dosage Forum

    I feel the need to update again for any other hyper-responder out there that stumbles across this thread. I attempted 3 units last Tuesday night and ended up with a 7 hour erection. So I guess my margin for error is 0 and there is no rhyme or reason why some days it is a nice erection lasting...
  7. R

    TRIMIX Dosage Forum

    Thank you Dr. Saya, I may have to explore those other medications if my low dose experiment fails. Another update: On Friday night I attempted 4 units and had a 6ish hour erection. On Sunday, I tried just over 3 units with great success at around 1.5 hours. I will try 3 on the dot next time. I...
  8. R

    Anyone using .5cc syringes for injecting Trimix?

    Yes, I bought .3cc syringes for this purpose as I am only using 5 units or less. This syringe size makes it much easier to draw the small dose.
  9. R

    How to promote 5AR and DHT conversion

    Vince - What is your dosage/frequency for the cream? I was recently prescribed 1 click of 50mg/ml (.25ml) cream applied to my scrotum once every day day and my DHT shot up from 680 pg/ml to 1370 pg/ml on a 112-955 pg/ml range in just only 2 weeks! I have since stopped (had bad acne and I think...
  10. R

    TRIMIX Dosage Forum

    Another update: On Tuesday night I attempted 4 units and had very little to no success. Last night I attempted 5 units and ended up with a 6.5 hour erection again unfortunately (not rock hard this entire time but was erect). The injection site was the same as my successful 5 unit experience...
  11. R

    TRIMIX Dosage Forum

    Quick update: On Saturday night I used 5 units again BUT used a 5/16" needle and had a great erection for roughly 2 hours. I am going to try 4.5 units tonight. I am really thinking I over shot the sweet spot a few times with a 1/2" needle. Time will tell.
  12. R

    TRIMIX Dosage Forum

    Nelson, here is a pic of 5 units with a .3ml insulin syringe.
  13. R

    TRIMIX Dosage Forum

    Hi Nelson - I am using a .5ml syringe with 30G and 1/2" insulin needle (same as I use EOD for TRT). I will post a picture soon but I only fill it up a few "ticks" as they say to single digit units (under the first .1ml marker) which leaves most of the syringe not utilized. It almost looks...
  14. R

    TRIMIX Dosage Forum

    I wonder why 5/16" needles wouldn't be the standard recommendation? It seems that there would be less margin of error of being too shallow vs too deep. Thoughts?
  15. R

    TRIMIX Dosage Forum

    I'll try again with a 5 unit dose but not 6 as that was apparently far too much for me.
  16. R

    TRIMIX Dosage Forum

    I thought about that but I guess I'll never know. I've tried the same way each time. About an inch up from the base at around 2:30 dodging any obvious veins and 1/2" fully pressed in. I'm wondering if I should try Bi-Mix which might be more forgiving for me? Not sure.
  17. R

    TRIMIX Dosage Forum

    So I've tried Trimix 5 times with varied results. This is the standard 30-10-1 mix from Empower. Attempt 1: 5 units (.05ml) decent erection lasting around a half hour. Attempt 2: 8 units (.08ml) resulting in an ER trip and an erection around 8 hours. 120mg Sudafed did nothing. Urologist in ER...
  18. R

    4 Months In - No Improvements - Major E2 Issues - Switching to Defy

    Sorry, realized I didn't answer your other question. I really don't feel much different from Pre-TRT which is frustrating. Each change of protocol hasn't really brought any changes for me that are noticeable. I will say that I think I am having more nocturnal erections. My libido comes and goes...
  19. R

    4 Months In - No Improvements - Major E2 Issues - Switching to Defy

    I wasn't happy with the response time of my Doctor. I requested this E2 draw on my own and this was 2 weeks after EOD injections. The next draw was on that same protocol and when he stared me on .25mg AI EOD.
  20. R

    4 Months In - No Improvements - Major E2 Issues - Switching to Defy

    I am 4 months in with TRT and have yet to feel/experience any benefits. Please, please look at these labs and let me know your thoughts. And let me know if you have any questions. I am moving to Defy and have my first consult with Dr. Saya in early January. My doctor now is recommending I...
  21. R

    Struggling EOD Protocol - Low TRT Levels?

    Are you saying that an EOD protocol will drop SHBG or that TRT continues to drop SHBG and mine might still be falling and therefore metabolizing the Testosterone quicker?
  22. R

    Struggling EOD Protocol - Low TRT Levels?

    Ok, I edited my post with injection times. The first was 48 hours after injection as well.
  23. R

    Struggling EOD Protocol - Low TRT Levels?

    No worries, sorry for the confusion. The first draw was 9/21 and was 6 weeks into my first protocol (E3.5D). Unfortunately, I haven't felt much different in the 9 weeks which has been very frustrating. I would say that I have better morning erections, still not great. Energy, brain fog, and...
  24. R

    Struggling EOD Protocol - Low TRT Levels?

    Actually I take that back. The second draw was 48 hours after as well, it was my absolute trough on an EOD protocol. Yes, the 10/21 draw was 2 weeks into AI. I edited my original post.
  25. R

    Struggling EOD Protocol - Low TRT Levels?

    The first draw was 48 hours after injection on my 70 mg E3.5D protocol which was a total T of 766. The Total T of 519 was 4 weeks in 40mg EOD protocol and was 48 hours after injection.
  26. R

    Struggling EOD Protocol - Low TRT Levels?

    To clarify my current protocol: 40mg Test-C EOD .25 Adex EOD on injection day 350IU HCG E3.5D
  27. R

    Struggling EOD Protocol - Low TRT Levels?

    I have been struggling to get better and am on week 9 of TRT. I started with 70mg E3.5D and 200IU HCG EOD for 6 weeks and ran into major E2 spikes. I am currently looking into switching to Dr. Saya at Defy as I am hoping to dial into something that works. Please see my progression below, I am...
  28. R

    Introduce an AI or Dosage Adjustment?

    **Update** Still experiencing ED and low libido. I am now experiencing some serious night sweats after starting the AI (maybe every other night). With my high E2, I am going dose at what I was prescribed at .25 EOD and if I feel that I am getting low, I can back off but I need more releif and...
  29. R

    Introduce an AI or Dosage Adjustment?

    The blood draw was on an off day of my EOD injections. 24 hours after my injection.
  30. R

    Introduce an AI or Dosage Adjustment?

    My recent conversation with him was to tell him I switched to EOD imjections before meeting with him because my E2 was 63 and I was getting sides. I will not meet with him now for another month of using Anastrozole. I may need a new doctor with an E2 this high.
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