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    TRT in men in their Nineties

    Keep on keeping on! You're a role model. As to your question, I remember seeing that the body actually conserves T as we get older, however there are some people who just do better at higher levels so maybe you're one of them regardless of age. It may also be that if something else is in...
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    Left Ventricle Hypertrophy and Nandrolone ( Decadurabolin )

    I'm not opposed to nandrolone, however you generally can't optimize across all variables at once. If you want muscle gains, adding carbs and protein is likely necessary and that is what I would try first. What you don't want is visceral fat gain, but adipose tissue is likely no issue at all in...
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    WAS: 5 months post stopping TRT cold turkey bloodwork , NOW: Wife No Longer Wants Sex

    I am saddened by your situation and I hope that you find a resolution. Note that by restricting yourself to vows that your (former) "wife" has partially renounced, you may also be denying a potential romantic partner the same experience you are missing in your life. There is almost certainly a...
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    PT-141- New to peptides

    I am a big fan of PT-141 however i have not heard of it for this purpose, and if stimulating the melanocortin system does in fact help with visceral fat loss, I would suspect that it's Melanotan 2 you would want to try. Have you implemented Sean O'Meara's visceral fat loss protocol? Now that you...
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    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    Not that it matters for the purposes of this thread, but non-endogenous testosterone can be detected (using Isotopes IIRC) and WADA athletes are tested for it AFAIK. There was a Tour de France winner (before he was disqualified) whose name I am forgetting who tested positive for exogenous T.
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    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    Even things that are "bioidentical" can be detected as being from an external (likely lab-generated) source (e.g. testosterone and HGH). I'm not familiar with stanolone but the tests are very sophisticated so that is not a valid reason to consider stanolone to be a meaningfully different...
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    Sirolimus / Dialing in the Right Dosage and Protocol

    I think part of the reason metformin has fallen out of favor is chronic use at too high of a dosage. I take it on the occasions where I have a higher-carb meal and won't be active immediately after. That is usually no more than once per week and often less than that. I use either 250 or 500mg...
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    Sirolimus / Dialing in the Right Dosage and Protocol

    I would argue that this demographic is more likely to have chronically elevated mTOR for various reasons and, for anti-aging purposes, is more likely to benefit from reduced mTOR. IMO, the optimal dosage is likely unknowable given the hundreds of other variables involved, so for me, it's a...
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    PT-141 Appears to work great only when sleeping?!

    Nor-epinephrine decreases during sleep which IIRC has a pro-erectile affect. I and many others have found that PT-141 seems to require sleep to fully "activate" it. Away from sleep, I have found PT-141 to enhance the affect of the viagra-like compounds, but not to be miraculous on on its own...
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    Sirolimus / Dialing in the Right Dosage and Protocol

    I have been taking 4mg every two weeks for the last several years. I haven't noticed any strength decrease that would indicate a problem with MPS, and I am stronger overall. Blagosklonny, the last time I heard him interviewed, said that he thought part of the mechanism of action was reduction in...
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    22YO Natural Bodybuilder -- Seeking advice on Peptide Use

    I would start with DMSO. If that doesn't fix the issue (and not re-injuring the problem is essential) then BPC and or some form of GH secretagouge would be a good next step, as described above. 1-3 mg of BPC at a time injected close to the injury. I've had very good results with BPC patches...
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    Tadalafil Use in Cardiovascular Disease

    It seems to me that the benefits of tadalafil are sufficient that pretty much everyone (men and women) should be on a low dose past a certain age, whether it is beneficial for HF or not. Trying to figure out everything it benefits seems like a waste of money and time, given that it is about as...
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    Daily Cialis Plus Trimix?

    In theory, the combo should be superior for overall health due to the systemic cardio vascular benefits of the Cialis class of drugs, even if the erection results are the same.
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    Effect of Supplements on Endurance Exercise in the Older Population: Systematic Review

    I use it (synthagen) but I suspect I use too low of a dose and with too many other variables to really give a good evaluation based on results, but the logic behind it looks reasonable. That said, I would not trust any other brand that I'm aware of. It is apparently faked and diluted quite commonly.
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    Primobolan/Tren HRT No Test

    It's also worth noting that Tren and Primo both apparently have a very pronounced anti-libido/EQ affect in some people. It's especially unfortunate as Tren is one of the very few compounds that help resolve PE for some people, although I think Nandrolone may as well.
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    Podcast about SLU-PP-332; GLP-1, GIP, and glucagon (single, double, triple) agonists; and SARMs

