Recent content by eyeheartny

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    Water Retention While on TRT May Only Occur to Certain Men

    Which electrolytes can help shift the balance toward holding less water? Potassium, right? Any others?
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    Switch to IM from SQ? Lower E2? Sleep, digestion, maybe lower Free T...

    Appreciate this very much. I don't think it's worth the trouble at this point to try dailies or multiple esters. Interestingly, I tried a few things last night/today that seem to have helped with both sleep and constipation. I applied a little bit of progesterone cream to my scrotum before bed...
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    Switch to IM from SQ? Lower E2? Sleep, digestion, maybe lower Free T...

    Yes, test was at trough. Would there be any merit to trying IM to see if it changes the metabolism? Are there any concerns with the fact that I appear to metabolize testosterone fast? Would this point toward doing daily shots as a better option? I inject at night before bed but could also switch...
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    Switch to IM from SQ? Lower E2? Sleep, digestion, maybe lower Free T...

    in the past I’ve lowered my estradiol and my constipation has improved. My sleep has also been better when my E2 was lower. This was of course when my SHBG was lower as well, so my free T was comparatively higher. So that makes me wonder about raising my dose as you suggested to try and boost...
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    Switch to IM from SQ? Lower E2? Sleep, digestion, maybe lower Free T...

    Long-term TRT patient, current protocol is 154mg/week in EOD SubQ shots (into thigh, belly, hip, etc). I've struggled on and off with digestion issues (constipation) and lack of deep sleep. A few months ago I started intermittent fasting and it's been good for dropping some weight. That combined...
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    Anyone combine injections and cream? How do you feel?

    It took a fair bit of research to determine this, but there's a strong correlation between testosterone and inhibition of ACTH, which is what causes your body to release cortisol. It's very very possible that your body is especially sensitive to testosterone's effects on the HPA axis and that...
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    Anyone combine injections and cream? How do you feel?

    Once again, it's great that HC works for you. That said, no one can provide an explanation as to your stuff without more information. I'd suggest starting a new thread of your own with bloodwork, relevant medical history, what interventions you've described, etc. I am still not sure what you're...
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    Anyone combine injections and cream? How do you feel?

    It sounds like you need some expert help on that, and I am not that expert. If you're having trouble waking up that late I'd seek medical attention and help-- that sounds really difficult and could be related to serious endocrine issues. Also, dosing of HC and those protocols is way outside of...
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    Anyone combine injections and cream? How do you feel?

    Yep. That's why I'm thinking of going to a protocol that allows for more variation. I started off my TRT 9 years ago on EOD so I have literally been running at a steady level that entire time. I suspect there's a lot of processes that have been slowed/inhibited by this, so it's why I'm looking...
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    Anyone combine injections and cream? How do you feel?

    Cypionate. The short-acting leg would be either prop or cream.
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    Anyone combine injections and cream? How do you feel?

    SHBG is low 20s consistently. Thyroid function was fine as of last March (haven't done labs since COVID), Free T3 top of range, free T4 low normal, TSH low end of normal, rT3 low end of range. I tried adding T4 and felt like I was going to die so that wasn't the right solution. Cortisol is low...
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    Anyone combine injections and cream? How do you feel?

    What is your SHBG? And what does that dose get your levels to? I'm only in the 700s at my current dose of 154mg/week.
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    Dissolving testosterone for sublingual or intranasal

    I wonder if the testosterone used in this preparation has an ester attached or is ester-free. If esterified testosterone can be absorbed intranasally that would be really interesting. Also curious if esterified testosterone can be dissolved in alcohol. @Cataceous do you happen to know or have...
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    Anyone combine injections and cream? How do you feel?

    I’m a long term TRT patient, 39 years old. I’ve been on cypionate and inject a total of 154mg weekly in EOD subQ shots of 44mg each. I have been doing some thinking about the potential benefit of keeping dosing the same but experimenting with using a low cypionate base around 80-100mg weekly...
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    Water Retention While on TRT May Only Occur to Certain Men

    But isn't that inaccurate? I thought we know now that E2 is not the enemy and not the proximate cause of water retention.
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