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Splitting the 200 into 100 mg twice a week might be enough to lower e2 some since it's not that high. I'd do that and see how you feel in a few more weeks. So McClain is ur doctor?

Is Dr McClain ur doctor ? I thought he uses ai with everyone.

He has them applying it twice a day if I understand correctly. That's why they say high free t all day and night. I'm curious too his opinions on frequency and dosing if doing injections is the only option your Dr can provide us. I think I'm his practice though he has no one on injections...

Thanks again to both doctors for responding to each other as well as us. A few questions for you both. I'm wondering if maybe the reasons Dr. Nichols sees no one with estradiol issues and Dr. Saya does is maybe because the topical cream Dr. Nichols uses helps increase dht enough that it offsets...

This thread is very informative. Love hearing feedback from different doctors. Dr. Nichols is there a cutoff that you feel is too high of a dose or free t levels that are too high or do you just believe in increasing until all symptoms are gone? Also looking forward to hearing what you have to...

Very informative information Dr. Nichols. Glad to have you here! Are you saying running the normal free and total testosterone by labcorp isn't accurate enough for free t or isn't that a huge thing to worry about as long as the free testosterone levels are keep elevated?

I think I remember correctly Nelson saying once that teen males can have estradiol in the 70-80s. If he could post a link to that article it would be interesting to read.

Would love the hear more replies from Dr. Nichols very interesting information being stated.

Greatly appreciate that answer Dr Saya!

Dr. Saya I know you have said befere on here that you think 45-50 is the cutoff on the sensitive test where you above that feel it should be lowered. Do you still feel that way or if you had someone at 60 on sensitive test with no problems would you be ok with that long term. The confusion I...

Did you think his 1 mg of anastrozole for estradiol over 60 to be a bit high to start out. Varying frequency, dosage differences, and opinions on what levels to begin treating always are confusing considering every Dr has a totally different opinion and approach.

Great interview!!! One question is he saying that a ten to one ratio Is ideal for testosterone to estradiol? That seems really low?

I find this to be very very interesting! It would be cool to have Dr. Saya comment of this too. Is it possible that those of twice weekly anastrozole actually have lower estradiol levels at peak and not trough because the anastrozole is peaking then?? If so would this mean we might be better...

For those who can't tolerate high estradiol Vince Carter being one did you have brain fog or fatigue or what were the symptoms? Aside from the major gyno and ed curious what symptoms some of you feel?

I don't really see the need to worry about it. Looking back at your previous blood test your h and h is staying about the same and you seem to be doing well and you are on metformen so the little extra b12 I can't see to be hurtfing you. If it would have elevated your h and h then I'd worry as...

What is the laws pretaining to buying cialis online domestic delivery?

It says it can't be taken orally though which I believe isn't true. I've taken 1200 mg orally for years and it has worked.

https://liveto110.com/estrogen-dominance-syndrome/

Was just reading an article that said NAC can help regulate estradiol in women. Has anyone heard of this for guys on trt? Would 1800 mg be a safe dose?

Thanks great answers! So I'm gathering you don't really feel there is an estradiol level that is considered unsafe in men? I know some doctors say that past a certain point no matter how the patient feels high or slightly high estradiol is unsafe for the prostate and could increase clotting risk.

Thanks great answers! So I'm gathering you don't really feel there is an estradiol level that is considered unsafe in men? I know some doctors say that past a certain point no matter how the patient feels high or slightly high estradiol is unsafe for the prostate and could increase clotting risk.

Hi doctor. In response to ur reply about trough levels how often do you generally recommend patients inject? To have a patient above normal reference range on average how many milligrams weekly does that take? Lastly if the patient exhibits no systems do you believe in just letting the sensitive...

Hi doctor. In response to ur reply about trough levels how often do you generally recommend patients inject? To have a patient above normal reference range on average how many milligrams weekly does that take? Lastly if the patient exhibits no systems do you believe in just letting the sensitive...

Vince makes a good point NAC may be helpful for cholesterol. I did add that to my daily regimen also. I also think along the lines as Vince on ai if you are feeling good idk if it's worth tweaking.

Looks good except for hemoglobin and hematocrit. If they get much higher you need to donate blood. Drinking lots of water and daily cardio should help some in that area if you aren't already. Hdl is a bit low but mine used to be also when my total cholesterol was as low as urs. I added a few...

Are you on trt? If so what's ur protocol and how do you feel?

I said in my first post I tested at trough. Those are the basic ranges at labcorp. 8-35 range has been labcorps sensitive estradiol range for a least two years now.

Estradiol 38.3 range 7.6-42.6 Sensitive estradiol 31.4 range 8-35 Testosterone 1211 range 348-1197 Free testosterone 25.8 range9.3- 26.5 Vince I've tried .25 mg ai once a week instead of twice felt my erections weren't a solid might not have been related though. Never tried no ai.

I just had both the regular and the sensitive same exact draw. Sensitive was 31.4 and standard was 38. My energy and libido are not so hot. Do you you think getting my estradiol lower or higher would be a good direction to go? Currently injecting every 3.5 days and taking .25 mg anastrozole 24...

What is NDT?

You are on armour too correct Vince? I take it you have heard nature-throid is gaining steam too lol