    I ordered it on 2/16, so not too long ago. Also, I also appreciated your comment that Nandrolone increases synovial fluid and I refferenced you in one of the threads on here about that. That is a possible mechanism for reductions in joint pain that I had not seen before, but I'm far from an...
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    Podcast about SLU-PP-332; GLP-1, GIP, and glucagon (single, double, triple) agonists; and SARMs

    Welcome!!! I'm eagerly awaiting your book and look forward to your contributions. I am not on the other sites you post on (I am a believer in micro-dosing which seems to generate drama on some forums), but I do read and respect your work. I especially appreciated your reality check on Boldenone.
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    Should I continue trt or not?

    Since what I referring to is purely speculative and I haven't heard anyone else taking about it, doses and timing have to be guesswork. I don't remember what Dr. Denmeade's intervals are but I seem to recall that his dose was 600mg, although I could be way off. Anyway, if I was going to try the...
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    My Melanotan 2 experience.

    In my experience, that is a crazy-high dose. I would start at around 100-300mcg (micrograms) and gradually adjust high, but only if needed. This assumes you are looking for a bump in performance, not a wholesale transformation, in which case other options would be needed.
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    Just had 1st CT Angiogram Scan done. Anyone experienced care to comment in simple layman terms?

    It sounds like you are on a good path. The issue that jumps out at me is that Vitamin C is really important on many levels and likely at higher doses that most people get. If you take it away from high iron meals I wouldn't expect it to increase iron absorption since it is (as long as it's not...
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    Just had 1st CT Angiogram Scan done. Anyone experienced care to comment in simple layman terms?

    I'm sorry if you've already mentioned any of the following, but K2, potassium, Vitamin C and low dose aspirin seem like good additions. Moderating stress is also key. Something to raise or prolong nitric oxide is likely a good idea. Sunshine when you can get it has many benefits. If y9our lp(a)...
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    Should I continue trt or not?

    The decision tree here leads to one thing under all outcomes and that is to get on an anti-cancer protocol. That means things like keeping insulin and blood sugar low, no seed oils, HIIT activity, eliminate visceral fat, periodic fasting, anti-cancer supplements like curcumin, etc. Dr. Nasha...
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    REALLY Struggling With Weight Loss: What Labs to Run?

    I agree with this, but with the caveat that you don't want to put yourself into a state of overtraining. I would slightly cut back on something else and, to start, add one BRIEF workout per week of either sled-pushing or sprints on a slightly uphill slope. Total workout time should be no more...
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    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    Note that some compounds that increase "muscle size" are basically adding a lot of water retention (e.g. dianabol). There is a mechanism involving calcium IIRC that increases muscle contractile force without increasing the size or number of muscle cells. This used to be the goal of many anabolic...
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    REALLY Struggling With Weight Loss: What Labs to Run?

    My first thought was cortisol, but it looks like you've tested that. You might want to check your insulin levels and make sure fasting insulin is under 6 or so. You might also want to work with a holistic doc and test for chronic infections like mold exposure. I know people who have had very...
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    Long Term Clomid use experience

    Also, you might check out the book Adrenal Dominance which talks a lot about anxiety IIRC. I believe the author recommends a low dose of progesterone. Progesterone can be problematic in its own right for some men, however it may be worth looking into to combat anxiety.
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    Long Term Clomid use experience

    Two things...you might try some Lithium and see if that helps with your anxiety. Dr. Sandra Kaufmann thinks IIRC that 20-30mg per day is a reasonable dose, but you would obviously want to start low and adjust up to that only if needed. Also, when I was on clomid only, I could only tolerate a...
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    Has Anyone Tried Rad-140?

    The problem with this and similar compounds is they tend to be very temporary. There are fairly few things with enough of an experience base to be run fairly long-term even at lowish doses. Nandrolone is one for those who tolerate it. For RAD, LGD etc. there is a temporary boost, but for what...
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    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    In addition, Oxandrolone is one of the few anabolics to be considered Female-friendly, so it is unlikely to have the effect you're looking for, although it seems like there are exceptions to everything so it is worth a try, but if it helps you, I would not think it is because it is related to DHT.
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    Nandrolone (Deca) Base TRT Trial

    It's not clear why you would change anything if you are in a good place overall. 400mg per week is a hefty dose already.
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