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This is a really good post. I also think the HCG messes with my E2 levels and causes some major moodiness. That said, I think it does help to some degree with libido...and hurts it as well. I am one who worries about cosmetics so having full nuggets matters to me. That said, I am considering...

Well said.

Did you figure out a way to lose the weight and belly fat? I am struggling with the same issue even though I eat well and exercise.

Are you still taking this Nelson. Is it something I could ask my cardiologist for?

Respectfully... switch to shots... I messed around with every type of cream/gel known to mankind. In my experience it was just impossible to dial in consistent levels.

Vince as you no doubt know Rand McClain in his videos is shooting for E2 of 15-20 (sensitive test). I just got my results back and E2 was 20. Feel pretty good... not great, but good. I acknowledge that much of this comes down to how one feels, however what in your view is an optimum E2 level?

Thanks Vince

Thanks for your patronizing response...get a life

I didn't answer the water retention issue...

OK went to daily injections with no HCG. Injecting 10mg/ml a day for a total dose of 140 mg/ml a week. Just got my labs back and they are pretty damn perfect, i.e, total T = 1039; free T = 19.7 (7.2-24); DHEA = 256.1; Estradiol = 20.4 (8-35); SHBG = 31.1 (19.3-76.4). Pretty damn perfect...

I feel like it spikes my E2, but I also think it helps with libido.

In the past two weeks I probably added 10 pounds of water weight. I am working on how to sequence HCG shots with my 100mg of Test C per week. I think HCG spikes my E2 given the amount of water weight I put on. I took .5 mg of Arimidex and I think I dropped 7 pounds of water weight in 36...

CW that is really helpful information. Thank you. Did you ever consider moving to daily injections of HCG for the same reason...that is to ensure more stable levels and avoid spiking E2? My intuition is telling me that my E2 levels are being bounced around more by my HCG injections then by my...

What is the best way to dose it without spiking E2?

My full regimen is below: Test Cypionate 28mg every day (was 56mg EOD before) HCG 125 IU daily Anastrozole 0.08mg daily Desiccated Thyroid 1 grain per day Tadalafil: 5mg 2x per day L-Arginine 3000mg 2-3x per day L-Citrulline 1500mg 2-3x per day Pine bark extract 150mg 2-3x per day Vitamin D3...

I did read it. What is your preferred dosing schedule Test Cyp and HCG?

So who is right? Does an AI work with elevated E2 via HCG or not? If so, no wonder it is so difficult to get E2 dialed in.

Fair enough Nelson. I am reluctant to introduce something more that impacts blood pressure since I am already using Cialis. I am also in agreement that Arimidex is a tricky drug. What I do notice is the HCG is what seems to kick of symptoms like nipple and check skin sensitivity. This is a...

So let me get this straight...If E2 is being driven more by the HCG than the test Cyp, the AI is useless? What do people on HCG monotherapy do to deal with elevated E2?

I don't want to say forget Arimidex, but as has been said repeatedly on this site, be cautious, start at a very low dose and do your blood work.

All right Vince you were 100% right...E2 crashed... Lesson learned. Woke up last night with muscle and joint pain so bad I thought I had the flu. Fortunately I had only been taking Arimidex for a few weeks and I hope my E2 will rebound. In my case, I started to feel better once my E2 started...

Seriously I appreciate the thoughtful and measured feedback.

That is so funny.

Lighten up Francis. That said, I also want to acknowledge that the HRT community has a tendency towards a "more is better" approach to almost everything and Arimidex can be highly dangerous for those folks.

62 on a ultrasensitive Kaiser test when normal is <29

On my ultrasensitive test from Kaiser several weeks ago my E2 was 62 when according to their test I should be sub 29. I tend to convert. I have stopped the Arimidex, but I am grateful I have it on hand. Over the years I have definitely dealt with high E2 symptoms and I feel like most of the...

Got my blood work back and wanted some input. Currently on Test C 100 mg/ml a week taken every third day with 250 iu HCG. I have been taking Arimidex .5 mg EOD. Got my blood work back. Timing as follows: Tuesday Took&#8203; 50ml Test C 250 iu HCG .5 Adex Thursday .5 Adex 5 am Blood draw...

The only thing worse for your endocrine system than methadone is Suboxone. Suboxone is fine if used for a few weeks to get clean. Maintenance Suboxone is to be avoided like the plague. I took it for six months and getting off it was a nightmare. For a variety of reasons I was unwilling to do...

23iu of HCG? Is that a typo?