Recent content by Rand McClain DO

Can't say for sure if the culprit is estrogen or prolactin, but, again, by blocking conversion from T to DHT, there is more T available for conversion to E, and you note that this is indeed what you saw with your assays. Yes, low DHT, in and of itself, does not drive gynecomastia. A T cycle, if...

Hi eudes, you are very welcome. I can Skype with you if you like. Regarding your concern for your lipids, as long as you are not OVERsuppressing your estrogen, you should have no negative effect on your HDL. You can avoid gynecomastia (estrogen related) by keeping your E within normal limits...

Hi Fernando, Thank you and thank Nelson for this! And, for the videos, the credit goes to Dave "Mad Max" Bourlet (btw, we are now on Jay Cutler's channel/website) For my part, I am more than happy to help if I can. I do not see how an AI would lead to osteoporosis in a typical male. If one were...

Hi Galaxy, one of the main reasons for not "endorsing" sub Q injections of T was because it was relatively new (at least in terms of being main stream). I (arguably, we) just didn't have enough data/feedback, and, I had seen some pretty bad case of sub Q injections gone bad - mainly large blebs...

Hi eudes, There is no contraindication taking dutasteride with anastrozole (Arimidex). You may indeed get better results with dutasteride than finasteride. Gynecomastia is not driven by DHT but rather estrogen. If you take a 5-alpha reductase inhibitor such as finasteride or dutasteride and you...

That's a loaded question for many more reasons than legalities. There are so many, not just androgens, but steroids that have therapeutic value. To which therapeutic purpose(s) are you referring? For simple anabolic purposes, two anabolic steroids that are legal in the US are nandrolone and...

Hi lexer, Not sure if I answered your question, but it appears that at some point I hadn't. Sorry to you and others whose questions I haven't answered. I screwed up initially answering questions without tying them to each other (question with answer) so I frankly got lost in what had and hadn't...

Hi Blackhawk, I am still not convinced that PSA is a valuable screening tool. Even the supposed inventor of the PSA test believes it should not be used as such (https://www.nytimes.com/2010/03/10/opinion/10Ablin.html). The only group the adheres to its use still is the AUA. There are too many...

Hi Mike (Sully09), First, you are in good hands with Defy Medical. I actually founded Defy along with one of the current owners and Dr. Saya is very knowledgeable and competent. There is more than one way to skin a cat, so we may vary in our preferences for different Rx's and protocols, but...

Hi HanginOn, I use E2 (estradiol), sensitive for just that reason. Once I received a report with both and the E2 was 64 pg/mL while the E2, sensitive was 16 pg/mL on the same draw. This is typical because the simple E2 is not precise enough in the low range likely because the test was originally...

Hi Amacher, Of course, everyone is different, but the pituitary usually picks up where it left off pretty quickly. I refer to it as similar to a gas powered engine as opposed to a diesel. The length of time using HGH and one's age plays a very large role in the speed at which you regain your...

Hi blackebob, The bloat you experienced is most likely caused by excess estrogen generated using HCG. Did you take anything along with the HCG to block testosterone's conversion to estrogen or estrogen receptors? If not, try adding anastrozole (my preference because an aromatase inhibitor will...

No, dutasteride is "stronger" in that it works on all three receptors (rather than two as does finasteride) and has a much longer half-life (5 weeks!). So, if you have any unwanted SE's with finasteride, I would not use dutasteride. However, if you have know SE's with finasteride, but not enough...

Typically, your T levels will spike about 2.5 days after your injection of T Cyp, BUT, this average is wide, in my experience, meaning for some it is earlier and some later by a day or more. So, your DHT levels will spike in accordance with your T spikes because DHT is made from T and is fairly...

My first question is why did you switch from a daily topical to daily injectable? One of main ideas behind use of an esterified form of T is to avoid daily dosing, so I am always suspicious when I hear of daily injections. As for the HCG and bloating, it is most likely secondary to excess...