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I do have a question for anyone: Does anyone backfill their syringes ahead of time? If so, how far out do you do it? Is there any danger in doing that? How do you best store the syringes for later injection? Any concerns about maintaining sterility? I ask partly because I'm going to be...

Thanks Vince! I will certainly keep checking in.

Thanks Vettester Chris, I do have some 31g insulin syringes, and can imagine it takes a little while to draw using that. Jay Campbell mentions the possibly of site infections using a needle that small for IM- is there any risk of that in your opinion, for either IM for SubQ? I am keen on...

Thanks Gene Devine! I certainly intend to experiment with different needles to find what works for me. When switching, do you do anything in particular to ensure you don't lose much/any of the medication? Do you do SubQ or IM? I did try to withdraw a little further to pull the oil from the...

Thanks MG123- do you have any recommendations? I'm using what Dr Saya recommended, though I'm happy to order on my own and try different gauges/needle lengths/types, etc. I would have before I started, but honestly I find the needle/syringe options so confusing and hard to decipher I thought it...

Hey guys, Just reporting in- after much deliberation I decided to take the plunge and begin TRT through Defy. I had my first injection today and despite a bit of an adrenaline rush when I injected, I think it went well. I'm doing Test Cypionate SubQ with a 25g 5/8" needle, 70mg 2x/week...

heyguise, Welcome! I am in a somewhat similar boat as you in that I'm 31 and leery of the long-term commitment and the unkown (and unknowable) potential complications. I've been monitoring my blood work for about 16 months with as yet mediocre results attempting to increase my T naturally...

Lucky Luke, That is very unfortunate that your physician seems to be mismanaging your care so cavalierly. I cannot speak to international TRT-prescribing doctors, but I have on previously mentioned Mike from Danger and Play in a thread about stopping TRT cold turkey. From another thread...

Dear Thomas, Welcome to ExcelMale! You might consider visiting the sidebar http://excelmale.com/HCG/ and filling in your information. There are some doctor who specialize in assessing a need for HCG and prescribing it for men who are being cared for by a different TRT-prescribing...

Wow- those prices seem great. Does anyone know if this would work for Defy patients, or do they require internal order fulfillment?

Hi Lars, Welcome to Excel Male! Congrats on having what sound like healthy fitness habits. May not be what you want to hear, but at 544 total T at 44 years old, I think many doctors would have a hard time justifying TRT as medically indicated. Even though they are on the low-ish range of...

Pacman- I think the main concern is that decades in, you may start to form scar tissue from the cumulative effect of the micro-trauma from injections. One recommendation I've seen from Jay at Fab Fit Over 40 is to use Foam Rollers or Beastie Balls to break up some of that scar tissue that...

Hey Trinity- physiologically it makes sense to me that smaller more frequent dosages of both T and HCG would be preferable. I think for Nelson the issue is compliance. Many guys just don't have the means or wherewithal to dose every day, even if it would more closely mimic natural patterns...

I wondered the same, and I've seen Jerry Brainum's video https://youtu.be/FBx-g0sQHL4, where he suggests that testosterone is best injected morning time, in the first hours after waking, when our body's T levels are typically peaking, and that our body responds to exogenous T during that window...

Hi Timothy, I can speak to your specific situation, but I know TRT patients, doctors and advocates generally advise against simply stopping, as your endogenous production will have been suppressed and you'll be operating near zero until your T levels re-normalize to your own baseline. That...

Hi Encore, Appreciate the comment. I'm not especially concerned about dis-incentivizing myself to continue with other self-care practices. I think of myself as a reasonably attentive guy who has approaches my own health seriously without being fanastical. It is possible that I am...

Indeed- welcome Paul. I've been learning as much as I can over the past 15 months and spend many hours poring through some of the threads here. Great information and great group of contributors. All the best to you in your study.

Dear Vince- apologies on the delayed reply. Thank you for sharing those links. I did look through them and read a bit more about primary vs secondary hypogonadism. Based on what I understand in my situation, my body is already doing as much as it can to produce more T, but the output from the...

Vitamin C, Thanks for the follow up here. I already do much of what you're describing. i would say that sleep and stress are my next major areas of lifestyle focus. Interesting that you mention dead-lifts specifically; that's definitely strongest of the major lifts. Haven't done 1RM testing...

Vitamin_C- thanks for your response, and it's great to hear from someone with a similar constellation of symptoms. Congrats on your T level improvements and gym gains. What sort of lifestyle modifications have you made that have brought you some success? And congrats too on your discipline...

Hey guys, Just ordered Nelson's book and have been reading through it, and just noticed the section on primary hypogonadism. Basically- it's when your testes just don't produce more T. The signal is there, LH and FSH tend to be high, but circulating T levels don't increase. Anyway- here's my...

Thanks Vince Carter- I have some speculations, but no clear sense of why my T is low. I do suspect, based on patterns going back to my youth, that my T has been habitually low for most of my life, though I have no blood work prior to last year to verify as much. I just know that I've long had...

Thanks Coastwatcher- as mentioned above, I think I will go forward with my appointment and discuss these concerns. If Defy docs are as open-minded and sensitive to individual needs and concerns as many members here report, I'm confident that they can advise me appropriately. And I do always...

Thanks xr88- I hope you're able to dial things in and find the improvements you're looking for.

Thanks ERO- good point about the importance of a skilled clinician. I know guys here have great things to say about Defy, so maybe it makes sense to just follow through and discuss these concerns with them. Sleep definitely seems to impact me heavily. I understand it can be a bit of a chicken...

Hey everyone, You can see my posting history to get a little more context of me. Short version: 31- Low T verified via bloodwork for the last 15 months- had some success naturally raising it, but it was transient. Am set to visit Defy soon. Over the last few days reading some of the struggle...

Can you help me understand the ranges Vince? The DHEA reference range is: 138.5 - 475.2 TSH reference range is: 0.450- 4.500 What numbers do you think are ideal/ what should I be aiming for? This is all foreign to me. Based only on the reference ranges, I appear to be in the normal range for...

Hi Vince Carter- is there a reason you think raising DHEA and/or TSH levels would be important?

Thanks Nelson- scanned through those threads. Very interesting: I wish there were a way to more easily understand and interpret those levels. They both appear to be right in the middle of reference ranges which is good I guess, but even those ranges are not widely agreed upon. Just goes to...

I agree Nelson. This is a field rife with misunderstandings and misinformation, and I am very grateful for the patience and understanding extended to me and others who are trying to learn the best, most factual information we can around testosterone and the male hormonal system.

Hey guys, Just got some new bloodwork in and will be visiting Defy in a few weeks here: Lipid Panel w/ Chol/HDL Ratio Cholesterol, Total 151 Triglycerides 40 HDL Cholesterol 76 VLDL Cholesterol Cal 8 LDL Cholesterol...