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My summary https://www.discountedlabs.com/blog/lower-high-hematocrit-strategies

https://www.excelmale.com/threads/hematocrit-drives-blood-viscosity-does-that-matter-in-men-on-trt-effect-of-altitude.18114/

This is a very detailed explanation of the mechanism of action involved in testosterone- induced high hematocrit: https://www.excelmale.com/threads/testosterone-therapy%E2%80%93induced-erythrocytosis-can-phlebotomy-be-justified.30994/

Debunking the Myth About High Hematocrit in Men on TRT I know many of you want to feel reassured that managing hematocrit isn’t necessary. However, misinformation is spreading, with some "bro science" videos and even a few so-called expert doctors claiming that men on TRT don’t need to worry...

@Systemlord I know all of you want to feel OK about not having to manage hematocrit. Ok, time for me to AGAIN repeat the same info I have repeated in the past to debunk this wrong information. The Internet "gurus" and even some "expert doctors" want to oversimplify things without any deep...

Therapeutic phlebotomy, which is also called bloodletting, is a medical procedure. It involves removing blood in a controlled way. The goal is to lower the levels of red blood cells in the body. Therapeutic phlebotomy is similar to blood donation. It can reduce hematocrit levels by about 3...

What is your blood pressure? High BP can cause headaches. In my opinion, the best indicator of the need for blood donation is high blood pressure+ hematocrit above 52. Having normal blood pressure is an indicator that your blood vessels are still handling higher hematocrit OK.

This is THE test to get: https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ms

From Perplexity: The Impact of Oxandrolone and Testosterone Injections on Immunoassay-Measured Testosterone Levels The concurrent use of oxandrolone (20 mg/day) and testosterone injections (160 mg/week) can significantly alter immunoassay-measured testosterone levels through both...

taking it with TRT?

https://www.excelmale.com/threads/tirzepatide-vs-semaglutide-pros-and-cons.30741/

Tirzepatide Dosing for Weight Loss: A Guide Tirzepatide is a big deal in weight management pharmacology. As a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, tirzepatide has worked amazingly well in clinical trials for weight loss...

Re-evaluating testosterone therapy: new insights for men with familial prostate cancer risk https://bmjoncology.bmj.com/content/4/1/e000635

https://bmjoncology.bmj.com/content/4/1/e000520 The main findings of the study on prostate cancer risk in men with testosterone deficiency (TD) and a family history of prostate cancer (PCa) receiving testosterone therapy (TTh) are: - **Prostate Cancer Risk:** There was no significant...

https://www.theatlantic.com/health/archive/2025/03/ketamine-effects-elon-musk/681911/

Quote from the article above: Alarming Mistrust of MDs O'Connor's study shed some light on why AAS users might resort to surfing the internet looking for a way to diagnose their own complications from steroid use. The web-based survey of nearly 2400 men who said they took the drugs found that...

I would say YES, as long as you educate yourself with the info we provide here.

This Medscape article mentions Dr O'Connor, me and others. Before he attended medical school, Thomas O'Connor, MD, had a not-very-well-kept secret: As a competitive powerlifter, he had used steroids to build strength. Dr Thomas O'Connor Now an internist and clinical instructor of medicine at...

"I would love to see clinical trials with nandrolone where BP is maintained in a healthy range the entire trial, and see if it still increases the chances of getting LVH. And have another group on the same dose, but of testosterone" This would be great, but I doubt it will ever happen with a...

https://www.excelmale.com/threads/effects-of-testosterone-and-nandrolone-on-cardiac-function.21874/

Great. Just be aware of these changes but make BP management the main goal (some guys do not experience increased blood pressure at all). When used with TRT, nandrolone (like all anabolics) has the following effects on blood work and quality of life: Free T goes up HDL goes down SHBG goes...

Hey guys Very good and interesting conversation about partners not responding anymore to intimacy and sexual advances, making it difficult to satisfy your improved sex drive with TRT. I would like to move all posts related to the new topic to a separate thread with a proper title, "How to...

The best way to prevent the hypertrophy of the left ventricle is to make sure you manage your blood pressure on TRT and or nandrolone. Losartan (or other similar ARBs) is a good choice when your BP starts going up. From Perplexity. # Protective Properties of Angiotensin Receptor Blockers...

There are several direct-to-consumer blood testing companies operating in the UK. Some notable examples include: Medichecks: Established over 20 years ago, Medichecks was the UK's first direct-to-consumer blood testing service78. They offer private blood tests and at-home health checks with...

It seems to me that some people are getting it somehow. https://www.excelmale.com/threads/dht-cream-plus-testosterone-propionate-major-libido-boost.30965/

Interesting article to say the least ! https://www.ft.com/content/350c3ebe-5afe-41c0-a90a-adc70e3ab771

I am sure they are stacking it not only with TRT but also with other products. 5-10 mg per day is the female dose.

I wonder what the effect on VO2 max and muscle is with the use of Rapamycin . Metformin, another mTOR reducer, decreases both.

Interesting! This is what I found through a Perplexity search: Yes, Cardarine has been shown to raise HDL (good cholesterol) levels in several studies. For example, a 12-week study demonstrated that doses of 10 mg per day increased HDL cholesterol by up to 16.9%, along with improvements in...

Drug compounders sue over weight loss drugs’ removal from FDA shortage list https://thehill.com/policy/healthcare/5163570-weight-loss-drugs-fda-shortage-list-ozempic-wegovy/

https://www.excelmale.com/threads/higher-heavy-metal-blood-levels-in-men-with-idiopathic-hypogonadotropic-hypogonadism-ihh.29806/