Sermorelin and acne

Dasein88 · Jan 4, 2026

I started sermorelin a month ago. After a couple of weeks, I started noticing my acne getting really bad. Has anyone else experienced this?

I contacted my provider and he said I should talk to a dermatologist. He was unhelpful.

I’m not going to keep using it if it gives not acne. I stopped taking it a few days ago and I’m still dealing with bad acne.

Any thoughts?

Nelson Vergel · Jan 4, 2026

Sermorelin increases IGF-1, which may worsen acne:

Thread 'Influence of IGF-1, DHEA and DHT on acne'

Jun 23, 2017

Arch Dermatol. 2005 Mar;141(3):333-8.

Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women.

Abstract

OBJECTIVES:
To determine if insulin-like growth factor 1 (IGF-1) and androgen levels (1) correlate with the presence and severity of acne in adult men and women, and (2) correlate directly with each other and interact in affecting acne.

DESIGN:

Case-control study and single-center examination of hormone levels in a cohort of volunteers.

SETTING:

Academic referral...

Dasein88 · Jan 4, 2026

Nelson Vergel said:
Sermorelin increases IGF-1, which may worsen acne:

Thread 'Influence of IGF-1, DHEA and DHT on acne'

Jun 23, 2017

Arch Dermatol. 2005 Mar;141(3):333-8.

Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women.

Abstract

OBJECTIVES:
To determine if insulin-like growth factor 1 (IGF-1) and androgen levels (1) correlate with the presence and severity of acne in adult men and women, and (2) correlate directly with each other and interact in affecting acne.

DESIGN:

Case-control study and single-center examination of hormone levels in a cohort of volunteers.

SETTING:

Academic referral...

Nelson Vergel

Replies: 0

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