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Hey LakeGuy81, you hijacked my thread! No worries, seriously. But still might be better to create your own thread to track your progress. I don't think Testosterone will effect resting heart rate. 2.65 TSH could be sub-clinical hypothyroid. I don't know about hashimotos and the antibodies...

I'm almost 50 now and have been training - running, weight lifting for 25 years. I'm fit, probably 12% BF. I don't run long distances. I do a 20 minute trail run once per week and a few hill sprints at max effort on another day. I remember when I was in my 30s that my resting pulse would be in...

My HCT/Hemoglobin has varied much more than that just based on the day, how hydrated I am. I don't think you can ascribe the change to B12 levels... at least not without more data points.

I got hot flashes when my E2 was low. As others said, spend the $50 and get tested :-)

Skimmed the thread. Elevated H/H makes me irritable/anxious. The nurses pulling my blood told me it's common for people to feel relaxed after getting the blood pulled. You can get a double-red procedure where two pints are removed, centrifuged in a machine, then plasma and saline are added back...

I know this it a little OT, but am curious on your IGF-1 before and after arginine/citrulline? Also how much of these aminos you are taking?

I read it's better to use surface area when estimating a dose across species. A simple practice guide for dose conversion between animals and human ResearchGate

I had a friend commit suicide in 2017 and feel/have thought the same way. I think if he had called me or I had called him how that day may have turned out differently. I empathize with you. It seems like we focus a lot on our physical health - muscle, BF%, lipid numbers, longevity, etc. It...

Make sure you are hydrated (and hydrated consistently) when getting tested. These values are sensitive to dehydration.

I think the Rouzier stuff has been taken somewhat out of context. The video is very long and I listened to about the second half of it. He has lots of studies which is appreciated. In what I listened to, the main points were: Studies showing disease correlated with high E2 levels were showing...

I feel good on 0.1 mg EOD. I take 100 mg on Sunday and Wednesday = 200 mg/week I have tested E2 sensitive many times and adjusted based on those tests. Mark

Vince, thanks, that was successful. The tablet dissolved nicely. I was able to get the tablet into a 1ml syringe and a total volume of 1ml including the Vodka and the tablet. I dispensed my 0.1mg dose and thought all was good. Today I look at the syringe and the tablet stuff (anatrazole and...

I take a tiny amount of anastrazole -- about 0.1mg EOD. I have been cutting up the pills and measuring with a scale. My scale has become flaky and I'm thinking it would be more accurate to dissolve 1mg in 1ml of water and take it that way instead. Yes, I know I could get it compounded into...

This would be a subject for another thread. Biweekly dosing is going to have a big roller coaster for both T and E. A smaller dose more often seems to be the current thinking...

Hi, I try to take in all of the data and make my own decisions. I've been thinking about adding a GH peptide and know about the benefits, but I have read that higher IGF-1 is cancer promoting, that we should strive for a lower IGF-1. I remember this being promoted by proponents of...

This reddit is "banned." Is there a new link or better info?

I have had hair get more curly. I'd prefer for it not to be. If you find a solution that doesn't involve side-effects, please let me know :-)

KevinC - I got hot flashes when my E2 was too low...

I read that thyroid meds can increase SHBG. Questions: 1. I have not found definitive info if it is the T4 in the meds or the T3 or both that cause this effect? 2. Is there any info on dose-response of Thryoid on SHBG? I'm being treated for hypogonadism (Cypionate 200mg/weekly +...

Dr. Saya, if you had a list of supplements that you see elevating liver enzymes, it would be a useful thing to post. Thanks you, Mark

Some people can't donate for various reasons. The therapeutic phlebotomy is really the same as donating except the blood is discarded. There is also a "double-red" therapeutic procedure which uses a special machine to remove a pint of blood, centrifuges it and returns the plasma to you, then...

I might be misunderstanding, but... It would be nice if there wasn't a minimum 52 HCT, other than perhaps a minimum for safety. My reasoning is that if you're trying to maintain your HCT in a narrow band, say 45-48, you'd want to get a therapeutic when you're at 48-ish. Yes, doing it at 52...

IMO - I think it would be better to try to fix someone with a TT of 600 without replacement first. Parts of your system are working OK. Maybe dealing with lifestyle and/or thyroid would fix SHGB and even bring up TT a little more. Replacement is a long-term commitment and requires some...

Here is another study on NAFLD and dietary interventions using Serine and others. http://msb.embopress.org/content/13/3/916

Gene, My DHEA-S is bottom of range and my IGF-1 is 110. I ordered up some Fountain of Life Micron5 DHEA Ultra Micronized DHEA 25 mg 180 sr tablets made by McPherson. I'm on T-Cyp 200 mg/week only, no arimidex, no HCG. How long did it take for your IGF-1 to increase after starting the DHEA...

This link is broken. Do you have another? Thanks! Mark

55 is still high. Also, you may feel good now, but with more time as your T level drops further, you may not feel good because of low T symptoms. 3.5 weeks you're at 1/3 or 1/4th of your peak which still might be 400-500. What a tradeoff brother... I was high 40's before TRT and try to keep...

When I took that, it pushed my liver enzymes (ALT/AST) much higher, so something to keep an eye on..

I'm not sure I have heard of any examples where a 20% drop in T dose has cured elevatedHGB/HCT or E2 that is about double what people seem to consider ideal. An experienced doc (i.e. someone like Dr. Saya) would be able to advise whether a dose drop is worth trying. If the OP's doc is not at...

Are you using Labcorp Serum B12 or a specialty test from somewhere? What is a good level?

Cool, keep us in the loop. WRT - Potassium (or Sodium). It's the Bicarbonate that's key to alkalinizing...