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Yes, but those drops are only temporary. After two weeks you’re back to 50% or more of your pre-donation hemoglobin level. Of course if you aggressively continue to donate for years the average hemoglobin declines long term. That was my experience donating while not on TRT. Guys on exogenous...

Did you check cortisol?

The edema and upper range estradiol may be related. As I said, I would get another E2, CBC, CMP, Iron Panel and RBC magnesium before committing to a lifetime of BP meds and diuretics.

Since you've been off TRT for 8 weeks, test E2 again. I'm suspicious of that. Also, make a list of everything you've taken - including supplements - since the blood pressure went up. As @JmarkH said, your electrolytes might be out of balance. I would go back and test E2 again, and do a CBC...

Which peptides did you use and in what dosages?

If you guys need an A+ platelet donation, just ask. I’ve got plenty for everyone. My phone is blown up with dozens of texts and voicemails from the local blood bank.

I didn't respond to your original post, but I think it's plausible that tetracyclines increase estrogen. Also, I seem remember reading somewhere that estradiol increases DHT... though maybe that's nonsense from the recesses of my mind.

What happens to you and others when the supply of enclomiphene runs out at compounding pharmacies? What then?

@Vince Did this unfortunate guy with sepsis provide any more details other than injecting "dirt"? I mean, did he not use an alcohol swab on the vial and injection site? Did he reuse a needle/syringe?

I believe he’s saying that low vitamin K2 was contributing to excessive urination, which in turn led to dehydration. The dehydration caused his hemoglobin to appear elevated. Speculation: the vitamin K2 (mk-4) he took reduced his dehydration, thus making hemoglobin appear lower on the test...

Vitamin K2 (mk-4 or mk-7)?

1. Topical finasteride (to limit systemic absorption) 2. Raise your progesterone level 3. Long shot - magnesium threonate supplements https://pubmed.ncbi.nlm.nih.gov/21034532/

Better safe than sorry.

What was your dose of progesterone cream?

I always use an alcohol swab and let it dry. It’s just peace of mind considering the cost of emergency care (in case of infection) these days unless you have platinum employer provided health insurance.

Can iron deficiency cause low aromatase levels? They fed mice a low iron diet (LFD) and then looked at various markers. The expression of CYP19A1 mRNA dropped significantly. CYP19A1 is part of the cytochrome P450 family and is responsible for making the aromatase enzyme...

Did you have any other symptoms during the months of heavy nighttime sweating that might be a clue to having an infection?

Tocotrienol supplements may help with inflammation if you don’t want prescription medication. Anti-inflammatory Activity of Tocotrienols in Age-related Pathologies: A SASPected Involvement of Cellular Senescence - Biological Procedures Online Fiisetin can also be used to target senescent...

Ever have vision problems on such a high dose of encclomiphene, such as eye floaters commonly reported by Clomid users?

I don’t intend to make a flippant comment, but how about the increase in gonadotropins in menopausal women? If elevated LH was causal instead of associated then every elderly woman should have Alzheimer’s Disease.

My father was in and out of the hospital (and ER) several times earlier this year, and none of the treating physicians thought his hemoglobin of 10 was a problem. And, of corse, they never did an iron panel on him. I eventually began giving him desiccated beef organ supplements (spleen...

The adrenals secrete weak androgens, glucocorticoids (mostly cortisol) and mineralocorticoids (aldosterone). Hydrocortisone probably has somewhat of a mineralocorticoid effect if taken at high doses. It’s mostly aldosterone that’s going to increase water retention by increasing the sodium to...

Whar is a mitochondrial test?

https://www.excelmale.com/forum/threads/clomid-clomiphene-citrate-treatment-may-take-up-to-9-months-to-show-max-sperm-response.25263/

Yes.

What are your current LH and FSH levels including reference ranges? Also, have your gonadotropin levels changed over this time frame, or have they remained stable?

Could be fatty liver. There is an inverse or negative association between NAFLD and SHBG.

I suggest you look into the effects of melatonin on adrenal function and cortisol secretion. https://pubmed.ncbi.nlm.nih.gov/29199635/

What are the purported effects of TRT on cortisol? It suppresses or stimulates the adrenals? As far as I know, the ACTH Stimulation test done at 8 am is the only valid way to assess adrenal function. Randomly checking blood cortisol at any time of the day outside of 8 in the morning or saliva...

Does taking melatonin multiple times during the day cause you insomnia or any sleep issues during the night?

Did they check your calcium level? Under Metabolic Profile