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I had a Kidney Stone a few months back, the pain was shooting into my left testicle. Never felt pain like this in my life! Went to the ER, the Dr orders a Ultrasound of the testies, looking for testicular torsion. Ultrasound shows no torsion, but there is a small lump on the epididymis. Lucky...

My original T level was @ 101. Dr put me on 200mg every 2 weeks for the first 3 injections, then 200mg every 4 weeks after the 3rd injection. Of course I wanted to know more so I hit up Google, found Excel and learned my Dr was not up to date with TRT. Lucky I was able to get my refills and...

So I should be fine trying the daily injections is what I gather here. If I do attempt to switch, I will leave HCG the same, 350Ui 3 times a week. My main questioning, should I stop the AI instantly, and then add back if needed? I tried to go with a 3 times a week T injection schedule once, I...

Sensitive estradiol hovers around 35. 40 is a bit high, below 30 is too low for me, I think it is due to my higher trough level, but I'm not sure.

My SHBG is 26.9 with a range of16.5 - 55.9 nmol/L T level is 1030 @ trough with range of348 - 1197 ng/dl Free T is 24.5 and a range of 6.8 - 21.5 pg/ml My T levels are a little high, and I seem to be retaining more water than I would like. Will be doing labs again this coming Wednesday, will...

How did you guys calculate what a daily dose would be? I am using 70mg twice per week, and am taking AI three times per week. Reading this I may be able to get rid of the AI by doing daily injections. Thanks.

when I take too much anastrozole and E2 gets rather low, I experience the same thing. Erection will be rock solid, it will feel as if I will reach orgasm at any moment but it never comes (pardon the pun).

Pretty sure this is a non issue with those on TRT. We are providing exogenous testosterone and suppressing the "natural" Production of T.

Thanks for the link, I found a article related to CYP3A5 but have no idea what it means. It is a little over my head.

I tried to read this, but got lost fairly quick! My DNA says I am a CYP3A5 non-expressor can someone please explain what that means in accordance to the article? I seen the article speak of CYP3A4 quite a bit, but not a whole lot about CYP3A5. Thank You

I recently had my DNA processed by Ancestry. The whole looking at where you come from is pretty interesting to me. Anyway, one is also able to submit their RAW DNA to servers who crunch the DATA and look for Genetic Defects. I found out I am a CYP3A5 non-expressor. This is some sort of enzyme...

The size of this stain is about the size of a Pop Warner sized Football. The spot is also directly in-line with my injection site, at the shoulder. I inject fairly early in the morning, and normally do not lay back down until after dinner (bed time). I've been known to sneak in a nap, but that...

I have this "spot" on my sheets, it is up close to my pillow. Picture a football, only not as oval, and it appears to be a oily stain. This spot has had stain remover applied to it, washed in washer over and over, it just wont come out. For the life of my I could not figure out what it was...

I know the feeling, I'll get this way with both low and high E2. The coffee sends me right into anxiety land. If it were a meme the title would read "That Escalated Quickly" lol.

Thanks. Anastrozole has been a part of protocol since moving to Defy. My estradiol was in the lower 50's without it.

Just dropping a post to say "Hello" and Thanks for having such a awesome place for Mens Health! I am secondary, like most I am using Test CYP, and HCG. I also have to use a small amount of AI, also I am one of those who do better with a higher E2 35-40 as my trough levels are near 1000. Not...