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My SHBG fluctuations between 8 and 11. It’s interesting you say that, I have considered the idea that my “free” e2 is the problem. How does one test for free E2?

Libido issues mainly - Unable to feel dialled in after many years of trying.

Does anyone have any experience with using a SERM to increase SHBG. I am low single digit and am unable to impact it with frequency changes etc. I have read that a SERM like Roloxaphine / Clomid / Nolvadex may be effective. Does anyone have any experience with this as an effective way to treat...

I have always struggled with libido and generally feeling good on TRT. I am a relatively low aromitiser and have single digit SHBG. I have tried just about every protocol under the sun over the last 10 years. Over the last year I have been experimenting with lower doses (60-90 mg per week)...

I have the exact same problem - The only relief I seem to get is when I run my test higher (210+mg / week), that being said I very rarely have any libido. Low SHBG and troubles dialing in TRT seems to be a common issue. The closest I got to any improvement libido wise was very recently, my test...

Good health otherwise. Body fat 20% ish. Fasting insulin and blood pressure all ok.

I’ve got single digits SHBG, which is why I use daily dosing. TBH it didn’t make much of a difference but I’ve never gone back to any other dose. I have just started P5P to see if that makes a difference. Thats useful to know regarding progesterone. My DHEA is in range so I’ve never added it...

Do you care to elaborate on why the lab work is not a cause for concern? High prolactin and high progesterone nothing to worry about? I’ve been on TRT for years now and never really felt dialled in. I inject 140mg split into daily injections. I’m a relatively low aromitiser - when I go to...

Zero libido - Poor EQ Is there any what to lower progesterone how much of a problem is high progesterone? My prolactin, whilst elevated is this a value I should be concerned about? 140mg test E pinned daily. (I have single digit SHBG since I started TRT.

Oh I was just curious - It had been suggested that having higher than normal androgens could be a contributing factor to a suppressed SHBG. Your post has been extremely helpful. I’ll be lowering my dose to get my free T in range like you suggested and see what happens. Thanks again

that’s incredibly helpful - I’ve been on TRT for 8 years and have had libido issues the whole time. I am a low aromatiser so my E2 has always been low so I’ve been hesitant to give the lower dosages a try but you have convinced me. Out of curiosity, you said it fixed your low SHBG - Did you...

Thanks for your reply - Would you say the lower dose had a significant impact on your Libido? What is your dosing schedule like - twice per week or more frequently? Lowering my dose is my next plan of attack.

Thanks for taking the time to respond - I fully appreciate the idea of the “normal range” having little to nothing to do with a man’s well being but it’s fair to say that it could be an indicator or a guideline to some degree. As an example of a guy has everything else “appearing to be healthy”...

Does anyone understand the implications of having a very high level of androgens despite being on a moderate dose of TRT. I’ve struggled for years to get “dialled” in. Mostly libido / ED I’m not one for chasing numbers per say but given all the variables, getting things into range is at least...

I am not at all worried about lowering my dosage - IMO the less I need to use the better. I do have aromatise issues as well which has held me back from lowering it, that being said I have just started estrogen therapy which should mitigate any low E2 issues. I’ll probably run that for another...

It’s interesting you say that - My free test is very high, due to low SHBG probably but my free androgen index is 325.8 (range 35-92) Do you think there is value in trying to get the androgens within the normal range? This would mean massively lowering my trt dose (currently on 120mg / week)...

I’m definitely not overweight

Has anyone managed to successfully raise SHBG. My SHBG is crazy low - Way below the reference range to the point sometimes is doesn’t even register. I’ve tried changing injection frequency and it’s made zero difference. Has anyone managed to successfully raise it? I’ve always struggled with...

I have the same issue - it’s really hard to finish. If I was a teenager I’d love this problem but as an adult, lasting for ages is more hassle than it’s worth :)

How is your libido?

I mean my goal is improved libido - Whether I use a lower dose or not.

I have battled with libido for years and it has been suggested that my E2 is too low and I am probably running my test too high. Despite only running 140mg my Free test was sky high, very high androgen index and low SHBG. So in order to attempt a more favorable test/androgen to E2 Ratio I...

So I upped my HCG and lowered my test to try to achieve a more favorable Test to E2 Ratio. I have heard a lot of guys having a better libido on a lower dose. The results are surprising. My test went from 140mg down to 87.5mg and increased my HCG to 500iu EOD. This is my results after 4 weeks...

Pretty compelling stuff

Question for the low E2 guys. Does anyone add E2 exogenously alongside their TRT. If so, where did they start dosage wise and how successful was it. I’ve never had any libido on TRT - My E2 is always on the lower end and my SHBG is extremely low. Aside from the shot libido, I don’t feel that...

Prolactin would be the only one I couldn’t eliminate from the list.

I’ll absolutely try the prolactin route I do have ADHD - Fully diagnosed

i do feel I am a little less sharp sometimes, cognitively speaking.

Nah everything else is in check - I’m in great cond I mean libido is the main one - I have noticed my ADHD has got worse and general sense of well being isn’t ideal but I think that’s down to the libido tbh.

I ended up crashing my test levels by not eating a single carb for over a year and doing insane amounts of cardio - I was young and stupid and didn’t realise the toll I was taking on my body. After a year of no energy, depression, lethargy snd brain fog I went to the doctor who told me my test...

Yeh I have considered prolactin may be the issue but I suspect it’s more likely my free test to E2 ratio. I aromatise at such a low rate - Even on a gram of testosterone my E2 has still been within normal range. There’s just so many factors that are intertwined it’s hard to know where to start...