Cannabis and DHT

Seagal · Sep 12, 2024

Regulatory Effect of Cannabidiol (CBD) on Decreased β-Catenin Expression in Alopecia Models by Testosterone and PMA Treatment in Dermal Papilla Cells

The hair follicle is composed of more than 20 kinds of cells, and mesoderm derived dermal papilla cells and keratinocytes cooperatively contribute hair growth via Wnt/β-catenin signaling pathway. We are to investigate β-catenin expression ...

www.ncbi.nlm.nih.gov

Marihuana inhibits dihydrotestosterone binding to the androgen receptor - PubMed

Marihuana and its constitutents delta 9-tetrahydrocannabinol (delta 9-THC) and cannabinol (CBN) were tested for their ability to interact with the androgen receptor in rat prostate cytosol. Smoked marihuana condensate, delta 9-THC, and CBN inhibit specific binding of dihydrotestosterone (DHT) to...

pubmed.ncbi.nlm.nih.gov

Flexityme · May 28, 2025

I see it's been a while since you've posted, but I just want to ask if anyone here has done recent bloodwork while actively using cannabis? I'm curious if you noticed any shifts in DHT or testosterone levels, especially with consistent use. Also wondering if anyone tried switching strains—like high *** vs. high THC—to see if that made a difference. Would be great to hear some updated personal experiences.

Vince · May 28, 2025

Interesting, I wonder if it's true?

Harmnapt · Jun 3, 2025

I’ve ended up trying cbn water soluble as an easier way to manage my sleep without smoking or vaping. I didn’t notice any big changes in DHT levels from it, and my bloodwork stayed stable. Everyone reacts a bit differently, but switching to water soluble options like that helped me control the dosage better and avoid some of the stronger effects from THC.

Vince · Jun 3, 2025

Harmnapt said:
I’ve noticed that when I use cannabis regularly, my DHT drops a bit and I feel it in terms of libido and energy. Cutting back brings things back to normal.

Does cannabis increase your libido and orgasms?