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I started mounjaro (tirzepatide) nine months ago, but at the same time significantly increased my resistance training (focused on hypertrophy), regular cardio, and very focused effort to consume 150+ grams of balance protein daily. I could write many paragraphs on the benefits and fully body...

Selegiline is the drug favored by the scum Sam Bankman-Fried. He used the transdermal patch (Emsam).

100% agreed on the terp profile being most important. The problem with weed, for me, is it absolutely destroys my ability to manage appetite. Even on my GLP1 med, which is awesome for clamping down on any urge to overeat, any/all weed I have tried leads me straight to mind numbing eating...

I believe your body produces antibodies to most peptides, initially, but then you adjust and then no longer produce them. I am using Tirzepatide and a few months into it began to get a rash around the injection site (an inch or two) that was easily treated with Cortizone. That lasted a month...

which brand (sublingual) are you taking?

Not much action in this thread for over a year! But it’s a good one as I dial in my protocol. I just got my ultra-sensitive E2 back and it’s sitting at 63. TT at 760 ng/dL and free at 169 at pg/mL, measured at trough. All other markers look great, including SHBG (20 with range of 10-50)...

I feel like I luckily stumbled upon the holy grail combo (for me). I started TRT three months ago and Tirzepatide two months ago. Test is 100mg 1 x week and I recently graduated to the 10mg Tirz dose. I don’t obsess with the scale (record once/week). I’ve lost around 25 ‘net’ pounds (I’ve...

interesting to see new ("novel") evidence that high protein intake (greater than 3g per kg of body weight per day) has positive effects on body composition in resistance-trained people, i.e., promotes loss of fat mass.

The 'vacuum erection device' sounds like a high-tech cock ring. Searching Amazon now! Stem cells sound... interesting? I wonder if it acts as a localized "growth" catalyst :)

Ehh... no one should be blindly supplementing high dose Vit D but in my case I do not reach my target serum D levels of mid-70s without 10,000 IU/daily supplementation. Without that dose I am in the low 20s. Caveat that K2 and A supplementation is important as well. Some of us have a gene...

Script was easy: quick telemed appt with Push Health (or something like that), had Rx within a few hours. I did, however, inform my PCP. He was on vacation otherwise I would have gone through him. I have not done bloods so i don’t yet know what glucose levels are. The trials data are very...

I’m on Tirzepatide (Mounjaro), six weeks in, and I love it. It’s completely different from met or berberine (I usually include a lipo version of berberine) as it targets multiple mechanisms including effectiveness of insulin, activation of leptin receptors, slowed gastric emptying, appetite...

Is your +/- 100 circulating glucose number tested in a fasted state (i.e., morning before eating)? If so, I'm not sure metformin supplementation would impact that reading since it (along with any diet-related glucose) would seem to be long gone from your system by the time you are pulling...

Any validity to the notion that joint/ligament/tendon health actually suffers MORE from higher reps (vs. lower reps/heavier weight)?

This is my experience and I am now experimenting with supplemental cream on days 5 and 7 (scrotum). Amount is cream is equivalent to apprx 8mg, so not very much. But it is working well for me so far (and I like the light "DHT" bump!)

Since you are continuing with the Atrevis base I assume no skin irritation for you? I developed some annoying bumps and itchiness and had to discontinue (scrotum itching was the worst!)

I am dialing in my sweet spot protocol using the "how I feel" method. I started with cream only (100mg/week equivalent), which I liked a lot (50% scrotal, 50% collarbone area) but my skin did not like it (itchy bumps and rashes). I then switched to once/week 100mg Test E injection (xyosted)...

I love this stuff, has really changed my relationship to food as an energy source. The first two days after this 5mg step-up has been pretty nausea-inducing, but I have a sense of humor about it because I know it is fading quickly. A few days of nausea is my only side. I also felt a bit like...

Nice, I am in week 5 (just now starting 5mg, up from the 2.5mg starter dose)

I am two weeks in to starting Tirzepatide, which is similar to Semaglutide but is also a GIP receptor agonist. I've discovered that I am leptin resistant from two decades of undiagnosed sleep apnea. The GLP-1/GIP receptor agonist helps to correct my leptin resistance. For years I've literally...

Argh, this is what I am going through with the hydrogel base. I end up scratching balls too much in my sleep which leads to irritated sackage, almost like an eczema breakout. I am "mostly" ok alternating shoulders/pecs (with one click every few days on the scrot for a DHT boost), but at least...

excellent description No Doc. For some people - hopefully myself included - I think the GLP-1 agonists (and +GIP agonists) see and understand these drivers (Ghrelin, Dopamine, fuel needs) clearly for the first time.