Recent content by engineer

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    Is there hope for degenerative disk disease?

    Although I had already 2 prior surgeries including a 3-level fusion (L4-L5-S1) performed in 2017 due to emergency Cauda Equina Compression in my record, I needed to have a 3rd one done due to some new neurological symptoms, including pain (lumbar, sciatica et.al.). With that, I did some...
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    Anyone combine injections and cream? How do you feel?

    wow, thanks a lot for your response. You went above and beyond what I was expecting.... Just to clarify a few things and confirm what you found in previous posts: 1) I am used to use a low dose of AI from the get go from Defy: - 70mg Test - twice per week - Some HCG which I stopped due to...
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    Anyone combine injections and cream? How do you feel?

    You are right, I will gather my previous protocols with lab work and start my own thread. I only asked you here because it was the first time that I read about a relationship between Testosterone levels with Cortisol levels. Until now, I was taking my medications but always thinking "what's...
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    Anyone combine injections and cream? How do you feel?

    Thanks for your reply! My thyroid numbers are great, my Test levels are high, but I am still sleepy.... I have been asking for help to the medical community for 4 years with no one listening to me other than prescribing stimulants/antidepressants. And they didn't help unfortunately...
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    Anyone combine injections and cream? How do you feel?

    Could you please elaborate on this?? My cortisol is low... ultra low to the point that I only wake up after 2PM. Hydrocortisone helps a lot but at what dose does it become “dangerous”?
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    Issues with Testosterone Cream -- anyone else?

    I take 25mg to try to maintain the muscle mass on one of my legs. Honestly I would need a higher dose but at 25mg/day, it only tanks my HDL cholesterol. My liver enzymes are not affected much if at all so at the doses you mentioned, I would think that the side-effects would be very mild ...
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    Issues with Testosterone Cream -- anyone else?

    No problem! My oxandrolone dose is 25mg/day and it is part of my HRT protocol ... I mean, Dr. Saya prescribes it but like I said, it is due to a wasting problem on my leg (it wouldn’t be necessary for my TRT)
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    Issues with Testosterone Cream -- anyone else?

    That’s a clever solution. I will discuss that with Dr. Saya... or maybe, since I barely aromatize on the cream, use the cream as a base and titrate Tcyp and HCG. Or even use Oxandrolone as a base (which I am prescribed for a wasting problem on my leg due to a spinal chord injury) instead of...
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    Issues with Testosterone Cream -- anyone else?

    You may be onto something about the DHT vs E2 on the cream. I am still struggling with low E2 unless I use HCG which is almost impossible to dial in. I have a consult with Defy in about 2 weeks... hopefully they can figure something out like adding Tcyp for example. Let’s see... Thanks for...
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    Issues with Testosterone Cream -- anyone else?

    Could you please elaborate more on this? I have been on several protocols using injections and my E2 have always had to be controlled by AIs to manage symptoms. Upon changing my protocol to T cream on my shoulders, E2 was undetected (TT=400s). Then started to apply 150mg to my belly, my E2...
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    Antidepressants

    Hi L2S, Hope you are doing better by now! In case you didn't start the medication yet, I would definitely talk to the doctor to add Bupropion XL (300mg once a day) like others suggested to the SSRI. SSRI's are great for anxiety and panic attacks but not that great for depression which involves...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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